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Monitoring patients' hydroxychloroquine blood levels can predict their clotting risk

The antimalarial drug hydroxychloroquine is frequently prescribed to treat symptoms of the autoimmune disease lupus. In addition to decreasing disease flares, the drug can also prevent blood clots, which are a major problem in individuals with lupus.

6 Jan 2021

New mathematical model proposes optimal treatment strategies for COVID-19

Getting control of COVID-19 will take more than widespread vaccination; it will also require a better understanding of why the disease causes no apparent symptoms in some people but leads to rapid multi-organ failure and death in others, as well as better insight into what treatments work best and for which patients.

5 Jan 2021

Study: Decreased activation of LEF1 gene disrupts ordinary neuronal function

Lithium is considered the gold standard for treating bipolar disorder (BD), but nearly 70 percent of people with BD don't respond to it.

5 Jan 2021

Scientist receives $1.37 million grant to advance metabolomics data

The National Institutes of Health (NIH) has awarded University of Massachusetts Amherst biostatistician Raji Balasubramanian a four-year, $1.37 million grant to advance the analysis of data from metabolomics research.

5 Jan 2021

Mid-term clinical trial results of two cell therapies for critical limb ischemia show similar outcomes

Mid-term results of the first clinical trial designed specifically to evaluate the safety and effectiveness of two cell therapies that are showing early promise in treating angiitis-induced critical limb ischemia were released today in STEM CELLS Translational Medicine.

5 Jan 2021

Groundbreaking research project shows how brain health can traverse generations

Your father's exercise routine may have made you smarter according to EU-funded researchers studying how lifestyle choices affect brain function and memory. The findings could lead to new treatments for neurodegenerative conditions such as Alzheimer's disease.

5 Jan 2021

Inhibition of blood clotting factor reduces the formation of brain metastases in mice

Brain metastases can only develop if cancer cells first exit the fine blood vessels and enter into the brain tissue.

5 Jan 2021

SARS-CoV-2 infected alveolar type-II lung cells show senescence

Using monoclonal antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and senescent markers, researchers provide evidence that virus-infected lung cells acquire characteristics of cellular senescence, which also leads to expression of proinflammatory cytokines.

5 Jan 2021

Heat treatment during chemotherapy is more effective at destroying cancer cells

Heating up cancer cells while targeting them with chemotherapy is a highly effective way of killing them, according to a new study led by UCL researchers.

5 Jan 2021

Biological imbalance found to be the link between gum and kidney disease

An imbalance of the body's oxygen producing free radicals and its antioxidant cells could be the reason why gum disease and chronic kidney disease affect each other, a new study led by the University of Birmingham has found.

5 Jan 2021

Many health plans now must cover full cost of expensive HIV prevention drugs

Ted Howard started taking Truvada a few years ago because he wanted to protect himself against HIV, the virus that causes AIDS. But the daily pill was so pricey he was seriously thinking about giving it up.

5 Jan 2021

$Prolactin triggers male refractory period, indicates study$

Prolactin triggers male refractory period, indicates study

If you type into a search engine - "why do men have to wait before having sex again?" - you will very quickly come across Prolactin. This little hormone is thought to be involved in hundreds of physiological processes in the body. Among them is the male post-ejaculatory refractory period. This period begins when a male ejaculates and ends when he recovers his sexual capacity.

4 Jan 2021

Routine eye imaging may provide clues to cognitive disorders in older people with type 1 diabetes

As they age, people with diabetes are more likely to develop Alzheimer's disease and other cognitive disorders than are people without diabetes.

4 Jan 2021

Research offers clues on why pregnancy may raise risk of organ transplant rejection

A research study at the University of Chicago has found that in pregnancy, while the T cell response to a fetus becomes tolerant to allow for successful pregnancy, the part of the immune system that produces antibodies (known as the humoral response) becomes sensitized, creating memory B cells that can later contribute to the rejection of a transplanted organ.

4 Jan 2021

Blood News and Research

Monitoring patients' hydroxychloroquine blood levels can predict their clotting risk

New mathematical model proposes optimal treatment strategies for COVID-19

Study: Decreased activation of LEF1 gene disrupts ordinary neuronal function

Scientist receives $1.37 million grant to advance metabolomics data

Mid-term clinical trial results of two cell therapies for critical limb ischemia show similar outcomes

Groundbreaking research project shows how brain health can traverse generations

Inhibition of blood clotting factor reduces the formation of brain metastases in mice

SARS-CoV-2 infected alveolar type-II lung cells show senescence

Heat treatment during chemotherapy is more effective at destroying cancer cells

Biological imbalance found to be the link between gum and kidney disease

Many health plans now must cover full cost of expensive HIV prevention drugs

Prolactin triggers male refractory period, indicates study

Routine eye imaging may provide clues to cognitive disorders in older people with type 1 diabetes

Research offers clues on why pregnancy may raise risk of organ transplant rejection

USF researchers discover promising new compound to open constricted airways

Sugar-binding protein could promote inflammation and worsen sepsis

New analysis finds no benefit in providing supplemental oxygen to mothers during childbirth

Inflammation marker linked to increased fatigue in prostate cancer patients treated with ADT

Six clearly distinguishable subtypes of prediabetes identified

People with detectable brown fat less likely to suffer cardiac and metabolic conditions

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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