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Lab profiles differentiate MIS-C from severe COVID-19 in children

In the early days of the COVID-19 pandemic, the SARS-CoV-2 virus seemed only rarely to have serious complications in children.

30 Jul 2020

Clinical study evaluates potential of oral cancer drug to reduce respiratory symptoms of COVID-19

Researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute and The Ohio State University Wexner Medical Center are conducting a new clinical trial to determine if an oral cancer drug called ibrutinib can also help patients with cancer or other immunocompromised conditions recover from COVID-19.

29 Jul 2020

Avacta and Daewoong Pharmaceutical expand partnership to include COVID-19 neutralising Affimer therapy

Avacta Group plc, is pleased to announce an expansion of its collaboration and license agreement with Daewoong Pharmaceutical Co.Ltd and AffyXell Therapeutics.

29 Jul 2020

Identification of MTK1 SAPKKK as new human oxidative stress sensor

In an aging society, various studies are being conducted to explore the relationship between active oxygen and aging-related diseases such as cancer, chronic inflammatory diseases, and metabolic syndrome.

28 Jul 2020

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

Analyses of lung fluid cells from COVID-19 patients conducted on the nation's fastest supercomputer point to gene expression patterns that may explain the runaway symptoms produced by the body's response to SARS-CoV-2.

28 Jul 2020

FDA approves first CAR T-cell therapy for patients with mantle cell lymphoma

The U.S. Food and Drug Administration granted accelerated approval for brexucabtagene autoleucel (TECARTUS™, formerly KTE-X19) as the first and only CAR T-cell therapy for patients with mantle cell lymphoma (MCL) relapsed or refractory to prior treatments.

28 Jul 2020

Varying immune system responses can predict severe COVID-19 outcomes

The differing immune system responses of patients with COVID-19 can help predict who will experience moderate and severe consequences of disease, according to a new study by Yale researchers published July 27 in the journal Nature.

27 Jul 2020

Study reveals manifold applications of cytokine transcriptional response modules in COVID-19

In a recent bioRxiv* study, UK researchers used interleukin modules to investigate the pathology of coronavirus disease (COVID-19).

27 Jul 2020

Higher levels of TGFBIp are correlated with severity of COVID-19 symptoms

A new study found raised levels of transforming growth factor beta-induced protein (TGFBIp) in blood sampled from roughly 100 people hospitalized for COVID-19, and further found that elevated levels of both the normal and acetylated forms of TGFBIp correlated with the severity of disease symptoms in these patients.

25 Jul 2020

Combining two immunotherapies into a single treatment found to be more effective

Some of the most promising advances in cancer treatment have centered on immunotherapies that rev up a patient's immune system to attack cancer. But immunotherapies don't work in all patients, and researchers have been searching for ways to increase their effectiveness.

23 Jul 2020

Study uncovers dual role for molecule involved in autoimmune eye disease

The inflammatory molecule interleukin-17A (IL-17A) triggers immune cells that in turn reduce IL-17A's pro-inflammatory activity, according to a study by National Eye Institute researchers.

23 Jul 2020

Mysterious enzyme inhibits inflammation in blood vessels, LJI study shows

Scrape your knee, and you'll see some red puffiness appear around the injury. This is inflammation, and it is driven by the immune system.

23 Jul 2020

Vitamin D could help suppress excessive T cell-mediated lung inflammation in severe COVID-19

As COVID-19 continues to spread over the world scientists continue to seek the reasons for the difference in disease severity from person to person.

22 Jul 2020

Autopsies reveal unexpected changes in the hearts of COVID-19 patients

A series of autopsies conducted by LSU Health New Orleans pathologists shows the damage to the hearts of COVID-19 patients is not the expected typical inflammation of the heart muscle associated with myocarditis, but rather a unique pattern of cell death in scattered individual heart muscle cells.

21 Jul 2020

Mouse model of fatal COVID-19 developed for vaccine and drug testing

Now, a new study published on the preprint server bioRxiv in July 2020 presents an engineered transgenic mouse that reproduces the functional and clinical characteristics of severe human SARS-CoV-2 infection.

21 Jul 2020

Pfizer/BioNTech COVID-19 vaccine elicits both neutralizing antibodies and T cell response

A new study published on the preprint server medRxiv by a research group from the U.S. and Germany indicates that a novel BNT162b1 RNA-based vaccine against coronavirus disease (COVID-19) induces functional and proinflammatory T cell responses in almost all participants – marking another landmark achievement for this promising vaccine candidate.

21 Jul 2020

Experimental treatment protocol can reduce COVID-related hospital mortality by 65%

Findings of a new study show that a widely available immunosuppressant used for treatment of rheumatic musculoskeletal diseases (RMDs) accelerates respiratory recovery, lowers hospital-mortality and reduces the likelihood of invasive mechanical ventilation compared to supportive care only.

21 Jul 2020

Cytokine News and Research

Lab profiles differentiate MIS-C from severe COVID-19 in children

Clinical study evaluates potential of oral cancer drug to reduce respiratory symptoms of COVID-19

Avacta and Daewoong Pharmaceutical expand partnership to include COVID-19 neutralising Affimer therapy

Identification of MTK1 SAPKKK as new human oxidative stress sensor

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

FDA approves first CAR T-cell therapy for patients with mantle cell lymphoma

Varying immune system responses can predict severe COVID-19 outcomes

Study reveals manifold applications of cytokine transcriptional response modules in COVID-19

Higher levels of TGFBIp are correlated with severity of COVID-19 symptoms

Combining two immunotherapies into a single treatment found to be more effective

Study uncovers dual role for molecule involved in autoimmune eye disease

Mysterious enzyme inhibits inflammation in blood vessels, LJI study shows

Vitamin D could help suppress excessive T cell-mediated lung inflammation in severe COVID-19

Autopsies reveal unexpected changes in the hearts of COVID-19 patients

Mouse model of fatal COVID-19 developed for vaccine and drug testing

Pfizer/BioNTech COVID-19 vaccine elicits both neutralizing antibodies and T cell response

Experimental treatment protocol can reduce COVID-related hospital mortality by 65%

Antibody profile and estimated seroprevalence in COVID-19 infection

A multi-omics single cell analysis on COVID-19

Type 1 interferon deficiency as a biomarker for detecting patients at risk of severe COVID-19

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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