Genetic Engineering News and Research

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New RNA tools for CRISPR/Cas9

Integrated DNA Technologies (IDT) will host an informative webinar, entitled ‘New RNA Tools for Optimized CRISPR/Cas9 Genome Editing’, on Wednesday, October 7, 2015. Ashley Jacobi, a scientist in the Molecular Genetics Applied Research Group at IDT, and an expert in the application of synthetic nucleic acids, will present the webinar at 9 am and 1 pm Central Standard Time.

From Integrated DNA Technologies 1 Oct 2015

New review article discusses benefits, limitations of current screening mammography practices

While screening mammography has a well-established history of reducing death from breast cancer and enabling earlier detection of breast disease, questions regarding overtreatment and overdiagnosis have entered the screening debate.

30 Sep 2015

Glowing protein may replace fiber optic cable as light source in optogenetics research

Optogenetics has taken neuroscience by storm in recent years because the technique allows scientists to study the brain conveniently in animals, activating or inhibiting selected groups of neurons at the flip of a switch. Most often, scientists use a fiber optic cable to deliver light into the brain.

30 Sep 2015

Academies and DFG point out limitations and risks of new genome editing techniques

More efficient bacteria and yeasts for use in fuel and drug production, new strategies to combat antibiotic-resistant germs, and innovative plant breeding methods - new molecular biology techniques that permit targeted genetic modification are giving rise to many promising new opportunities in research and application.

29 Sep 2015

Scientists identify different CRISPR system with potential to advance genetic engineering

A team including the scientist who first harnessed the revolutionary CRISPR-Cas9 system for mammalian genome editing has now identified a different CRISPR system with the potential for even simpler and more precise genome engineering.

26 Sep 2015

UCSF researchers develop molecular 'on switch' that allows control over the actions of T cells

UC San Francisco researchers have engineered a molecular "on switch" that allows tight control over the actions of T cells, immune system cells that have shown great potential as therapies for cancer. The innovation lays the groundwork for sharply reducing severe, sometimes deadly side effects that have been a significant hurdle to advancing T cell-based treatments.

25 Sep 2015

MIT researchers devise new system to genetically engineer viruses to combat harmful bacteria

In the hunt for new ways to kill harmful bacteria, scientists have turned to a natural predator: viruses that infect bacteria. By tweaking the genomes of these viruses, known as bacteriophages, researchers hope to customize them to target any type of pathogenic bacteria.

23 Sep 2015

TSRI study reveals key morphine regulator that may help develop less-addictive pain medications

Once used in the 18th century as currency to reverse the trade imbalance between China and Britain, opiates that contain morphine have been misunderstood almost continually ever since.

23 Sep 2015

Researchers receive $13 million NIH grant to develop new stem cell-based assays for studying autism

The National Institutes of Health has awarded a $13 million grant over five years to develop and disseminate new stem cell-based technologies and assays for studying autism spectrum disorder (ASD) and other mental health diseases to a consortium of researchers at the University of California, San Diego and the Salk Institute for Biological Studies, working in tandem with leaders in the biotechnology sector.

23 Sep 2015

Genetically engineered vaccine eradicates precancerous cervical lesions

Scientists have used a genetically engineered vaccine to successfully eradicate high-grade precancerous cervical lesions in nearly one-half of women who received the vaccine in a clinical trial. The goal, say the scientists, was to find nonsurgical ways to treat precancerous lesions caused by HPV.

18 Sep 2015

Precise mouse brain map may provide new insights into brain circuits and origins of mental illnesses

Scientists at Duke University have released a highly detailed model of connections in the mouse brain that could provide generations of neuroscientists new insights into brain circuits and origins of mental illness, such as depression and schizophrenia.

16 Sep 2015

UCSF receives $5 million grant to create online database on all types of cancer

UC San Francisco has received a National Cancer Institute grant of $5 million over the next five years to lead a massive effort to integrate the data from all experimental models across all types of cancer.

