Genes News and Research

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MiR-198 controls migration of skin cells necessary for wounds to close and heal

Patients with diseases such as diabetes suffer from painful wounds that take a long time to heal making them more susceptible to infections that could even lead to amputations. A*STAR's discovery paves the way for therapeutics to improve healing of such chronic wounds, which are a significant burden to patients.

11 Mar 2013

Influenza drug: an interview with Dr Jenny McKimm-Breschkin, CSIRO

Influenza or flu for short is caused by a family of viruses, which can be called influenza A or influenza B. Influenza A viruses are found in humans, animals – like swine and horses- and mostly aquatic birds. Influenza B is only found in humans.

11 Mar 2013

UT Southwestern researcher to receive March of Dimes Prize in Developmental Biology

Dr. Eric Olson, chairman of molecular biology at UT Southwestern Medical Center, is the 2013 recipient of the March of Dimes Prize in Developmental Biology for identifying key genetic pathways in the formation of the heart and other muscles.

11 Mar 2013

Combining mitochondrial inhibitors could improve efficacy of BRAF inhibitors in melanoma

A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism.

11 Mar 2013

Viruses and genes may increase risk of schizophrenia

Viruses and genes interact in a way that may increase the risk of developing schizophrenia significantly. This happens already in the developing foetus.

11 Mar 2013

Planar cell polarity genes control connectivity of enteric neurons

The enteric nervous system (ENS), the "little brain" that resides within the gut wall, governs motility, secretion, and blood flow in the human gastrointestinal tract. Failure of the ENS to develop normally leads to congenital megacolon (Hirschsprung Disease) while loss of normal gut innervation is thought to contribute to debilitating motility disorders, such as irritable bowel syndrome.

11 Mar 2013

New technology can turn off genes more precisely, say UCSF researchers

Scientists at UC San Francisco have found a more precise way to turn off genes, a finding that will speed research discoveries and biotech advances and may eventually prove useful in reprogramming cells to regenerate organs and tissues.

8 Mar 2013

Researchers discover ovarian stem-like epithelial cells that can mutate to form tumors

In collaboration with colleagues at Cornell University, a team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has discovered cells with stem-cell properties in the ovary that can mutate to form tumors.

8 Mar 2013

Study helps explain why viruses often spread through the brain in patchwork patterns

Viruses often spread through the brain in patchwork patterns, infecting some cells but missing others. New research at Washington University School of Medicine in St. Louis helps explain why. The scientists showed that natural immune defenses that resist viral infection are turned on in some brain cells but switched off in others.

8 Mar 2013

UNMC provides important genetic tool for scientists to better utilize library of mutant staph bacteria

Through the creation of a library of more than 2,000 mutant strains of the Staphylococcus aureus bacteria, the University of Nebraska Medical Center has provided an important tool for scientists around the world seeking answers for how to better deal with staph infections.

8 Mar 2013

Researchers explore genetic testing to identify people at high risk for preventable disease

In ten years time, routine preventive health care for adults may include genetic testing alongside the now familiar tests for cholesterol levels, mammography and colonoscopy.

8 Mar 2013

Salty diet may trigger autoimmune disease

Results from two studies published in Nature show that eating a salty diet may trigger the development of autoimmunity.

7 Mar 2013

Salk epigenetic findings may aid in crop production and study of human diseases

Scientists at the Salk Institute for Biological Studies have identified patterns of epigenomic diversity that not only allow plants to adapt to various environments, but could also benefit crop production and the study of human diseases.

7 Mar 2013

Genomic analysis could illuminate more options in developing precise treatments for cancer

Investigators working on the precision medicine initiative at The Cancer Institute of New Jersey are embarking on a genomic analysis study which could illuminate more options in developing personalized and precise treatments for cancer patients.

7 Mar 2013

UCLA scientists discover new genetic risk factor for Alzheimer's disease

Scientists at UCLA have discovered a new genetic risk factor for Alzheimer's disease by screening people's DNA and then using an advanced type of scan to visualize their brains' connections.

7 Mar 2013

Study now tells physicians that dystonia can occur in African-American patients

A pair of studies tells the tale of how a neuroscientist at Mayo Clinic in Florida helped to discover the first African-American family to have inherited the rare movement disorder dystonia, which causes repetitive muscle contractions and twisting, resulting in abnormal posture.

7 Mar 2013

‘New Frontiers in Neurodegenerative Disease Research’ symposium to be held from Feb. 4-7

At the Keystone Symposium "New Frontiers in Neurodegenerative Disease Research," held 4-7 February in Santa Fe, New Mexico, researchers explored the processes that lead to a variety of diseases, including Alzheimer's and Lou Gehrig's disease (amyotrophic lateral sclerosis, ALS).

7 Mar 2013

MicroRNA expression signatures may help define progression of Barrett's esophagus

A series of microRNA expression signatures that may help to define progression of the precancerous condition Barrett's esophagus into esophageal adenocarcinoma was reported recently in Cancer Prevention Research, a journal of the American Association for Cancer Research.

7 Mar 2013

Vitamin B12 and folate alleviate negative symptoms in patients with schizophrenia

Adding the dietary supplements folate and vitamin B12 to treatment with antipsychotic medication improved a core symptom component of schizophrenia in a study of more than 100 patients.

7 Mar 2013

Insight into how Th17 cell growth influences development of immune responses

New work from the Broad Institute's Klarman Cell Observatory, Brigham and Women's Hospital, Harvard University, MIT, and Yale University expands the understanding of how one type of immune cell - known as a T helper 17 or Th17 cell - develops, and how its growth influences the development of immune responses.

7 Mar 2013

Genes News and Research

MiR-198 controls migration of skin cells necessary for wounds to close and heal

Influenza drug: an interview with Dr Jenny McKimm-Breschkin, CSIRO

UT Southwestern researcher to receive March of Dimes Prize in Developmental Biology

Combining mitochondrial inhibitors could improve efficacy of BRAF inhibitors in melanoma

Viruses and genes may increase risk of schizophrenia

Planar cell polarity genes control connectivity of enteric neurons

New technology can turn off genes more precisely, say UCSF researchers

Researchers discover ovarian stem-like epithelial cells that can mutate to form tumors

Study helps explain why viruses often spread through the brain in patchwork patterns

UNMC provides important genetic tool for scientists to better utilize library of mutant staph bacteria

Researchers explore genetic testing to identify people at high risk for preventable disease

Salty diet may trigger autoimmune disease

Salk epigenetic findings may aid in crop production and study of human diseases

Genomic analysis could illuminate more options in developing precise treatments for cancer

UCLA scientists discover new genetic risk factor for Alzheimer's disease

Study now tells physicians that dystonia can occur in African-American patients

‘New Frontiers in Neurodegenerative Disease Research’ symposium to be held from Feb. 4-7

MicroRNA expression signatures may help define progression of Barrett's esophagus

Vitamin B12 and folate alleviate negative symptoms in patients with schizophrenia

Insight into how Th17 cell growth influences development of immune responses

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