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Caltech biologists show that microRNA-146a protects stem cells during inflammation

When infections occur in the body, stem cells in the blood often jump into action by multiplying and differentiating into mature immune cells that can fight off illness. But repeated infections and inflammation can deplete these cell populations, potentially leading to the development of serious blood conditions such as cancer.

22 May 2013

Nearly 35% of Mexican young adults may have genetic predisposition for obesity, says U of I scientist

As many as 35 percent of Mexican young adults may have a genetic predisposition for obesity, said a University of Illinois scientist who conducted a study at the Universidad Aut-noma de San Luis Potosί.

22 May 2013

Nutritional supplement improves functioning of genes involved in degenerative brain disorders

Widely available in pharmacies and health stores, phosphatidylserine is a natural food supplement produced from beef, oysters, and soy. Proven to improve cognition and slow memory loss, it's a popular treatment for older people experiencing memory impairment.

22 May 2013

PGDx to identify novel kinase targets in collaboration with Blueprint Medicines

Personal Genome Diagnostics Inc., today announced that it will use its proprietary methodologies and expertise in genomic analysis of defined cancer subtypes to identify novel kinase targets in collaboration with Blueprint Medicines.

21 May 2013

Stronger epigenetic changes in estrogen responsive genes linked to postpartum depression

The epigenetic modifications, which alter the way genes function without changing the underlying DNA sequence, can apparently be detected in the blood of pregnant women during any trimester, potentially providing a simple way to foretell depression in the weeks after giving birth, and an opportunity to intervene before symptoms become debilitating.

21 May 2013

Researchers say that receiving cancer radiation therapy late in the day may minimize hair loss

Discovering that mouse hair has a circadian clock - a 24-hour cycle of growth followed by restorative repair - researchers suspect that hair loss in humans from toxic cancer radiotherapy and chemotherapy might be minimized if these treatments are given late in the day.

21 May 2013

Researchers develop new mouse model to discover gene pathways that drive MPNST

University of Minnesota Medical School researchers from the Masonic Cancer Center, University of Minnesota, in partnership with the University's Brain Tumor Program, have developed a new mouse model of malignant peripheral nerve sheath tumors that allow them to discover new genes and gene pathways driving this type of cancer.

21 May 2013

Researchers examine how BRD4 contributes to sustained presence of NF-kappa B in cancer cells

In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.

20 May 2013

Measuring genetic diversity within tumor predicts outcomes of patients with head and neck cancer

A new measure of the heterogeneity - the variety of genetic mutations - of cells within a tumor appears to predict treatment outcomes of patients with the most common type of head and neck cancer.

20 May 2013

Innovative X-ray method advances new treatments for genetic diseases

An international team of scientists using a new X-ray method recorded the internal structure and cell movement inside a living frog embryo in greater detail than ever before.

18 May 2013

Authors urge importance of patients' rights in genome sequencing

Informed consent is the backbone of patient care. Genetic testing has long required patient consent and patients have had a "right not to know" the results. However, as 21st century medicine now begins to use the tools of genome sequencing, an enormous debate has erupted over whether patients' rights will continue in an era of medical genomics.

18 May 2013

AGA announces new grant to study relationship between gut microbiota, digestive disease

The AGA Research Foundation announced a new grant that intends to stimulate research into the relationship between the gut microbiota, one of today's most exciting areas of science, and digestive health and disease.

18 May 2013

Women with family history of cancer need to have proper counseling, testing

In the wake of actress Angelina Jolie's public announcement that she recently underwent a preventive double mastectomy, Loma Linda University Medical Center urges women with a family history of cancer to have proper counseling and testing, if indicated, to see if they are at similar risk.

17 May 2013

Weekend reading: Volunteers in the battle with heart disease; Psychiatry without medication; Owning your genes

Psychiatrists who take time with their patients are not the norm. It's not because others don't care. Rather the system rewards efficiency, not empathy.

17 May 2013

Protein processing breakdown in endoplasmic reticulum

With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds substantially to the story by reporting the discovery of a molecular chain of events in the brains of obese rats that undermined their ability to suppress appetite and to increase calorie burning.

17 May 2013

Researchers use new analysis method to determine genes that result in cell death

Lethal and rescuer genes are defined as genes that when inactivated result in cell death or enhanced cell growth, respectively. The ability to identify these genes in large-scale automated screening campaigns could lead to the discovery of valuable new drug targets.

17 May 2013

Northwestern University scientists identify gene important to morning wake-up call

Northwestern University scientists have shown a gene involved in neurodegenerative disease also plays a critical role in the proper function of the circadian clock.

17 May 2013

Scientists identify 4 genes in baboons that influence levels of bad cholesterol

Scientists at the Texas Biomedical Research Institute in San Antonio have identified four genes in baboons that influence levels of "bad" cholesterol. This discovery could lead to the development of new drugs to reduce the risk of heart disease.

17 May 2013

Study provides new evidence that genetic risk for schizophrenia associated with lower IQ

The relationship between the heritable risk for schizophrenia and low intelligence has not been clear. Schizophrenia is commonly associated with cognitive impairments that may cause functional disability. There are clues that reduced IQ may be linked to the risk for developing schizophrenia.

17 May 2013

Viewpoints: Controversy taints IRS efforts on health law; Another chance to 'gut' the overhaul in the courts; Salt wrongly accused

Even as the politicized tax enforcement scandal expands, the Internal Revenue Service continues to expand its political powers thanks to the Affordable Care Act. A larger government always creates more openings for abuse, as Americans will learn when the IRS starts auditing their health care in addition to their 1040 next year (5/14).

16 May 2013

Genes News and Research

Caltech biologists show that microRNA-146a protects stem cells during inflammation

Nearly 35% of Mexican young adults may have genetic predisposition for obesity, says U of I scientist

Nutritional supplement improves functioning of genes involved in degenerative brain disorders

PGDx to identify novel kinase targets in collaboration with Blueprint Medicines

Stronger epigenetic changes in estrogen responsive genes linked to postpartum depression

Researchers say that receiving cancer radiation therapy late in the day may minimize hair loss

Researchers develop new mouse model to discover gene pathways that drive MPNST

Researchers examine how BRD4 contributes to sustained presence of NF-kappa B in cancer cells

Measuring genetic diversity within tumor predicts outcomes of patients with head and neck cancer

Innovative X-ray method advances new treatments for genetic diseases

Authors urge importance of patients' rights in genome sequencing

AGA announces new grant to study relationship between gut microbiota, digestive disease

Women with family history of cancer need to have proper counseling, testing

Weekend reading: Volunteers in the battle with heart disease; Psychiatry without medication; Owning your genes

Protein processing breakdown in endoplasmic reticulum

Researchers use new analysis method to determine genes that result in cell death

Northwestern University scientists identify gene important to morning wake-up call

Scientists identify 4 genes in baboons that influence levels of bad cholesterol

Study provides new evidence that genetic risk for schizophrenia associated with lower IQ

Viewpoints: Controversy taints IRS efforts on health law; Another chance to 'gut' the overhaul in the courts; Salt wrongly accused

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