Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

MicroRNA dysregulation has critical impacts on development, inflammation and cancer development

Oncotarget Volume 11, Issue 10 reported that dysregulation of noncoding micro RNA molecules has been associated with immune cell activation in the context of Helicobacter pylori-induced gastric inflammation as well as carcinogenesis, but also with downregulation of mismatch repair genes, and may interfere with immune checkpoint proteins that lead to the overexpression of antigens on gastric tumor cells.

13 Mar 2020

Characterization of DNAm status of MMPs and TIMPs in atheromatous plaques

Oncotarget Volume 11, Issue 10 reported that the statistically associated Cp G sites were analyzed in blood samples from two separate atherothrombotic stroke cohorts, ischemic stroke-cohort 1: 37 atherothrombotic patients and 6 controls, ischemic stroke-cohort 2: 80 atherothrombotic patients and 184 controls.

13 Mar 2020

SPRK1 enzyme plays role in reorganizing the paternal genome during fertilization

A sperm enters an egg, an embryo develops and eventually a baby is born. But back up a second -- how does the mother's half-genome actually merge with the father's half-genome to form one new human genome?

13 Mar 2020

UC Riverside biochemist and Atomwise form new joint venture

Over the past few years, biochemist John Jefferson Perry at the University of California, Riverside, has collaborated on a number of projects with Atomwise Inc., a company that uses artificial intelligence, or AI, for drug discovery.

13 Mar 2020

Lower-salt processed turkey wins blind sensory test over full-salt option

University of Massachusetts Amherst food scientists produced a lower-salt processed turkey that consumers in a blind sensory test preferred to a full-salt version, according to a study published in the international journal LWT-Food Science and Technology.

13 Mar 2020

Tooth-enamel protein discovered in the eyes of people with dry AMD

A protein that normally deposits mineralized calcium in tooth enamel may also be responsible for calcium deposits in the back of the eye in people with dry age-related macular degeneration, according to a study from researchers at the National Eye Institute.

13 Mar 2020

NCAM2 protein is a vital factor in the formation of cerebral cortex, neuronal morphogenesis

The molecule NCAM2, a glycoprotein from the superfamily of immunoglobulins, is a vital factor in the formation of the cerebral cortex, neuronal morphogenesis and formation of neuronal circuits in the brain, as stated in the new study published in the journal Cerebral Cortex.

13 Mar 2020

DeNovix becomes sponsor at Tufts Launchpad BioLabs

DeNovix Inc.

From DeNovix Inc. 13 Mar 2020

NTHU research team develops new treatment for Parkinson’s disease

Ultrasound is widely used for conducting physical examinations, and plans are underway for expanding its application to the treatment of Parkinson's disease, dementia, and diabetes.

12 Mar 2020

Prize-winning research offers a promising approach to improve regenerative medicine

Joana Neves is the 2019 grand prize winner of the Sartorius & Science Prize for Regenerative Medicine & Cell Therapy, for work that offers a promising approach to improve the outcome of regenerative stem cell-based therapies aimed at delaying age-related degenerative diseases.

12 Mar 2020

Protective brain-cell housekeeping mechanism may also be involved in regulating sleep

An important biological mechanism that is thought to protect brain cells from neurodegenerative diseases such as Alzheimer's and Parkinson's may also be involved in regulating sleep, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

12 Mar 2020

Aspergillus molds induce asthma by first attacking the lung's protective barrier

University of Wisconsin-Madison researchers have identified a new way that common Aspergillus molds can induce asthma, by first attacking the protective tissue barrier deep in the lungs.

12 Mar 2020

Fruit flies provide insight on ACOX1-related neurodegenerative disorders

A study led by researchers at Baylor College of Medicine reports that a hyperactive variant of enzyme ACOX1 produces elevated levels of toxic reactive oxygen species (ROS) and causes a previously unidentified late-onset neurodegenerative disorder.

12 Mar 2020

No evidence of a link between surgery with anesthesia and Alzheimer's disease

Older adults who have surgery with general anesthesia may experience a modest acceleration of cognitive decline, even years later. But there's no evidence of a link to Alzheimer's disease, according to new research from Mayo Clinic.

12 Mar 2020

Scientists identify genes involved in the development of diabetic kidney disease

By analyzing samples from hundreds of Finns with diabetes, scientists have identified genes, and the proteins they encode, that could be involved in the development of diabetic kidney disease.

12 Mar 2020

Understanding how cancer cells interact and collaborate to metastasize

Cancer cells are known to migrate and collaborate to form networks that function as conduits providing access to nutrients and blood vessels.

12 Mar 2020

Researchers uncover clues to how statins kill cancer cells

More than 35 million Americans take statin drugs daily to lower their blood cholesterol levels. Now, in experiments with human cells in the laboratory, researchers at Johns Hopkins Medicine have added to growing evidence that the ubiquitous drug may kill cancer cells and have uncovered clues to how they do it.

12 Mar 2020

Virtual reality becomes a drug design tool

A new study published in March 2020 in the journal PLOS ONE shows the use of virtual reality (VR) as a powerful tool to create next-generation therapeutics. The focus is on the ability of VR to simulate the way commonly used drugs act on the cells at the molecular level, which enables innovation to improve the mechanism of action or to use alternate mechanisms.

11 Mar 2020

Potential targets for immune responses to novel coronavirus identified

Within two months, SARS-CoV-2, a previously unknown coronavirus, has raced around globe, infecting over a 100,000 people with numbers continuing to rise quickly.

11 Mar 2020