Genes News and Research

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Harmless genetic variations may team up to increase risk of schizophrenia, find researchers

Using a novel method of analyzing genetic variations in families, researchers at Johns Hopkins have found that individually harmless genetic variations affecting related biochemical processes may team up to increase the risk of schizophrenia.

29 May 2013

More evidence of high oxidative stress levels found in Down syndrome neurons

Down syndrome, the most common genetic form of intellectual disability, results from an extra copy of one chromosome. Although people with Down syndrome experience intellectual difficulties and other problems, scientists have had trouble identifying why that extra chromosome causes such widespread effects.

28 May 2013

Researchers identify mutations in new genes that might be associated with ALS disease

Researchers at the Stanford University School of Medicine have identified mutations in several new genes that might be associated with the development of spontaneously occurring cases of the neurodegenerative disease known as amyotrophic lateral sclerosis, or ALS.

27 May 2013

Scientists report new way of tackling cancer and predicting tumor virulence

A new way of tackling cancer and predicting tumor virulence are has been reported by a team of scientists from the Institut Albert Bonniot de Grenoble including researchers from CNRS, Inserm and Université Joseph Fourier, in collaboration with clinical physicians and anatomopathologists from the CHU de Grenoble, with the support of the Institut National du Cancer, the Ligue Nationale Contre le Cancer and the Fondation ARC pour la Recherche sur le Cancer.

26 May 2013

New therapeutic targets for infantile myofibromatosis

Two mutations central to the development of infantile myofibromatosis -a disorder characterized by multiple tumors involving the skin, bone, and soft tissue-may provide new therapeutic targets, according to researchers from the Icahn School of Medicine at Mount Sinai.

26 May 2013

Research: Anti-cancer drug tested as possible treatment for Alzheimer's disease proved ineffective

An anti-cancer drug about to be tested in a clinical trial by a biomedical company in Ohio as a possible treatment for Alzheimer's disease has failed to work with the same type of brain plaques that plague Alzheimer's patients, according to results of a study by University of Florida researchers.

24 May 2013

Study finds differences in the brains of patients suffering from psychiatric diseases

Studying the networks of connections in the brains of people affected by schizophrenia, bipolar disease or depression has allowed Dr. Peter Williamson, from Western University, to gain a better understanding of the biological basis of these important diseases.

24 May 2013

New technique may help develop genetic thermometer to assess patients’ health

On May 22, JoVE will publish details of a technique to measure the health of human genetic material in relation to a patient-s age. The method is demonstrated by the laboratory of Dr. Gil Atzmon at New York-s Albert Einstein College of Medicine.

24 May 2013

TSRI scientists devise new technique to find therapeutic antibodies

Scientists at The Scripps Research Institute have devised a powerful new technique for finding antibodies that have a desired biological effect. Antibodies, which can bind to billions of distinct targets, are already used in many of the world's best-selling medicines, diagnostics and laboratory reagents.

24 May 2013

Potential new treatment approaches for liver diseases

By discovering the new mechanism by which estrogen suppresses lipid synthesis in the liver, UC Irvine endocrinologists have revealed a potential new approach toward treating certain liver diseases.

24 May 2013

New approach to genetic engineering reduces time and effort needed to insert genes into bacteria

A new, streamlined approach to genetic engineering drastically reduces the time and effort needed to insert new genes into bacteria, the workhorses of biotechnology, scientists are reporting.

24 May 2013

Promising approach to prevent emergence of drug-resistant forms of cancer

Re-routing anti-cancer drugs to the "power plants" that make energy to keep cells alive is a promising but long-neglected approach to preventing emergence of the drug-resistant forms of cancer - source of a serious medical problem, scientists are reporting.

24 May 2013

Researchers explore targeted therapies for prostate cancer

Are certain drugs more effective against some types of prostate cancers than others? Researchers know that not all therapies work for all patients – the next question is to figure out how to match the right treatments with the right patients.

