Genes News and Research

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Salt can induce and worsen pathogenic immune system responses in mice

For the past few decades, health officials have been reporting increases in the incidence of autoimmune diseases such as multiple sclerosis (MS). Now researchers at Yale School of Medicine, Harvard Medical School and the Broad Institute have identified a prime suspect in the mystery - dietary salt.

7 Mar 2013

Researchers discover likely origin of epithelial ovarian cancer

Cornell University researchers have discovered a likely origin of epithelial ovarian cancer (ovarian carcinoma), the fifth leading cause of cancer death among women in the United States.

7 Mar 2013

Fractional anisotropy examines age-related decline in cerebral white matter in schizophrenia, MDD

Many lines of evidence indicate that schizophrenia is a disorder of neurodevelopment. For example, genes implicated in the heritable risk for schizophrenia are also implicated in the development of nerve cells and their connections.

7 Mar 2013

Study combines induced pluripotent stem cell technology and genetic correction to treat DMD

Researchers at the University of Minnesota's Lillehei Heart Institute have combined genetic repair with cellular reprogramming to generate stem cells capable of muscle regeneration in a mouse model for Duchenne Muscular Dystrophy (DMD).

7 Mar 2013

Selective activation of the dentate gyrus can reduce anxiety without affecting learning

Columbia University Medical Center (CUMC) researchers have found the first evidence that selective activation of the dentate gyrus, a portion of the hippocampus, can reduce anxiety without affecting learning.

7 Mar 2013

Chemotherapy-free stem cell transplant shows promise for sickle cell disease

Two brothers have been cured of their sickle cell disease at the University of Illinois Hospital & Health Sciences System using a relatively uncommon type of stem cell transplant that is performed without chemotherapy.

6 Mar 2013

Screening healthy adults could potentially prevent rare genetic disorders

Millions of people unknowingly carry rare gene mutations that put them at high risk of developing preventable diseases such as colorectal cancer, breast cancer, and several catastrophic blood vessel disorders.

6 Mar 2013

Scientists discover key biochemical step underlying heart failure

Some 5.8 million Americans suffer from heart failure, a currently incurable disease. But scientists at Temple University School of Medicine's (TUSM) Center for Translational Medicine have discovered a key biochemical step underlying the condition that could aid the development of new drugs to treat and possibly prevent it.

6 Mar 2013

University of Manchester leads systems medicine research network for inflammatory bowel disease

The University of Manchester is leading a €12 million systems medicine research network to identify better treatments for Inflammatory Bowel Disease like Crohn's Disease.

6 Mar 2013

Viewpoints: Disappointing 'surprises' in health law; Cuts in graduate medical training threatens physician supply; Va. can afford Medicaid expansion

The proposed 2.3 percent reduction in (Medicare Advantage plan) payments, which comes on top of cuts already scheduled under the Affordable Care Act, pays no mind to the potential impact on quality of care throughout the program. These cuts will apply to all plans no matter the value they bring in providing quality care to beneficiaries or offering innovative solutions that could ultimately be scaled and applied to the broader program.

5 Mar 2013

Gene cluster implicated in Behçet's disease

Scientists may have uncovered an underlying genetic susceptibility for Behçet's disease in East Asian patients.

5 Mar 2013

Schizophrenic people with MIR137 tend to develop illness at younger age

Some of the dramatic differences seen among patients with schizophrenia may be explained by a single gene that regulates a group of other schizophrenia risk genes. These findings appear in a new imaging-genetics study from the Centre for Addiction and Mental Health (CAMH).

5 Mar 2013

KMO gene variant associated with increased production of kynurenic acid

Researchers at Karolinska Institutet in Sweden have found an explanation for why the level of kynurenic acid (KYNA) is higher in the brains of people with schizophrenia or bipolar disease with psychosis. The study, which is published in the scientific periodical Molecular Psychiatry, identifies a gene variant associated with an increased production of KYNA.

5 Mar 2013

Five scientists aim to make strides in predicting and preventing preterm birth

Five researchers from four states are investigating how genetics and infections interact to cause preterm birth as well as how proteins and hormones regulate a healthy pregnancy, all with the goal of giving more babies a healthy start in life, the March of Dimes announced today.

5 Mar 2013

HIV might promote aging and disease progression in people with HCV, study results suggest

Infectious disease experts at Johns Hopkins have found that among people infected with the hepatitis C virus, co-infection with HIV, speeds damage and scarring of liver tissue by almost a decade.

5 Mar 2013

AAP, ACMG release guidelines on best practices for genetic testing and screening of children

For the first time, the American Academy of Pediatrics (AAP) and the American College of Medical Genetics and Genomics (ACMG) spoke with one voice and released a set of recommendations and guidelines on best practices for genetic testing and screening of children.

5 Mar 2013

Eating your greens may be even more important than previously thought

Eating your greens may be even more important than previously thought, with the discovery that an immune cell population essential for intestinal health could be controlled by leafy greens in your diet.

5 Mar 2013

Idera announces new data from IMO-3100 and IMO-8400 preclinical study on psoriasis

Idera Pharmaceuticals, Inc. today announced the presentation of new data showing that its selective Toll-like receptor antagonists, IMO-3100 and IMO-8400, normalized the gene expression of important cytokines in a preclinical study of skin inflammation that is commonly used as a model of psoriasis.

4 Mar 2013

Horizon forms 3 new Centers of Excellence for gene editing in Asia

Horizon Discovery (Horizon), a leading provider of research tools to support the development of personalized medicines, today announced it has established three new Centers of Excellence (CoE's) for gene editing in Asia.

4 Mar 2013

Researchers discover new candidate disease proteins for neurodegenerative disorders

A multi-institution group of researchers has found new candidate disease proteins for neurodegenerative disorders.

4 Mar 2013

Genes News and Research

Salt can induce and worsen pathogenic immune system responses in mice

Researchers discover likely origin of epithelial ovarian cancer

Fractional anisotropy examines age-related decline in cerebral white matter in schizophrenia, MDD

Study combines induced pluripotent stem cell technology and genetic correction to treat DMD

Selective activation of the dentate gyrus can reduce anxiety without affecting learning

Chemotherapy-free stem cell transplant shows promise for sickle cell disease

Screening healthy adults could potentially prevent rare genetic disorders

Scientists discover key biochemical step underlying heart failure

University of Manchester leads systems medicine research network for inflammatory bowel disease

Viewpoints: Disappointing 'surprises' in health law; Cuts in graduate medical training threatens physician supply; Va. can afford Medicaid expansion

Gene cluster implicated in Behçet's disease

Schizophrenic people with MIR137 tend to develop illness at younger age

KMO gene variant associated with increased production of kynurenic acid

Five scientists aim to make strides in predicting and preventing preterm birth

HIV might promote aging and disease progression in people with HCV, study results suggest

AAP, ACMG release guidelines on best practices for genetic testing and screening of children

Eating your greens may be even more important than previously thought

Idera announces new data from IMO-3100 and IMO-8400 preclinical study on psoriasis

Horizon forms 3 new Centers of Excellence for gene editing in Asia

Researchers discover new candidate disease proteins for neurodegenerative disorders

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