Mortality News and Research

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Restoration of natural water flows can cause ecological harm

Conservation projects often attempt to enhance the water-based transport of material, energy, and organisms in natural ecosystems. River restoration, for example, commonly includes boosting maximum flow rates.

5 Jan 2010

January issue of Chest presents new studies on COPD

A new study shows that poor lung function during adolescence and through midlife may be influenced by several factors, including birth weight, height, and gender.

5 Jan 2010

SBI and ACR publish new recommendations on breast cancer screening

The new recommendations from the Society of Breast Imaging (SBI) and the American College of Radiology (ACR) on breast cancer screening, published in the January issue of the Journal of the American College of Radiology (JACR), state that breast cancer screening should begin at age 40 and earlier in high-risk patients. The recommendations also suggest appropriate utilization of medical imaging modalities such as mammography, magnetic resonance imaging (MRI), and ultrasound for breast cancer screening.

5 Jan 2010

Trends in QALYs lost due to smoking and obesity

As the US population becomes increasingly obese while smoking rates continue to decline, obesity has become an equal, if not greater, contributor to the burden of disease and shortening of healthy life in comparison to smoking.

5 Jan 2010

Study shows low postoperative mortality rates after hip and knee replacement surgeries

Total hip and total knee replacement surgeries are highly successful and very common procedures for people experiencing pain associated with degenerative joints.

5 Jan 2010

Study examines relationship between parental vaccine refusal and risk of varicella infection in children

Children of parents who refuse vaccines are nine times more likely to get chickenpox compared to fully immunized children, according to a new study led by a vaccine research team at Kaiser Permanente Colorado's Institute for Health Research.

5 Jan 2010

Presence of Streptococcus pneumoniae could predict risk of severe disease in H1N1 pandemic influenza

The presence of the Streptococcus pneumoniae in samples that can be easily obtained in clinics and emergency rooms may predict risk of severe disease in H1N1 pandemic influenza.

31 Dec 2009

Tele-ICU system not linked to overall hospital mortality

Remote monitoring of patients in intensive care units (ICUs) was not associated with an overall improvement in the risk of death or length of stay in the ICU or hospital, according to a study in the December 23/30 issue of JAMA.

30 Dec 2009

Tarantula venom protein promising for MD

University at Buffalo biophysicists have found a protein in tarantula venom that shows promise as a potential therapy for muscular dystrophy (MD). They have formed a start-up biotech company in Buffalo -- Rose Pharmaceuticals -- to advance the drug to clinical trials.

30 Dec 2009

Advaxis reports 3-year survival data from its ADXS11-001 Phase I trial for cervical cancer

The Phase I trial of ADXS11-001, the lead vaccine candidate of Advaxis, Inc., the company that pioneered the live, attenuated Listeria monocytogenes (Lm) vaccine, has shown thirty-six (36) month survival in two (2) of the thirteen (13) evaluable patients treated with Advaxis’ therapeutic cancer vaccine, indicating the possibility of persistent immune protection, from only a two (2) dose initial regimen.

29 Dec 2009

Study suggests routine evaluation does not predict prostate cancer

On the heels of the American Cancer Society's recent controversial response to breast and prostate cancer screenings guidelines, a new study from the Mayo Clinic has emerged analyzing the correlation between prostate-specific antigen (PSA) levels and prostate size. The study discovered that routine annual evaluation of prostate growth does not predict the development of prostate cancer.

24 Dec 2009

New CIHI study highlights that Canada needs to retrieve more organs for transplants

The availability of donated organs in Canada rose by more than one-quarter (28%) over the past decade, but this increase is not keeping pace with demand. More than 1,000 Canadians donated organs in 2008, up from 812 in 1999, according to a new study released today by the Canadian Institute for Health Information (CIHI).

23 Dec 2009

Beta blockers may increase risk of anemia-induced adverse cardiovascular events

Routinely used to treat patients for heart attack or high blood pressure, beta blockers are known for their role in helping to protect the heart. A new study in the January issue of the journal Anesthesiology looks at the effects of beta blockers on surgical outcomes, revealing that the cardioprotective effects of the medication could be compromised by acute surgical anemia.

