Genes News and Research

RSS

Study shows hsa-miR-146a overexpressed in most metastatic tumors

In order to kill, bladder cancer must metastasize, most commonly to the lung - what are the differences between bladder cancers that do and do not make this deadly transition? Research presented by the Director of the University of Colorado Cancer Center at the AACR Annual Meeting 2013 shows that one big difference is a little molecule known as hsa-miR-146a.

11 Apr 2013

Incidence of late-onset Alzheimer disease higher among African Americans

In a meta-analysis of data from nearly 6,000 African Americans, Alzheimer disease was significantly associated with a gene that have been weakly associated with Alzheimer disease in individuals of European ancestry, although additional studies are needed to determine risk estimates specific for African Americans, according to a study in the April 10 issue of JAMA, a Genomics theme issue.

11 Apr 2013

Study: microRNA is designed to stop proliferation of prostate cancer cells

The most recent in a series of studies from a team at the UC Davis Comprehensive Cancer Center has shown that a single molecule is at the heart of one of the most basic survival tactics of prostate cancer cells.

10 Apr 2013

Immunotherapy and epigenetics advancements presented by Ludwig at the American Association for Cancer Research

A dozen Ludwig scientists from around the world presented the latest advancements in basic and clinical cancer research at this week’s American Association for Cancer Research (AACR) Annual Meeting 2013. Progress in immunotherapy and epigenetics led the program with important diagnostic and treatment implications for emerging cancer therapy.

10 Apr 2013

Research: African-Americans with ABCA7 gene variant have double risk of developing AD

African-Americans with a variant of the ABCA7 gene have almost double the risk of developing late-onset Alzheimer's disease compared with African-Americans who lack the variant.

10 Apr 2013

Six2 homeoprotein causes breast cancer progression, say researchers

In results presented at the AACR Annual Meeting 2013, researchers from the University of Colorado Cancer Center show that the Six2 homeoprotein, while not involved in primary tumor growth, allows cells to detach from substrate and survive their transition through the bloodstream to faraway sites of metastasis.

10 Apr 2013

Phase I results show Rogosertib is well tolerated in patients with advanced solid tumors

Results of a phase 1 clinical trial reported at the American Association for Cancer Research (AACR) annual conference show that orally administered Rigosertib is well tolerated in patients with advanced solid tumors.

10 Apr 2013

Researchers use metagenomics to reconstruct genome sequence of Shiga-toxigenic Escherichia coli

Researchers have been able to reconstruct the genome sequence of an outbreak strain of Shiga-toxigenic Escherichia coli using metagenomics (the direct sequencing of DNA extracted from microbiologically complex samples), according to a study in the April 10 issue of JAMA, a Genomics theme issue.

10 Apr 2013

AACR recognizes UT MD Anderson professor for contributions to cancer research

Guillermina "Gigi" Lozano, Ph.D., chair and professor in the Department of Genetics at The University of Texas MD Anderson Cancer Center, is the recipient of the 16th annual Women in Cancer Research Charlotte Friend Memorial Lectureship awarded by The American Association for Cancer Research, recognizing her contributions to the field of cancer research and the advancement of women in science.

10 Apr 2013

Lynch syndrome and cancer risk: an interview with Prof. Ellen Kampman, Wageningen University

Lynch syndrome is one of the inherited cancer syndromes characterized by the development of colorectal cancer, endometrial cancer and other cancers at an early age.

10 Apr 2013

Researchers discover genetic variants of heart disorder in some cases of stillbirth

In a first-of-its-kind study, researchers from the United States and Europe discovered genetic mutations associated with long QT syndrome, a genetic abnormality in the heart's electrical system, in a small number of intrauterine fetal deaths, according to a study in the April 10 issue of the Journal of the American Medical Association.

10 Apr 2013

MD Anderson scientists demonstrate new way to restore tumor suppression

Tumor suppression, the family business of the sibling genes p53, p63 and p73, is undermined from within by the split personalities of p63 and p73, which each produce protein forms that not only block the work of the other two genes but also shut down its own cancer-stifling fraternal twin.

