Genes News and Research

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Scientists discover new mechanism that regulates replication of insulin-producing beta cells in pancreas

Bringing scientists a step closer to new treatments for diabetes, researchers at the University of Pittsburgh School of Medicine and The Mount Sinai Medical Center have discovered a novel mechanism that regulates the replication of insulin-producing beta cells in the pancreas.

27 Mar 2013

Genetic variants influence childhood obesity, say researchers

Previous research has shown that obesity runs in families, and twin studies suggest that this is largely due to genetic factors, with heritability estimates over 50%.

27 Mar 2013

Novel molecular mechanism can prevent aging and cancer progression, say researchers

University of Montreal researchers have discovered a novel molecular mechanism that can potentially slows the aging process and may prevent the progression of some cancers.

27 Mar 2013

Study raises alarm over loss of individual 'genomic liberty' due to gene patents

Humans don't "own" their own genes, the cellular chemicsals that define who they are and what diseases they might be at risk for. Through more than 40,000 patents on DNA molecules, companies have essentially claimed the entire human genome for profit, report two researchers who analyzed the patents on human DNA. Their study, published March 25 in the journal Genome Medicine, raises an alarm about the loss of individual "genomic liberty."

27 Mar 2013

Academic medical centers launch ASD sub-registry within ResearchMatch

Each year, only five percent of the estimated 1.5 million children with an autism spectrum disorder in the US participate in clinical research studies. This is in stark contrast to pediatric cancer studies, which have a nearly 90 percent enrollment rate - a rate that has helped advance treatment and outcomes for childhood cancers substantially in the last decade.

27 Mar 2013

CHOP researchers moving closer to personalized medicine for children with cancer

Pediatric researchers, investigating the biology of brain tumors in children, are finding that crucial differences in how the same gene is mutated may call for different treatments.

27 Mar 2013

Molecular biologist hopes to learn why degenerative disorder affects specific brain cells

Dr. Santosh D'Mello, professor of molecular and cell biology at the University of Texas at Dallas, has received a federal grant for research that may shed light on why and how specific brain cells are affected by Huntington's disease, a devastating, degenerative brain disorder.

27 Mar 2013

Bladder cancer risk linked to genetic alterations

A new analysis has found that genetic alterations in a particular cellular pathway are linked with bladder cancer risk, recurrence, disease progression, and patient survival. Published early online in CANCER, a peer- reviewed journal of the American Cancer Society, the findings could help improve bladder cancer screening and treatment.

26 Mar 2013

Researchers re-programme other cells to become nerve cells, directly in the brain

The field of cell therapy, which aims to form new cells in the body in order to cure disease, has taken another important step in the development towards new treatments.

26 Mar 2013

New vaccine proves highly effective against H5N1 virus

Until now most experimental vaccines against the highly lethal H5N1 avian influenza virus have lacked effectiveness. But a new vaccine has proven highly effective against the virus when tested in both mice and ferrets. It is also effective against the H9 subtype of avian influenza.

26 Mar 2013

Study: Neural-crest stem cells also play a key role in building olfactory sensory neurons

When our noses pick up a scent, whether the aroma of a sweet rose or the sweat of a stranger at the gym, two types of sensory neurons are at work in sensing that odor or pheromone.

26 Mar 2013

UCI study finds novel molecular mechanism that helps trigger formation of long-term memory

UC Irvine neurobiologists have found a novel molecular mechanism that helps trigger the formation of long-term memory. The researchers believe the discovery of this mechanism adds another piece to the puzzle in the ongoing effort to uncover the mysteries of memory and, potentially, certain intellectual disabilities.

26 Mar 2013

First multi-gene DNA sequencing test launched for cancer patients

The first multi-gene DNA sequencing test that can help predict cancer patients' responses to treatment has been launched in the National Health Service, thanks to a partnership between scientists at the University of Oxford and Oxford University Hospitals NHS Trust.

26 Mar 2013

MIT biology professor named Pew's Biomedical Researcher of the Month

Biologist Mary Gehring, Ph.D. is The Pew Charitable Trusts' featured biomedical researcher of the month for her creative research on epigenetics in plants.

25 Mar 2013

Researchers study gene variants that bear signature for inflammatory disease susceptibility

In new research published in the April 4, 2013 issue of The American Journal of Human Genetics, researchers from Brigham and Women's Hospital demonstrate that some variants in our genes that could put a person at risk for inflammatory diseases such as multiple sclerosis, Crohn's disease or rheumatoid arthritis, have been the target of natural selection over the course of human history.

25 Mar 2013

Researchers expand hematopoietic stem cells for bone marrow transplantation

More than 50,000 stem cell transplants are performed each year worldwide. A research team led by Weill Cornell Medical College investigators may have solved a major issue of expanding adult hematopoietic stem cells (HSCs) outside the human body for clinical use in bone marrow transplantation -- a critical step towards producing a large supply of blood stem cells needed to restore a healthy blood system.

25 Mar 2013

Research may offer clues to why esophageal adenocarcinomas rates have increased rapidly

During the past 30 years, the number of patients with cancers that originate near the junction of the esophagus and stomach has increased approximately 600 percent in the United States. The first extensive probe of the DNA of these esophageal adenocarcinomas has revealed that many share a distinctive mix-up of letters of the genetic code, and found more than 20 mutated genes that had not previously been linked to the disease.

25 Mar 2013

Protein with key job in muscle function moonlights in nucleus to help regulate genes

A key building block of life, actin is one of the most abundant and highly conserved proteins in eukaryotic cells.

25 Mar 2013

Study uncovers new relationship between nuclear architecture, gene activity

Every time a cell divides it makes a carbon copy of crucial ingredients, including the histone proteins that are responsible for spooling yards of DNA into tight little coils.

25 Mar 2013

Study reveals role of SNX27 protein in brain function

What is it about the extra chromosome inherited in Down syndrome-chromosome 21-that alters brain and body development? Researchers at Sanford-Burnham Medical Research Institute have new evidence that points to a protein called sorting nexin 27, or SNX27.

25 Mar 2013

Genes News and Research

Scientists discover new mechanism that regulates replication of insulin-producing beta cells in pancreas

Genetic variants influence childhood obesity, say researchers

Novel molecular mechanism can prevent aging and cancer progression, say researchers

Study raises alarm over loss of individual 'genomic liberty' due to gene patents

Academic medical centers launch ASD sub-registry within ResearchMatch

CHOP researchers moving closer to personalized medicine for children with cancer

Molecular biologist hopes to learn why degenerative disorder affects specific brain cells

Bladder cancer risk linked to genetic alterations

Researchers re-programme other cells to become nerve cells, directly in the brain

New vaccine proves highly effective against H5N1 virus

Study: Neural-crest stem cells also play a key role in building olfactory sensory neurons

UCI study finds novel molecular mechanism that helps trigger formation of long-term memory

First multi-gene DNA sequencing test launched for cancer patients

MIT biology professor named Pew's Biomedical Researcher of the Month

Researchers study gene variants that bear signature for inflammatory disease susceptibility

Researchers expand hematopoietic stem cells for bone marrow transplantation

Research may offer clues to why esophageal adenocarcinomas rates have increased rapidly

Protein with key job in muscle function moonlights in nucleus to help regulate genes

Study uncovers new relationship between nuclear architecture, gene activity

Study reveals role of SNX27 protein in brain function

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