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FDA grants Fast Track designation to Juventas' JVS-100 drug candidate and allows Phase 2b clinical trial

Juventas Therapeutics, Inc., a clinical-stage biotechnology company developing novel non-viral gene therapies that activate natural processes to repair the body, today announced that its product candidate, JVS-100, received Fast Track designation from the U.S. Food and Drug Administration for the treatment of advanced ischemic chronic heart failure.

16 Jun 2015

Pulmatrix completes previously announced merger and closes $10 million in private placement

Pulmatrix, Inc., previously known as Ruthigen, Inc., today announced the completion of its previously announced merger, effective June 15, 2015, and the closing of a private placement generating aggregate gross proceeds of $10.0 million. Participants in the private placement included pre-merger investors in Pulmatrix such as funds affiliated with 5AM Ventures, ARCH Venture Partners and Polaris Partners, as well as funds affiliated with Altitude Life Science Ventures.

16 Jun 2015

Pulmatrix signs ex-U.S. development agreement with Mylan for bronchodilator therapy

Pulmatrix, a clinical stage biopharmaceutical company developing innovative inhaled therapies for serious pulmonary diseases, today announced that it has entered into an ex-U.S. development agreement with Mylan N.V., one of the world's leading global pharmaceutical companies.

16 Jun 2015

New review outlines basic principles of dietary treatment

Thanks to screening of newborns and newly developed therapies, the population of patients with inherited metabolic disorders has expanded. As these patients age and enter adulthood, diet therapy will be the mainstay of treatment for their disorders.

16 Jun 2015

TUSM researchers reveal how scratching evokes pleasurable sensation in chronic itch patients

It's long been known that scratching evokes a rewarding and pleasurable sensation in patients with chronic itch. Now, researchers in the Department of Dermatology and Temple Itch Center at Temple University School of Medicine may be closer to understanding why.

16 Jun 2015

Researchers uncover new mechanism that innate immune system uses to curb viral infections

An innovative mechanism that the innate immune system uses to control viral infections has been uncovered by researchers at the University Medical Centers in Mainz and Freiburg. Central to this is the discovery that two different but related elements of the immune system can act together in concert to fight, for example, rotavirus infections.

16 Jun 2015

Men's poor health costs $36.9 billion a year for Canada

Canadian Men's Health Week is kicking off with an urgent message: Unhealthy lifestyle choices are running rampant, and they are costing this country an arm and a leg.

15 Jun 2015

Novartis announces FDA approval of Promacta for treatment of children with chronic ITP

Novartis announced today that the US Food and Drug Administration has approved Promacta (eltrombopag) for the treatment of children six years and older with chronic immune thrombocytopenia (ITP) who have had an insufficient response to corticosteroids, immunoglobulins or splenectomy. Promacta was approved by the FDA in 2008 for use in adult patients with the same condition.

15 Jun 2015

Vitamin D supplementation may treat Crohn’s disease

New research published in this month’s edition of United European Gastroenterology Journal suggests that supplementation with vitamin D may impact on the intestinal barrier dysfunction associated with Crohn’s disease, and could have a role in the treatment of the condition.

15 Jun 2015

Study examines mental health prognosis of young VTE patients

EuroHeartCare is the official annual meeting of the Council on Cardiovascular Nursing and Allied Professions of the European Society of Cardiology. The 2015 meeting is held 14 to 15 June in Dubrovnik, Croatia, in collaboration with the Croatian Association of Cardiology Nurses.

15 Jun 2015

Study shows that TNFi dose reduction strategy can help in optimal management of RA

The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) showed that, in rheumatoid arthritis (RA) patients, a good clinical response to maintenance treatment with a tumour necrosis factor inhibitor (TNFi) was maintained even when the dose was reduced by one-third.

15 Jun 2015

People with rheumatoid arthritis less likely to benefit from hepatitis B vaccine

The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) Press Conference showed that people with rheumatoid arthritis (RA) are less likely to be protected by hepatitis B vaccination than the general population.