10 Apr 2013

CvergenX to develop radiosensitivity test to better radiation therapy decisions for patients with cancer

A molecular signature index technology that can lead to better radiation therapy decisions for patients with cancer is being developed into a reliable radiosensitivity test by CvergenX, Inc., an advanced cancer diagnostics company.

10 Apr 2013

Findings could help develop new ways to predict risks of tobacco-associated cancers

Believe it or not, while researchers have explored which genes are mutated in each type of tobacco-associated cancer, until now no one had thought to look across these types for common genes that might predict patient outcomes. Results presented at the AACR Annual Meeting 2013 show that in lung and bladder cancers, genes related to the regulation of the cell cycle are associated with poor patient outcomes.

10 Apr 2013

Gene variations can predispose people to chemotherapy-induced peripheral neuropathy

Seemingly benign differences in genetic code from one person to the next could influence who develops side effects to chemotherapy, a Mayo Clinic study has found.

10 Apr 2013

Multiple genes strongly contribute to risk for schizophrenia

Multiple genes contribute to risk for schizophrenia and appear to function in pathways related to transmission of signals in the brain and immunity, according to an international study led by Virginia Commonwealth University School of Pharmacy researchers.

10 Apr 2013

BRCA2 gene mutation carriers at greater risk for more advanced prostate cancer

Patients with prostate cancer and hereditary mutations in the BRCA2 gene have a worse prognosis and lower survival rates than do the rest of the patients with the disease.

10 Apr 2013

Mother's stress associated with development of pathologies related with obesity

The intrauterine environment plays an important role in the health of the offspring. Now, experts from the University of Navarra affirm that the mother's stress, due to socio-economic or psycho-social causes, is associated with the development of pathologies related with obesity.

10 Apr 2013

Nearly 50% of breast cancer patients at high risk of carrying BRCA mutation do not undergo genetic testing

Only 53 percent of newly diagnosed breast cancer patients who were at high risk of carrying a BRCA 1 or BRCA 2 mutation - based on age, diagnosis, and family history of breast or ovarian cancer - reported that their doctors urged them to be tested for the genes, according to a research team from the Perelman School of Medicine at the University of Pennsylvania.

9 Apr 2013

Newly discovered mouse viruses can pave the way for future progress in hepatitis research

Newly discovered mouse viruses could pave the way for future progress in hepatitis research, enabling scientists to study human disease and vaccines in the ultimate lab animal.

9 Apr 2013

Genes News and Research

Study shows hsa-miR-146a overexpressed in most metastatic tumors

Incidence of late-onset Alzheimer disease higher among African Americans

Study: microRNA is designed to stop proliferation of prostate cancer cells

Immunotherapy and epigenetics advancements presented by Ludwig at the American Association for Cancer Research

Research: African-Americans with ABCA7 gene variant have double risk of developing AD

Six2 homeoprotein causes breast cancer progression, say researchers

Phase I results show Rogosertib is well tolerated in patients with advanced solid tumors

Researchers use metagenomics to reconstruct genome sequence of Shiga-toxigenic Escherichia coli

AACR recognizes UT MD Anderson professor for contributions to cancer research

Lynch syndrome and cancer risk: an interview with Prof. Ellen Kampman, Wageningen University

Researchers discover genetic variants of heart disorder in some cases of stillbirth

MD Anderson scientists demonstrate new way to restore tumor suppression

CvergenX to develop radiosensitivity test to better radiation therapy decisions for patients with cancer

Findings could help develop new ways to predict risks of tobacco-associated cancers

Gene variations can predispose people to chemotherapy-induced peripheral neuropathy

Multiple genes strongly contribute to risk for schizophrenia

BRCA2 gene mutation carriers at greater risk for more advanced prostate cancer

Mother's stress associated with development of pathologies related with obesity

Nearly 50% of breast cancer patients at high risk of carrying BRCA mutation do not undergo genetic testing

Newly discovered mouse viruses can pave the way for future progress in hepatitis research

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics