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Investigational treatment for ALS passes early phase clinical trial for safety

An investigational treatment for an inherited form of Lou Gehrig's disease has passed an early phase clinical trial for safety, researchers at Washington University School of Medicine in St. Louis and Massachusetts General Hospital report.

24 Apr 2013

University of Leicester study investigates early detection of pancreatic cancer

Pioneering research to investigate whether pancreatic cancer can be detected early through a blood test is to be spearheaded by the University of Leicester thanks to new funding provided by Hope Against Cancer.

24 Apr 2013

Research shows sophisticated genetic circuits allow individual bacterium to act on its own

Individual freedom and social responsibility may sound like humanistic concepts, but an investigation of the genetic circuitry of bacteria suggests that even the simplest creatures can make difficult choices that strike a balance between selflessness and selfishness.

23 Apr 2013

iQBS researchers discover three unique genetic variations that influence body size, obesity in African ancestry

Researchers from Dartmouth's Institute for Quantitative Biomedical Sciences (iQBS) and the Center for Genomic Medicine have helped to discover three unique genetic variations that influence body size and obesity in men and women of African ancestry.

23 Apr 2013

Animal models of Huntington's disease allow better insights into disease's genetics

Scientific progress in Huntington's disease (HD) relies upon the availability of appropriate animal models that enable insights into the disease's genetics and/or pathophysiology.

23 Apr 2013

Researchers find deficiency in anti-tumor protein can delay DNA repair after radiation treatment

Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression of two enzymes (JMJD2b and SUV39H1) that control the folding of DNA.

23 Apr 2013

Experimental drug can reduce breast-cancer aggressiveness, restore drug-sensitivity

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) suggests that an unusual experimental drug can reduce breast-cancer aggressiveness, reverse resistance to the drug fulvestrant and perhaps improve the effectiveness of other breast-cancer drugs.

23 Apr 2013

Exposure to chemical pesticide has impacts that span multiple generations, say researchers

North Carolina State University researchers studying aquatic organisms called Daphnia have found that exposure to a chemical pesticide has impacts that span multiple generations - causing the so-called "water fleas" to produce more male offspring, and causing reproductive problems in female offspring.

23 Apr 2013

Researchers find tumors with ALK rearrangements can harbor additional mutations

The identification of potentially targetable kinase mutations has been an exciting advancement in lung cancer treatment.

23 Apr 2013

GeneCapture developing new device with one-hour pathogen testing capabilities

A company hatched as a partnership between The University of Alabama in Huntsville and chemical engineering professor Dr. Krishnan Chittur is in the design phase for a device that can provide physicians one-hour pathogen testing capabilities.

23 Apr 2013

Scientists identify new genes that offer potential treatment options for childhood arthritis

Scientists from The University of Manchester have identified 14 new genes which could have important consequences for future treatments of childhood arthritis.

From The University of Manchester 23 Apr 2013

Findings open new possibilities for research, testing treatments to combat obesity

Joslin scientists report significant findings about the location, genetic expression and function of human brown adipose tissue and the generation of new BAT cells.

23 Apr 2013

Medical researchers race to find ways to use gene sequencing to fight cancer

Technology is quickly revamping medical care. The New York Times looks at the possible use of gene sequencing, while other news outlets examine apps and online tools that are helping Alzheimer's and autism caregivers.

23 Apr 2013

International team of researchers joins forces to decode genome of prehistoric fish

An enigmatic prehistoric fish has brought scientists at A*STAR's Institute of Molecular and Cell Biology (IMCB) together with researchers from all over the world to crack its genomic code.

22 Apr 2013

Loss or amplification of particular DNA regions contributes to the development of prostate cancer

A new analysis has found that the loss or amplification of particular DNA regions contributes to the development of prostate cancer, and that patients with two of these DNA changes have a high likelihood of dying from the disease.

22 Apr 2013

First Edition: April 22, 2013

Today's headlines include reports ranging from how state leaders are dealing with the consequences of rejecting the health law's Medicaid expansion to how pending immigration reform proposals could ease the nation's physician shortage.

22 Apr 2013

Advanced microscope reveals process where mutations lead to autism and other diseases

Using spinning disk microscopy on barely day-old zebra fish embryos, University of Oregon scientists have gained a new window on how synapse-building components move to worksites in the central nervous system.

22 Apr 2013

Study identifies potential drug targets that interfere with cancer metabolism

A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer.

22 Apr 2013

Monoclonal antibody inhibits tumor growth in angiosarcoma and breast cancer

A monoclonal antibody targeting a protein known as SFPR2 has been shown by researchers at the University of North Carolina to inhibit tumor growth in pre-clinical models of breast cancer and angiosarcoma.

20 Apr 2013

Shc plays key role in activating and controlling Erk

A protein which is intimately involved in cancer-promoting cell signaling also keeps a key component of the signaling pathway tied down and inactive, a team led by scientists from The University of Texas MD Anderson Cancer Center reports this week in Nature Structural Molecular Biology.

20 Apr 2013

Genes News and Research

Investigational treatment for ALS passes early phase clinical trial for safety

University of Leicester study investigates early detection of pancreatic cancer

Research shows sophisticated genetic circuits allow individual bacterium to act on its own

iQBS researchers discover three unique genetic variations that influence body size, obesity in African ancestry

Animal models of Huntington's disease allow better insights into disease's genetics

Researchers find deficiency in anti-tumor protein can delay DNA repair after radiation treatment

Experimental drug can reduce breast-cancer aggressiveness, restore drug-sensitivity

Exposure to chemical pesticide has impacts that span multiple generations, say researchers

Researchers find tumors with ALK rearrangements can harbor additional mutations

GeneCapture developing new device with one-hour pathogen testing capabilities

Scientists identify new genes that offer potential treatment options for childhood arthritis

Findings open new possibilities for research, testing treatments to combat obesity

Medical researchers race to find ways to use gene sequencing to fight cancer

International team of researchers joins forces to decode genome of prehistoric fish

Loss or amplification of particular DNA regions contributes to the development of prostate cancer

First Edition: April 22, 2013

Advanced microscope reveals process where mutations lead to autism and other diseases

Study identifies potential drug targets that interfere with cancer metabolism

Monoclonal antibody inhibits tumor growth in angiosarcoma and breast cancer

Shc plays key role in activating and controlling Erk

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