Research News and Research

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Hormone-like inner ear signaling system protects against noise-induced hearing loss

An in vivo study shows for the first time that there is a stress-response system within the cochlea that mirrors the signaling pathways of the body's fight or flight response. Researchers have identified a hormone-like signaling system of the inner ear that sets baseline hearing sensitivity and helps protect against noise-induced hearing loss.

4 May 2010

Study indicates a strong link between socio-economic status and asthma

New research shows Inuit populations in the Canadian Arctic have asthma rates far below Aboriginal people in other parts of Canada, especially those in urban centres.

4 May 2010

JGH researchers identify 13 new genes associated with osteoporosis, bone weakness

A team of international researchers has identified 20 genes associated with osteoporosis and bone weakness, including 13 genes never previously associated with the disease. Osteoporosis is a highly heritable trait, but this marks the largest international effort to conclusively identify genes linked to the often-devastating bone disorder.

4 May 2010

Informative session on TP-drug interactions

AAPS is pleased to present the workshop on Strategies to Address Therapeutic Protein Drug Interactions during Clinical Development. This event will feature a review of pre-clinical tools, test systems, and relevant documented Therapeutic Protein-drug interactions.

4 May 2010

Study shows association between sleep duration and weight in adolescents

Adolescents who don't get enough sleep may gain more than some extra time to play video games or text their friends. They also may gain weight, according to research being presented Tuesday, May 4 at the Pediatric Academic Societies annual meeting in Vancouver, British Columbia, Canada.

4 May 2010

New breakthrough in nutritional plant breeding may save children’s eyesight

Two Agricultural Research Service (ARS) scientists are part of an international team that has found a way to boost the nutritional value of corn. This has the potential to reduce the number of children in developing countries who lose their eyesight, become ill or die each year because of vitamin A deficiencies.

4 May 2010

Despite FDA black box warning, prescription of Reglan for premature infants continue

Recently, researchers have observed a disturbing trend in neonatal units across the country: doctors prescribing Reglan -- also known by its generic name, metoclopramide -- to treat premature infants. This alarming development has raised serious concerns from many consumer safety advocates, particularly because the drug was never approved for use in infants.

4 May 2010

Prenatal tobacco smoke exposure can increase risk of developmental problems in African American children

Low levels of prenatal tobacco smoke exposure are associated with a higher risk of developmental problems for African American children than white children, according to new research from Cincinnati Children's Hospital Medical Center.

4 May 2010

Skin cancer rates going down in Alberta: Research group

It appears that people are listening to doctors' orders to protect their skin from the sun. In the largest Canadian study of non-melanoma skin cancer, Andrei Metelitsa, Gordon Jung and their research group have found skin cancer rates in Alberta are going down in men and have levelled off for women. This comes at a time when American scientists say that skin cancer rates are on the rise.

4 May 2010

Scientists introduce a new way of identifying key cancer genes

A new study shows that a family of molecules called microRNA work together in single, well-connected networks to control many important functions in healthy cells, but that in cancer cells the networks are rewired and fragmented.

4 May 2010

Rush Center for Urban Health Equity to focus on disparities in heart and lung disease

Rush University Medical Center has been awarded a $10 million grant from the National Institutes of Health to establish the Rush Center for Urban Health Equity. The aim of the Center is to find ways to promote changes to eliminate the disparities in heart and lung disease affecting inner city residents, in particular those who are low-income persons of color.

4 May 2010

New diagnostic tool could help detect heart attacks

A diagnostic tool developed by Rice University scientists to detect heart attacks using a person's saliva is being tested at the Michael E. DeBakey VA Medical Center in collaboration with Baylor College of Medicine in Houston.

4 May 2010

Opinions: Malaria bed net concerns; Catholic Church's humanitarian work; Abortion, global health; Foreign aid reform; Canada's G8 initiative

"To date, millions of dollars from international agencies, NGOs and USAID have been spent to get treated nets into the hands of impoverished, sub-Saharan Africans [to prevent malaria]. ... But, as even the staunchest advocate will admit, the treated nets were not designed with the cultural preferences of the rural African villager in mind," Sonia Shah, author of upcoming book about malaria, writes in a Los Angeles Times opinion piece.

4 May 2010

Researchers present positive results of Phase II clinical trial of eliglustat tartrate

Gaucher disease, a rare enzyme deficiency disorder, is one of many conditions with few approved treatment options for patients. In a study published online today in Blood, the journal of the American Society of Hematology, researchers present positive results of a Phase II clinical trial of eliglustat tartrate, an oral therapy in development to treat Gaucher disease.

4 May 2010

Broccoli component sulforaphane targets and kills breast cancer stem cells

A compound derived from broccoli could help prevent or treat breast cancer by targeting cancer stem cells -- the small number of cells that fuel a tumor's growth -- according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.

4 May 2010

Statins may improve longevity of hip replacement surgery

The use of statins - drugs commonly prescribed to help lower cholesterol levels - may play an important role in decreasing complications among patients undergoing total hip replacement (THR), according to a study published in the May 2010 issue of the Journal of Bone and Joint Surgery (JBJS).

4 May 2010

Researchers convert established human iPS cells, ES cells to base state of greater pluripotency

Whitehead Institute researchers have converted established human induced pluripotent stem cells and human embryonic stem cells to a base state of greater pluripotency.

4 May 2010

One-half of physicians do not recommend bariatric surgery for adolescents

Severely obese adolescents may desire or potentially benefit from bariatric surgery. However, half of primary care physicians say they would not recommend the procedure to a patient under the age of 18, according to research published in Obesity Surgery

4 May 2010

NIH awards Hutchinson Center $10.24M for research of breast cancer disparities in Hispanic women

The National Institutes of Health has awarded $10.24 million to Fred Hutchinson Cancer Research Center to lead a five-year study that aims to understand and prevent breast cancer disparities in Hispanic women.

4 May 2010

TB Alliance, AstraZeneca sign research collaboration agreement to develop drugs against tuberculosis

The Global Alliance for TB Drug Development and AstraZeneca announced today at the 2010 BIO International Convention that they have entered into a research collaboration agreement to accelerate the discovery, development and clinical use of drugs against tuberculosis, including drug resistant strains of the disease.

4 May 2010

Research News and Research

Hormone-like inner ear signaling system protects against noise-induced hearing loss

Study indicates a strong link between socio-economic status and asthma

JGH researchers identify 13 new genes associated with osteoporosis, bone weakness

Informative session on TP-drug interactions

Study shows association between sleep duration and weight in adolescents

New breakthrough in nutritional plant breeding may save children’s eyesight

Despite FDA black box warning, prescription of Reglan for premature infants continue

Prenatal tobacco smoke exposure can increase risk of developmental problems in African American children

Skin cancer rates going down in Alberta: Research group

Scientists introduce a new way of identifying key cancer genes

Rush Center for Urban Health Equity to focus on disparities in heart and lung disease

New diagnostic tool could help detect heart attacks

Opinions: Malaria bed net concerns; Catholic Church's humanitarian work; Abortion, global health; Foreign aid reform; Canada's G8 initiative

Researchers present positive results of Phase II clinical trial of eliglustat tartrate

Broccoli component sulforaphane targets and kills breast cancer stem cells

Statins may improve longevity of hip replacement surgery

Researchers convert established human iPS cells, ES cells to base state of greater pluripotency

One-half of physicians do not recommend bariatric surgery for adolescents

NIH awards Hutchinson Center $10.24M for research of breast cancer disparities in Hispanic women

TB Alliance, AstraZeneca sign research collaboration agreement to develop drugs against tuberculosis

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

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