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Immunomolecular detection method to rapidly and accurately detect complete SARS-CoV-2 virions

Researchers developed a hybrid assay incorporating immunological antibody-based viral spike protein capture with molecular nucleic acid amplification by qRT-PCR.

24 Feb 2022

Study reveals sex-dimorphic immune imprints and in vivo functional impacts of mild COVID-19

Researchers used a systems immunology approach to analyze the immune states of healthy and non-obese subjects who recovered from mild COVID-19 and compared them with age- and sex-matched COVID-19-naive controls.

24 Feb 2022

Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

In a new study, researchers studied SARS-CoV-2 infection on the transcription of mitochondrial oxidative phosphorylation, glycolysis, nutrient sensing, and stress response genes.

24 Feb 2022

Researchers create artificial tendons in vitro from human stem cells

Researchers from Tokyo Medical and Dental develop artificial tendons in vitro from human stem cells that could fix common tendon injuries such as Achilles tendon rupture.

23 Feb 2022

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

The role played by the host enzyme TMPRSS2 in infection and cancer is the focus of a new study.

23 Feb 2022

Study explores the decline in viral load and immune response in COVID-19 patients

Researchers described the changes in viral ribonucleic acid the decline in viral load, and the immune response of SARS-CoV-2-infected patients, in a new preprint study.

22 Feb 2022

An abundance of SARS-CoV-2-like viruses in hunted wild animals traded in China

New research published in the journal Cell assesses the viromes of 18 different species of game animals across China to predict potential pathogens similar to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could infect human populations.

22 Feb 2022

Research shows the impact of accessory genes deletion in SARS-CoV-2 evolution

In a recent study published in the journal PLoS ONE, researchers investigated the effect of genetic variability based on accessory gene deletions on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and the clinical severity of coronavirus disease 2019 (COVID-19).

22 Feb 2022

The logic that controls gene regulation in human cells discovered

A research group at the University of Helsinki has discovered the logic that controls gene regulation in human cells. In the future, this new knowledge can be applied to, for example, investigating cancers and other genetic diseases.

21 Feb 2022

Full schedule of CoronaVac vaccine shown to be highly effective in children

A recent study on vaccine effectiveness showed that a complete primary immunization with CoronaVac effectively protects against severe coronavirus disease 2019 (COVID-19) for children and adolescents between 6 and 16 years of age – consistent with the results from phase 2 clinical trials. The paper is currently available on the Preprints with The Lancet* server while it undergoes peer review.

20 Feb 2022

Four times as many children hospitalized during Omicron COVID wave compared to Delta

The emergence of the SARS-CoV-2 Delta and Omicron variants caused severe disease and hospitalizations among children and adolescents.

20 Feb 2022

Codiak's publication highlights the ability of exoASO-STAT6 to selectively target tumor-associated macrophages

Codiak BioSciences, Inc., a clinical-stage biopharmaceutical company pioneering the development of exosome-based therapeutics as a new class of medicines, today announced the online publication of a new manuscript, Exosome mediated genetic reprogramming of tumor associated macrophages by exoASO-STAT6 leads to potent monotherapy anti-tumor efficacy, in the American Association for the Advancement of Science's journal, Science Advances.

18 Feb 2022

Novel approach pinpoints genetic variants involved in congenital heart disease

Nearly 1 percent of all children are born with congenital heart disease - a range of potentially life-threatening problems with the structure and function of their hearts. For most children, the precise causes of these frightening defects are unknown.

18 Feb 2022

Transcription News and Research

Immunomolecular detection method to rapidly and accurately detect complete SARS-CoV-2 virions

Study reveals sex-dimorphic immune imprints and in vivo functional impacts of mild COVID-19

Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

Researchers create artificial tendons in vitro from human stem cells

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

Study explores the decline in viral load and immune response in COVID-19 patients

An abundance of SARS-CoV-2-like viruses in hunted wild animals traded in China

Research shows the impact of accessory genes deletion in SARS-CoV-2 evolution

The logic that controls gene regulation in human cells discovered

Full schedule of CoronaVac vaccine shown to be highly effective in children

Four times as many children hospitalized during Omicron COVID wave compared to Delta

Codiak's publication highlights the ability of exoASO-STAT6 to selectively target tumor-associated macrophages

Novel approach pinpoints genetic variants involved in congenital heart disease

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Study explores the high viral loads of SARS-CoV-2 Delta and Alpha variants

Characterization of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military

Detection of SARS-CoV-2 RNA by plasmonic-magnetic nanorobots

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

CRISPR-Cas12a assay to diagnose SARS-CoV-2 infection and detect strain-specific SNPs for variant identification

Prediction of SARS-CoV-2 epitope candidates for future vaccines

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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