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Researchers use PET/CT for molecular imaging of the heart

For the first time, researchers used positron emission tomography (PET)/computed tomography (CT) for imaging the subcellar function of the heart - from its subcellular function to its morphologic appearance. The results of the study were reported at the Society of Nuclear Medicine's 52nd Annual Meeting June 18–22 in Toronto.

20 Jun 2005

Computer program that enhances the diagnostic accuracy of positron emission tomography (PET)

German scientists developed a computer program that enhances the diagnostic accuracy of positron emission tomography (PET) scans with Alzheimer's patients, opening the door for earlier treatment of this progressive brain disorder. Details of their findings were provided at the Society of Nuclear Medicine's 52nd Annual Meeting in Toronto.

20 Jun 2005

Inexpensive tests can be used to decide who needs HIV treatment in poor countries

Researchers from the Johns Hopkins Bloomberg School of Public Health, Centers for Disease Control and Prevention and the Chiang Mai University in Thailand, evaluated the ability of inexpensive biological markers, which are obtainable in resource-poor countries, to determine which HIV-infected patients are in the greatest need of antiretroviral therapy.

20 Jun 2005

New techniques use mitochondrial DNA as an early indicator for certain types of cancer

A pilot study at the National Institute of Standards and Technology (NIST), in support of the National Cancer Institute's Early Detection Research Network (EDRN), has validated the measurement accuracy of new techniques that use mitochondrial DNA as an early indicator for certain types of cancer.

16 Jun 2005

Dartmouth Medical School collaboration in Tanzania may alter assumptions about the diagnosis of tuberculosis in HIV-infected people

New findings from a Dartmouth Medical School collaboration in Tanzania may alter assumptions about the diagnosis of tuberculosis in HIV-infected people, and prompt a major change in way TB testing is routinely done in the developing world.

15 Jun 2005

New genetic test may detect risk of malignant hyperthermia (MH) from anesthesia

A rare but potentially life-threatening inherited condition called malignant hyperthermia (MH) may strike surgical patients who receive common drugs for general anesthesia.

14 Jun 2005

Research urges a new approach to cancer detection

A few years ago, Medhat Osman, M.D., Ph.D., had a patient who was scanned due to a suspicion of lung cancer using positron emission tomography (PET) and computer tomography (CT) technology. The scan came back negative, but the patient then complained of a problem with his leg.

14 Jun 2005

Two common gene variations are associated with the risk for developing chronic kidney disease

Two common gene variations are associated with the risk for developing chronic kidney disease, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions. One variant increases risk and the other decreases risk with a similar effect in whites, African-Americans, diabetic and non-diabetic individuals.

14 Jun 2005

New genetic test may detect risk of rare complication from anesthesia

A rare but potentially life- threatening inherited condition called malignant hyperthermia (MH) may strike surgical patients who receive common drugs for general anesthesia.

14 Jun 2005

Patients with newly diagnosed type 2 diabetes should be screened for retinopathy

Diabetic retinopathy has been found in nearly 8 percent of pre-diabetic participants in the Diabetes Prevention Program (DPP), according to a report presented today at the American Diabetes Association's 65th Annual Scientific Sessions.

12 Jun 2005

Genetic variations predispose Mexican Americans to insulin resistance

Although numerous studies have shown that low-grade inflammation is linked to heart disease and diabetes, more recent studies have shown that inflammation plays a role in insulin resistance, a syndrome that leads to diabetes and heart disease and affects about one in four adults in the United States.

12 Jun 2005

Link between PKC enzyme and kidney disease in diabetes confirmed

Researchers at Joslin Diabetes Center have investigated PKC-beta - a critical enzyme implicated in the devastating complications of type 1 and type 2 diabetes - for more than two decades.

12 Jun 2005

Link between hyperglycemia (high blood glucose), overexpression of PKC-beta 2 and kidney disease

Scientists at Joslin Diabetes Center have investigated PKC-beta -- a critical enzyme implicated in the devastating complications of type 1 and type 2 diabetes -- for more than two decades.

10 Jun 2005

Finding could provide targets for diagnosis, prognosis, therapy of prostate cancer

Researchers led by Dr. Shiv Srivastava from the Center for Prostate Disease Research (CPDR), Uniformed Services University of the Health Sciences (USU), report the groundbreaking discovery of the ETS-Related Gene (ERG) as one of the frequent proto-oncogene overexpressions in prostate cancer cells.

10 Jun 2005

Digital mammography no better than traditional film X-rays in the ability to detect cases of breast cancer

Digital mammography provides no clear-cut improvements over traditional film X-rays in the ability to detect cases of breast cancer, says a new technology assessment report. The technology does, however, offer other benefits, including slightly lower radiation doses for patients, that may prompt its increasing use despite its much higher costs.

10 Jun 2005

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

The human body has its own defense against brain aging: the innate immune system, which helps to clean the brain of amyloid-beta waste products. However, UCLA researchers discovered that some patients with Alzheimer’s disease have an immune defect making it difficult to clean away these wastes.

From MP Biomedicals, LLC 10 Jun 2005

Pillcam enables Jefferson Physicians to diagnose diseases of esophagus without using endoscope

Most digestive disease specialists will tell you that patients would rather suffer from heartburn and other diseases of the upper GI system than undergo a very effective but also potentially uncomfortable and relatively invasive procedure to diagnose their problem.

9 Jun 2005

New start-up to market test that predicts heart attack risk

PrognostiX, a start-up company based on Cleveland Clinic technology, has received approval from the U.S. Food and Drug Administration to begin selling a diagnostic test capable of identifying patients who are in imminent danger of heart attack or death.

9 Jun 2005

Multisequential MRI approach improves heart inflammation diagnosis

A multisequential approach to cardiovascular magnetic resonance scans that highlight different aspects of heart structure and function may offer a better and safer way to identify potentially deadly inflammation of the heart muscle, according to a new study (PDF) in the June 7, 2005, issue of the Journal of the American College of Cardiology.

9 Jun 2005

New study shows tiny RNAs intimately associated with cancer

In discoveries that may open a new chapter in understanding and diagnosing cancer, Howard Hughes Medical Institute (HHMI) investigators and their colleagues have established that tiny microRNAs provide a novel genetic route to the initiation of some forms of cancer.

9 Jun 2005

Diagnostic News and Research

Researchers use PET/CT for molecular imaging of the heart

Computer program that enhances the diagnostic accuracy of positron emission tomography (PET)

Inexpensive tests can be used to decide who needs HIV treatment in poor countries

New techniques use mitochondrial DNA as an early indicator for certain types of cancer

Dartmouth Medical School collaboration in Tanzania may alter assumptions about the diagnosis of tuberculosis in HIV-infected people

New genetic test may detect risk of malignant hyperthermia (MH) from anesthesia

Research urges a new approach to cancer detection

Two common gene variations are associated with the risk for developing chronic kidney disease

New genetic test may detect risk of rare complication from anesthesia

Patients with newly diagnosed type 2 diabetes should be screened for retinopathy

Genetic variations predispose Mexican Americans to insulin resistance

Link between PKC enzyme and kidney disease in diabetes confirmed

Link between hyperglycemia (high blood glucose), overexpression of PKC-beta 2 and kidney disease

Finding could provide targets for diagnosis, prognosis, therapy of prostate cancer

Digital mammography no better than traditional film X-rays in the ability to detect cases of breast cancer

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

Pillcam enables Jefferson Physicians to diagnose diseases of esophagus without using endoscope

New start-up to market test that predicts heart attack risk

Multisequential MRI approach improves heart inflammation diagnosis

New study shows tiny RNAs intimately associated with cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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