Genes News and Research

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Largest data set of cancer-specific genetic variations generated by NCI scientists

Scientists at the National Cancer Institute have generated a data set of cancer-specific genetic variations and are making these data available to the research community, according to a study published in Cancer Research, a journal of the American Association for Cancer Research.

16 Jul 2013

Researchers develop new test to detect E. coli at food processing facilities

Medical, agriculture and computer science researchers from the University of Alberta have teamed up to develop a test that will make Canadians feel safer about the meat they put on their tables.

16 Jul 2013

Pair of studies sheds light on cancer cell signaling

A pair of studies by a team of University of Notre Dame researchers led by Crislyn D'Souza-Schorey, professor of biological sciences, sheds light on a biological process which is activated across a vast range of malignancies.

16 Jul 2013

White blood cells and the spread of cancer: an interview with Drs. Lorenzo Ferri and Jonathan Cools-Lartigue, McGill University

As surgeons who take care of cancer patients, we have observed a troubling association between patients who suffer from infections after surgery and the rapid spread of their cancer. We have reported this in lung cancer patients, and others have made these observations in a variety of different cancers. However, the mechanisms responsible for this association are still poorly understood.

16 Jul 2013

Researchers identify genes that allow animal hepatitis E virus strains to infect humans

X.J. Meng, a University Distinguished Professor at Virginia Tech and a virologist at the Virginia-Maryland Regional College of Veterinary Medicine, has received a four-year, nearly $1.6 million grant from the National Institutes of Health to better understand the genetic elements that allow hepatitis E virus to transfer from animals to people.

16 Jul 2013

CUMC researchers develop new approach to tailor cancer therapy for individual patient

Columbia University Medical Center (CUMC) researchers are developing a new approach to cancer clinical trials, in which therapies are designed and tested one patient at a time.

16 Jul 2013

Researchers discover that JNK3 expression is downregulated at early stages of traumatic brain injury

Increasing evidence has revealed that the activation of the JNK pathway participates in apoptosis of nerve cells and neurological function recovery after traumatic brain injury.

16 Jul 2013

Researchers distinguish viral and bacterial infections in children with fever

In children with fever but no other symptoms of illness, it is difficult to know whether a child has a viral infection that will resolve on its own or a potentially serious bacterial infection that requires antibiotics.

16 Jul 2013

Scientists discover how BRCA1 gene mutations predispose women to breast and ovarian cancers

Scientists led by Drs. Mona Gauthier and Tak Mak at The Campbell Family Institute for Breast Cancer Research at the Princess Margaret Cancer Centre have solved a key piece in the puzzle of how BRCA1 gene mutations specifically predispose women to breast and ovarian cancers.

16 Jul 2013

Proteins involved in immunity produce cancer-causing DNA mutations, study finds

A set of proteins involved in the body's natural defenses produces a large number of mutations in human DNA, according to a study led by researchers at the National Institutes of Health. The findings suggest that these naturally produced mutations are just as powerful as known cancer-causing agents in producing tumors.

15 Jul 2013

High folate intake during pregnancy may have undiscovered later-life effect in progeny

During pregnancy, women are normally advised to take high amounts of multivitamin supplements. In particular, folate is recommended to reduce the risk of neural tube defects in newborns. The problem is that, although vitamins are critical in fetal development, high vitamin doses during pregnancy may cause undesired effects on the offspring later in life.

15 Jul 2013

New discovery reveals how RNA moves genetic information from DNA to create proteins

The discovery cracks the "RNA control code," which dictates how RNA - a family of molecules that mediates DNA expression - moves genetic information from DNA to create proteins.

15 Jul 2013

New theory challenges orthodox view that cancer develops in each host by mutational accidents

A new way to look at cancer -- by tracing its deep evolutionary roots to the dawn of multicellularity more than a billion years ago -- has been proposed by Paul Davies of Arizona State University's Beyond Center for Fundamental Concepts in Science in collaboration with Charles Lineweaver of the Australian National University.

15 Jul 2013

'Defanged' HIV used to deliver gene therapy

Researchers are having success using a "defanged" version of HIV to deliver gene therapy to children suffering from genetic diseases, a development that could improve other such care.

15 Jul 2013

First Edition: July 12, 2013

Today's early morning highlights from the major news organizations, including articles on data tracking of doctors and comparing the rollout of the Medicare Part D drug plans to implementation of the federal health law.

12 Jul 2013

International team explores genetic diversity of Plasmodium vivax in the Americas

Human migrations - from the prehistoric epoch to the present day - have extended cultures across the globe. With these travelers have come unwanted stowaways: mosquito-borne parasites belonging to the Plasmodium species - a group responsible for malaria, worldwide.

12 Jul 2013

Genome sequencing promises to identify rare mutations that give rise to autism

An international consortium, consisting of Autism Speaks, Duke University School of Medicine, The Hospital for Sick Children of Toronto, BGI and other institutes, has investigated the genetic variants in 32 families with Autism Spectrum Disorder (ASD).

12 Jul 2013

Risk-factor screening of high-risk children may delay or prevent chronic health conditions later in life

Mexican American children are experiencing substantial burdens of obesity, pre-diabetes, and other health problems which historically would have been expected to develop much later in life. The findings of a new study by Texas Biomed scientists in San Antonio argue for early screening and intervention to delay or avoid chronic health problems as these children age.

12 Jul 2013

Patients suffering from severe Charcot-Marie-Tooth disease can benefit from reconstructive surgery

For patients suffering from Charcot-Marie-Tooth disease - a surprisingly common neurological disorder that can cause the feet to become weak and contorted - surgery is considered a last resort. But for patients like Elissa Williams and her brother Kyle, surgery can bring an end to crippling pain and lead to active lives with feet facing forward and balanced on the ground.

12 Jul 2013

Scientists evaluate past outbreaks and pandemic potential of H7 subtype influenza viruses

The emergence of a novel H7N9 avian influenza virus in humans in China has raised questions about its pandemic potential as well as that of related influenza viruses.

12 Jul 2013

Genes News and Research

Largest data set of cancer-specific genetic variations generated by NCI scientists

Researchers develop new test to detect E. coli at food processing facilities

Pair of studies sheds light on cancer cell signaling

White blood cells and the spread of cancer: an interview with Drs. Lorenzo Ferri and Jonathan Cools-Lartigue, McGill University

Researchers identify genes that allow animal hepatitis E virus strains to infect humans

CUMC researchers develop new approach to tailor cancer therapy for individual patient

Researchers discover that JNK3 expression is downregulated at early stages of traumatic brain injury

Researchers distinguish viral and bacterial infections in children with fever

Scientists discover how BRCA1 gene mutations predispose women to breast and ovarian cancers

Proteins involved in immunity produce cancer-causing DNA mutations, study finds

High folate intake during pregnancy may have undiscovered later-life effect in progeny

New discovery reveals how RNA moves genetic information from DNA to create proteins

New theory challenges orthodox view that cancer develops in each host by mutational accidents

'Defanged' HIV used to deliver gene therapy

First Edition: July 12, 2013

International team explores genetic diversity of Plasmodium vivax in the Americas

Genome sequencing promises to identify rare mutations that give rise to autism

Risk-factor screening of high-risk children may delay or prevent chronic health conditions later in life

Patients suffering from severe Charcot-Marie-Tooth disease can benefit from reconstructive surgery

Scientists evaluate past outbreaks and pandemic potential of H7 subtype influenza viruses

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