23 Dec 2009

ARCA biopharma submits Gencaro trial protocol for review under the FDA’s SPA process

ARCA biopharma, Inc. today announced that it has submitted a study protocol for review under the U.S. Food and Drug Administration’s (FDA) Special Protocol Assessment (SPA) process for the design of a clinical trial to assess the safety and efficacy of GencaroTM, in approximately 3,000 patients with chronic heart failure who have the genotype that appears to respond most favorably to Gencaro. Gencaro is the Company’s investigational, pharmacologically unique beta-blocker and mild vasodilator.

23 Dec 2009

Guardian Technologies International meets and presents SM TBDx to Indian healthcare officials

Tuberculosis (TB) continues to be a serious global pandemic health threat with more than 9 million new cases diagnosed annually. TB is a leading cause of mortality in India, killing nearly 1,000 people each day.

23 Dec 2009

Eritoran well tolerated in Phase II trial for severe sepsis

The investigational compound, eritoran tetrasodium ("eritoran," also known as E5564) appeared to be well tolerated in patients with severe sepsis in a Phase II trial published in the January issue of Critical Care Medicine, the official journal of the Society of Critical Care Medicine, the largest multiprofessional organization dedicated to ensuring excellence and consistency in the practice of critical care.

22 Dec 2009

Newly identified targets in treating inflammatory disorders of the gastrointestinal tract

Digestive-disease-associated mortality accounts for a major part of all deaths in Western societies and inflammatory diseases such as GI infections, viral hepatitis, GERD or cancers due to chronic inflammation have a tangible economic and social impact.

22 Dec 2009

AdvanDx receives FDA clearance for its 90 minutes PNA FISH protocol

AdvanDx today announced that it has received FDA 510(k) clearance for a fast, 90 minutes protocol for its E. coli/P. aeruginosa PNA FISH® and EK/P. aeruginosa PNA FISH® tests. The faster protocol reduces the PNA FISH turn-around time from the original 2.5 hours to 90 minutes by reducing PNA probe hybridization from 90 minutes to 30 minutes.

22 Dec 2009

Patients in dialysis centers demonstrated better clinical results after acquired by DaVita, study shows

DaVita Inc., a leading provider of kidney care services for those diagnosed with chronic kidney disease (CKD), today released a study finding patient outcomes in the company’s newly acquired centers showed dramatic improvements over the two years following their switch to DaVita® ownership.

22 Dec 2009

Abdominal surgery may increase risk of complications and death in older patients

The risk of complications and early death after commonly performed abdominal surgical procedures appears to be higher among older adults, according to a report in the December issue of Archives of Surgery, one of the JAMA/Archives journals.

22 Dec 2009

Mortality News and Research

Restoration of natural water flows can cause ecological harm

January issue of Chest presents new studies on COPD

SBI and ACR publish new recommendations on breast cancer screening

Trends in QALYs lost due to smoking and obesity

Study shows low postoperative mortality rates after hip and knee replacement surgeries

Study examines relationship between parental vaccine refusal and risk of varicella infection in children

Presence of Streptococcus pneumoniae could predict risk of severe disease in H1N1 pandemic influenza

Tele-ICU system not linked to overall hospital mortality

Tarantula venom protein promising for MD

Advaxis reports 3-year survival data from its ADXS11-001 Phase I trial for cervical cancer

Study suggests routine evaluation does not predict prostate cancer

New CIHI study highlights that Canada needs to retrieve more organs for transplants

Beta blockers may increase risk of anemia-induced adverse cardiovascular events

ARCA biopharma submits Gencaro trial protocol for review under the FDA’s SPA process

Guardian Technologies International meets and presents SM TBDx to Indian healthcare officials

Eritoran well tolerated in Phase II trial for severe sepsis

Newly identified targets in treating inflammatory disorders of the gastrointestinal tract

AdvanDx receives FDA clearance for its 90 minutes PNA FISH protocol

Patients in dialysis centers demonstrated better clinical results after acquired by DaVita, study shows

Abdominal surgery may increase risk of complications and death in older patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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