16 Sep 2015

UNC scientists create smarter immune cells to treat Parkinson's disease

As a potential treatment for Parkinson's disease, scientists at the University of North Carolina at Chapel Hill have created smarter immune cells that produce and deliver a healing protein to the brain while also teaching neurons to begin making the protein for themselves.

14 Sep 2015

Surgeons participate in record-setting day of organ transplantation at Baylor University Medical Center

One week ago, surgical teams took part in a record-setting day of organ transplantation at Baylor University Medical Center at Dallas. Surgeons on the medical staff performed nine organ transplants on seven patients in one calendar day.

11 Sep 2015

Penn Medicine researchers show that DNA editing errors can lead to cancer

Sometimes when the immune system makes small mistakes, the body amplifies its response in a big way: Editing errors in the DNA of developing T and B cells can cause blood cancers. Now, researchers from the Perelman School of Medicine, University of Pennsylvania have shown that when the enzyme key to cutting and pasting segments of DNA hits so-called "off-target" spots on a chromosome, the development of immune cells can lead to cancer in animal models.

11 Sep 2015

Research: Cancer preventative surgery may not be necessary in the future

Surgery to remove the breasts of women at increased risk of developing breast cancer may not be necessary in the future, according to research published in EBioMedicine. Two new studies looking at the effect the menstrual cycle has on the development of breast and ovarian cancer reveal alternative prevention strategies that may render surgery unnecessary.

11 Sep 2015

A new approach to prevent breast and ovarian cancer

Surgery to remove the breasts of women at increased risk of developing breast cancer may not be necessary in the future, according to research published in EBioMedicine.

10 Sep 2015

Scientists identify new drug target to treat heart arrhythmias

Scientists at The Ohio State University Davis Heart and Lung Research Institute have identified a new target they hope will help make the next drug discovery for patients suffering from heart arrhythmias happen sooner.

9 Sep 2015

Penns' Abramson Cancer Center rated as 'exceptional' by NCI

The University of Pennsylvania's Abramson Cancer Center (ACC) has received an "exceptional" rating by the National Cancer Institute during an extensive peer-review process for its five-year competitive research support grant. The rating is the highest possible for an NCI cancer center.

9 Sep 2015

UCSF researchers lead $10 million research project on pediatric cancer

Researchers at UC San Francisco are leading a five-year, $10 million research project dedicated to pediatric cancer, funded by the first grant of its kind to focus on a molecular pathway that underlies many cancers rather than on a cancer in a particular organ or tissue in the body.

9 Sep 2015

Genetic Engineering News and Research

New RNA tools for CRISPR/Cas9

New review article discusses benefits, limitations of current screening mammography practices

Glowing protein may replace fiber optic cable as light source in optogenetics research

Academies and DFG point out limitations and risks of new genome editing techniques

Scientists identify different CRISPR system with potential to advance genetic engineering

UCSF researchers develop molecular 'on switch' that allows control over the actions of T cells

MIT researchers devise new system to genetically engineer viruses to combat harmful bacteria

TSRI study reveals key morphine regulator that may help develop less-addictive pain medications

Researchers receive $13 million NIH grant to develop new stem cell-based assays for studying autism

Genetically engineered vaccine eradicates precancerous cervical lesions

Precise mouse brain map may provide new insights into brain circuits and origins of mental illnesses

UCSF receives $5 million grant to create online database on all types of cancer

UNC scientists create smarter immune cells to treat Parkinson's disease

Surgeons participate in record-setting day of organ transplantation at Baylor University Medical Center

Penn Medicine researchers show that DNA editing errors can lead to cancer

Research: Cancer preventative surgery may not be necessary in the future

A new approach to prevent breast and ovarian cancer

Scientists identify new drug target to treat heart arrhythmias

Penns' Abramson Cancer Center rated as 'exceptional' by NCI

UCSF researchers lead $10 million research project on pediatric cancer

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