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New research finds how cancer cells acquire resistance to molecular-targeted drugs

Although molecular-targeted drugs have been known to show high efficacy to lung cancer patients, they also have limitations due to acquiring resistance to the drug used.

25 Feb 2019

Mayo Clinic researchers identify gene that may predict pancreatic cancer risk in diabetic patients

Mayo Clinic researchers have identified a gene called "UCP-1" that may predict the development of pancreatic cancer in people with Type 2 diabetes. Their findings are published in Gastroenterology.

25 Feb 2019

Researchers discover new and rare skeletal disease

Researchers at Karolinska Institutet in Sweden have discovered a new and rare skeletal disease. In a study published in the journal Nature Medicine they describe the molecular mechanism of the disease, in which small RNA molecules play a role that has never before been observed in a congenital human disease.

25 Feb 2019

Specific gene variation associated with ADHD could be tied to substance addiction

Some variations in the gene LPHN3 -associated with the attention deficit/hyperactivity disorder (ADHD) in kids and adults- could favor likelihood to smoke, consume alcohol, cannabis and other addictive substances, according to an article published in the journal Translational Psychiatry, from the Nature Publishing Group.

25 Feb 2019

Researchers discover origin of resistance to lung cancer

For treating cancer, drugs based on molecules known as tyrosine kinase inhibitors are sometimes used. One such tyrosine kinase inhibitor, called osimertinib, has been used to treat EGFR-mutated lung cancer with a certain degree of efficacy.

25 Feb 2019

Scientists identify cause of devastating pediatric brain disorder

An international effort led by physician-scientists at Rady Children's Institute for Genomic Medicine, in collaboration with a team at the Montreal Children's Hospital of the McGill University Health Centre, has identified the cause of a devastating pediatric brain disorder paving the way for the first step in developing potential therapies for this rare neurodegenerative condition.

25 Feb 2019

Researchers engineer 'antibody-like' T cell receptors to combat deadly virus

Researchers have engineered "antibody-like" T cell receptors that can specifically stick to cells infected with cytomegalovirus, or CMV, a virus that causes lifelong infection in more than half of all adults by age 40.

23 Feb 2019

Clinical study shows tolerability and safety of investigational drug in boys with DMD

Patients with Duchenne muscular dystrophy have few treatment options. Medications currently available or in development either target only a subset of DMD patients with a particular genetic mutation or cause significant side effects.

23 Feb 2019

Mechanism behind how diabetes causes muscle loss revealed

Diabetes mellitus is associated with various health problems including decline in skeletal muscle mass. A research group led by Professor Wataru Ogawa at the Kobe University Graduate School of Medicine revealed that elevation of blood sugar levels leads to muscle atrophy and that two proteins, WWP1 and KLF15, play key roles in this phenomenon.

23 Feb 2019

Study finds out similarity in function between healthy retina cell and tumor cell

How is a healthy retina cell like a tumor cell? It hijacks an energy-producing chemical reaction to churn out molecular building blocks. When tumor cells do it, they use the building blocks to make cancer grow and spread. But when retina cells do it, they renew photoreceptor membranes that keep our vision sharp.

22 Feb 2019

UVA scientist receives $1 million award to map out submicroscopic world

A scientist at the University of Virginia School of Medicine has received a prestigious three-year, $1 million award from the William M. Keck Foundation to develop a new and better way to map out the submicroscopic world.

22 Feb 2019

Akna protein plays a key role in the regulation of neural stem cells

The use of stem cells to repair organs is one of the foremost goals of modern regenerative medicine.

22 Feb 2019

Biologist uses new grant to find ways to eliminate schistosomiasis

A biologist at The University of Texas at Arlington is using a new grant to look for ways to finish off a disease that has stubbornly resisted all attempts to eradicate it.

22 Feb 2019

New study finds how high-fat diets fuel colorectal cancer growth

As cancer death rates drop overall, doctors have noted a frightening anomaly: deaths from colorectal cancer in people under 55 appear to be creeping up. According to the American Cancer Society, deaths in this younger group increased by 1 percent between 2007 and 2016.

22 Feb 2019

Researchers uncover interspecies communication between gut bacteria and host

Bacteria in the gut do far more than help digest food in the stomachs of their hosts, they can also tell the genes in their mammalian hosts what to do.

22 Feb 2019

New identified biomarker predicts patients who might benefit from HER2-targeted agents

In an effort to further individualize therapy and avoid over-treating patients, researchers at the Johns Hopkins Kimmel Cancer Center report a new study using PET scans has identified a biomarker that may accurately predict which patients with one type of HER2-positive breast cancer might best benefit from standalone HER2-targeted agents, without the need for standard chemotherapy.

22 Feb 2019

Protein C News and Research

New research finds how cancer cells acquire resistance to molecular-targeted drugs

Mayo Clinic researchers identify gene that may predict pancreatic cancer risk in diabetic patients

Researchers discover new and rare skeletal disease

Specific gene variation associated with ADHD could be tied to substance addiction

Researchers discover origin of resistance to lung cancer

Scientists identify cause of devastating pediatric brain disorder

Researchers engineer 'antibody-like' T cell receptors to combat deadly virus

Clinical study shows tolerability and safety of investigational drug in boys with DMD

Mechanism behind how diabetes causes muscle loss revealed

Study finds out similarity in function between healthy retina cell and tumor cell

UVA scientist receives $1 million award to map out submicroscopic world

Akna protein plays a key role in the regulation of neural stem cells

Biologist uses new grant to find ways to eliminate schistosomiasis

New study finds how high-fat diets fuel colorectal cancer growth

Researchers uncover interspecies communication between gut bacteria and host

New identified biomarker predicts patients who might benefit from HER2-targeted agents

Study offers new insights into mechanisms of changes in erythrocytes under stress

Mitochondrial proteotoxicity appears to be epicentre of molecular pathogenesis

Newly designed molecule could benefit people with Friedrich's Ataxia

Phase 1 data reinforce safety profile of new drug for treating Duchenne muscular dystrophy

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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