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Researchers discover how Sonic hedgehog gene controls brain development

University of Pennsylvania School of Medicine researchers have discovered how the expression of the Sonic hedgehog gene is regulated during brain development and how mutations that alter this process cause brain malformations. The results appear online this month in Nature Genetics.

28 Oct 2008

Universal test for genetic diseases in unborn children in the pipeline

A team of British scientists have developed a ground-breaking new test to screen for genetic diseases in unborn children.

27 Oct 2008

5 things you should know about stem cell research

In just a few weeks, Michigan voters will have an important decision to make when casting their ballots.

13 Oct 2008

Landmark study unlocks stem cell, DNA secrets to speed therapies

In a groundbreaking study led by an eminent molecular biologist at Florida State University, researchers have discovered that as embryonic stem cells turn into different cell types, there are dramatic corresponding changes to the order in which DNA is replicated and reorganized.

12 Oct 2008

Testicles may be a source of stem cells

A team of researchers from Britain and Germany have found that a man's testicles may be a source of stem cells.

12 Oct 2008

Antidepressants can affect male fertility

Researchers in the United States have linked commonly used antidepressants to a reduction in some men's fertility.

25 Sep 2008

Prostate cancer genes behave like those in embryo

Gene activity in prostate cancer is reminiscent of that in the developing fetal prostate, providing further evidence that all cancers are not equal, Johns Hopkins researchers report. The finding could help scientists investigate how to manipulate the genetic program to fight a disease whose biology remains poorly understood despite more than half a century of investigation.

16 Sep 2008

A third of miscarriages preventable with steroid treatment

A conference in Liverpool in the UK has heard how some women who have suffered repeated miscarriages or failed IVF treatments may be helped to become mothers by taking a course of steroids.

10 Sep 2008

Single embryo advice to IVF clinics will reduce the number of multiple births

Experts in the UK are advising that wherever possible, only one embryo per IVF cycle should be transferred in order to cut the rate of multiple births.

3 Sep 2008

Researchers find genetic proof on how osteoarthritis destroys cartilage

A team of orthopaedic researchers has found definitive, genetic proof of how the most common form of arthritis destroys joint cartilage in nearly 21 million aging Americans, according to a study published online Sept. 2 in the Journal of Bone and Mineral Research. The findings serve as an important foundation for the design of new treatments for osteoarthritis (OA), researchers said.

2 Sep 2008

Discovery of tumour growth enzyme could lead to new cancer drugs

Scientists say a landmark study has revealed an enzyme which is vital to the growth of many cancers.

1 Sep 2008

Transformation of ordinary cells into insulin-makers improves symptoms of diabetes

Scientists in the U.S. have successfully transformed ordinary cells into insulin-producing cells in a living mouse and thereby improved the symptoms of diabetes.

28 Aug 2008

Scientists identify microRNA that controls blood vessel development - therapeutic target for a number of diseases

Scientists from the Gladstone Institute of Cardiovascular Disease (GICD) and UCSF have identified a key regulatory factor that controls development of the human vascular system, the extensive network of arteries, veins, and capillaries that allow blood to reach all tissues and organs.

11 Aug 2008

Scientists identify possible cause of endometriosis

Scientists at the University of Liverpool have identified an enzyme that could be responsible for a condition called endometriosis - the most common cause of pelvic pain in women.

5 Aug 2008

Binge drinking in pregnancy increases risk of oral clefts in offspring

A new study by researchers at the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, shows that pregnant women who binge drink early in their pregnancy increase the likelihood that their babies will be born with oral clefts.

31 Jul 2008

Notch protein helps human embryonic stem cells 'decide' their own fate

Researchers at Johns Hopkins have discovered that the Notch protein helps human embryonic stem cells 'decide' their own fate, a finding which may eventually be useful in programming cells for the development of stem cell therapies. Their results are reported in the May 2008 issue of Cell Stem Cell.

22 Jul 2008

Discovery of cells for spinal-cord repair

A researcher at MIT's Picower Institute for Learning and Memory has pinpointed stem cells within the spinal cord that, if persuaded to differentiate into more healing cells and fewer scarring cells following an injury, may lead to a new, non-surgical treatment for debilitating spinal-cord injuries.

22 Jul 2008

New technology revolutionizing drug discovery

The National Science Foundation has awarded Weill Cornell Medical College researcher Dr. Scott Blanchard its prestigious Career Award, recognizing his groundbreaking work in cell biology -- work that is poised to revolutionize research for the next generation of young scientists.

15 Jul 2008

An inflamed response

Paul Martin, Professor of Cell Biology in the University of Bristol Departments of Physiology and Pharmacology, and Biochemistry, talked to Cherry Lewis about the discovery made in his lab that speeds up wound healing and reduces the size of the wound scar. She was interested not only in the discovery itself, but also in the processes and years of research that led up to it.

15 Jul 2008

Diabetes effects sperm quality

Diabetes in men has a direct effect on fertility, a scientist told the 24th annual conference of the European Society of Human Reproduction and Embryology today (Wednesday 9 July).

9 Jul 2008