24 May 2013

Wisconsin scientists synthesize potent compounds to curb bacteria that cause staph infections

In an age when microbial pathogens are growing increasingly resistant to the conventional antibiotics used to tamp down infection, a team of Wisconsin scientists has synthesized a potent new class of compounds capable of curbing the bacteria that cause staph infections.

24 May 2013

Cenix BioScience, Debiopharm partner to develop novel therapeutic drug candidates

Cenix BioScience, a leading preclinical contract research provider and technology developer specialized in RNAi-, miRNA- and high content-driven pharmacology, and Debiopharm Group, a Swiss-based global biopharmaceutical group of companies with a focus on the development of prescription drugs that target unmet medical needs, including oncology and companion diagnostics, today announced that they have signed a research agreement to support Debiopharm in its ongoing efforts to develop novel therapeutic drug candidates.

23 May 2013

The Immortality Project awards $2.3M to study near-death experiences, beliefs in afterlife

Phenomena related to near-death experiences, immortality in virtual reality, and genes that prevent a species of freshwater hydra from aging are among the first research proposals funded by The Immortality Project at the University of California, Riverside.

23 May 2013

Viewpoints: Mass. experience may not be true test for national health law; 'Dishonest' campaign by medical device makers

Massachusetts is often held up as a window into America's health insurance future, because it embarked on what came to be called the Romneycare reform six years ago. Like the Affordable Care Act provisions going into effect nationwide next year, Romneycare aimed to increase the fraction of the population with health insurance by imposing mandates on employers and employees and by subsidizing health insurance plans for middle-class families without employer plans.

23 May 2013

NIH-funded study raises hope for recovery of some adult patients with brain disorder

Scientists have reversed behavioral and brain abnormalities in adult mice that resemble some features of schizophrenia by restoring normal expression to a suspect gene that is over-expressed in humans with the illness.

23 May 2013

Viewpoints: Slowing health costs; What causes genetic testing to be so expensive; Iowa governor offers Medicaid supports a 'glimmer of hope'

We have done it. We have decreased the increase in the cost of healthcare. ... Is this decline the desperately needed bend in the healthcare cost curve or just the impact of the depressed economy? ... A slower growth of healthcare cost would mean less burden on the individual family, freeing that family to invest in and live a higher quality of life.

22 May 2013

Rice University computational study tracks regulatory mechanisms of E. coli cells

Environment is not the only factor in shaping regulatory patterns -- and it might not even be the primary factor, according to a new Rice University study that looks at how cells' protein networks relate to a bacteria's genome.

22 May 2013

Genes News and Research

Harmless genetic variations may team up to increase risk of schizophrenia, find researchers

More evidence of high oxidative stress levels found in Down syndrome neurons

Researchers identify mutations in new genes that might be associated with ALS disease

Scientists report new way of tackling cancer and predicting tumor virulence

New therapeutic targets for infantile myofibromatosis

Research: Anti-cancer drug tested as possible treatment for Alzheimer's disease proved ineffective

Study finds differences in the brains of patients suffering from psychiatric diseases

New technique may help develop genetic thermometer to assess patients’ health

TSRI scientists devise new technique to find therapeutic antibodies

Potential new treatment approaches for liver diseases

New approach to genetic engineering reduces time and effort needed to insert genes into bacteria

Promising approach to prevent emergence of drug-resistant forms of cancer

Researchers explore targeted therapies for prostate cancer

Wisconsin scientists synthesize potent compounds to curb bacteria that cause staph infections

Cenix BioScience, Debiopharm partner to develop novel therapeutic drug candidates

The Immortality Project awards $2.3M to study near-death experiences, beliefs in afterlife

Viewpoints: Mass. experience may not be true test for national health law; 'Dishonest' campaign by medical device makers

NIH-funded study raises hope for recovery of some adult patients with brain disorder

Viewpoints: Slowing health costs; What causes genetic testing to be so expensive; Iowa governor offers Medicaid supports a 'glimmer of hope'

Rice University computational study tracks regulatory mechanisms of E. coli cells

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