14 Jun 2015

Vitamin D supplementation may affect intestinal barrier dysfunction associated with Crohn's disease

New research published in this month's edition of United European Gastroenterology journal suggests that supplementation with vitamin D may impact on the intestinal barrier dysfunction associated with Crohn's disease, and could have a role in the treatment of the condition.

13 Jun 2015

Lung cancer patients with comorbid conditions face higher risk of death

Lung cancer patients with comorbid conditions such as chronic obstructive pulmonary disease, diabetes, or congestive heart failure had a higher risk of death than lung cancer patients without comorbid conditions, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

12 Jun 2015

Study shows that ankylosing spondylitis can be predicted by low birth weight

The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) Press Conference showed that a diagnosis of ankylosing spondylitis (AS) can be predicted by low birth weight, having older siblings and hospitalisation for infection between the ages of 5-16 years.

12 Jun 2015

Tioga Pharmaceuticals announces commencement of asimadoline Phase 2 study for treatment of pruritus

Tioga Pharmaceuticals, a clinical stage biotechnology company, today announced the initiation of a Phase 2 clinical study of asimadoline, a novel, well-studied kappa-opioid receptor specific agonist, for the treatment of pruritus or itching. The double-blind, placebo-controlled clinical study is designed to evaluate the safety, tolerability, and clinical efficacy of asimadoline in patients with pruritus due to atopic dermatitis and is being conducted at 20 clinical study centers in the United States.

11 Jun 2015

AfBPM launches new educational tool to help assess, reduce medication abuse in home

The Alliance for Balanced Pain Management today launched a new educational tool – "Are You the Only One Taking Your Medicine?" – that consumers and health care providers can use to assess whether a home is at risk for medication misuse, abuse or diversion.

11 Jun 2015

New web-based community portal aims to improve diagnosis and treatment for sleep apnea

A new web-based community portal, http://www.MyApnea.Org, is recruiting patients, caregivers and those at risk for sleep apnea to join a growing community of patients and researchers to better understand sleep apnea through information sharing, support and research.

11 Jun 2015

Paediatric outpatient study compares effectiveness of three alternative treatments for type 1 diabetes

A Montréal research team, co-supervised by Dr. Rémi Rabasa-Lhoret from the IRCM and Dr. Laurent Legault from the Montreal Children's Hospital, undertook the first paediatric outpatient study to compare three alternative treatments for type 1 diabetes.

11 Jun 2015

Light exercise provides significant health benefits for older adults

An easy walk, slow dancing, leisurely sports such as table tennis, household chores and other light-intensity exercise may be nearly as effective as moderate or vigorous exercise for older adults - if they get enough of that type of activity.

11 Jun 2015

Chronic News and Research

FDA grants Fast Track designation to Juventas' JVS-100 drug candidate and allows Phase 2b clinical trial

Pulmatrix completes previously announced merger and closes $10 million in private placement

Pulmatrix signs ex-U.S. development agreement with Mylan for bronchodilator therapy

New review outlines basic principles of dietary treatment

TUSM researchers reveal how scratching evokes pleasurable sensation in chronic itch patients

Researchers uncover new mechanism that innate immune system uses to curb viral infections

Men's poor health costs $36.9 billion a year for Canada

Novartis announces FDA approval of Promacta for treatment of children with chronic ITP

Vitamin D supplementation may treat Crohn’s disease

Study examines mental health prognosis of young VTE patients

Study shows that TNFi dose reduction strategy can help in optimal management of RA

People with rheumatoid arthritis less likely to benefit from hepatitis B vaccine

Vitamin D supplementation may affect intestinal barrier dysfunction associated with Crohn's disease

Lung cancer patients with comorbid conditions face higher risk of death

Study shows that ankylosing spondylitis can be predicted by low birth weight

Tioga Pharmaceuticals announces commencement of asimadoline Phase 2 study for treatment of pruritus

AfBPM launches new educational tool to help assess, reduce medication abuse in home

New web-based community portal aims to improve diagnosis and treatment for sleep apnea

Paediatric outpatient study compares effectiveness of three alternative treatments for type 1 diabetes

Light exercise provides significant health benefits for older adults

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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