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Vilcek Foundation prizes awarded to immigrants for their work on human biology and disease

The Vilcek Foundation is pleased to announce the winners of the 2019 Vilcek Foundation Prizes for Biomedical Science, awarded to immigrants who have made significant contributions to the field. Dr. Angelika Amon will receive the $100,000 Vilcek Prize, while Drs. Amit Choudhary, Jeanne T. Paz, and Mikhail G. Shapiro will each receive the $50,000 Vilcek Prize for Creative Promise.

8 Feb 2019

Compounds found in fish oil may prevent pregnancy complications, finds study

Compounds found in fish oil prevent pregnancy complications, including preterm birth, neonatal death, and stillbirth, in mice when the complications are caused by a common oral bacteria, according to research published today in the journal JCI Insight.

8 Feb 2019

Immunity to dengue can protect against Zika infection, study shows

In the epicenter of the Zika epidemic in northeast Brazil, 73 percent of people living in an urban slum in Salvador were infected in 2015. However, in this highly affected population, those with immunity to dengue, a genetically similar virus, had a reduced risk of infection with Zika.

8 Feb 2019

Scientists wean mosquitoes off blood with dieting drugs

Researchers have found a way to reduce the blood thirst of mosquitoes and prevent mosquito bites and spread of mosquito borne illnesses such as Zika, dengue fever, malaria and chikungunya.

7 Feb 2019

Mutations in folliculin gene affect embryo implantation

New information is unfolding on the genetic controls of an early turning point in pregnancy. As the tiny, dividing cell mass, the blastocyst, travels from the oviduct and lodges in the wall of the uterus, the cells must exit their pre-implantation state and be ready for post-implantation development.

7 Feb 2019

Blood-clotting factor may cause Alzheimer's disease

A protein known for its role in forming blood clots has been found to cause the characteristic cognitive decline of Alzheimer's disease.

7 Feb 2019

Scientists untangle how microbes manufacture key antibiotic compound

For decades, scientists and doctors have known that bacteria in soil were capable of manufacturing streptozotocin, an antibiotic compound that is also an important treatment for certain types of pancreatic cancer.

7 Feb 2019

Binge drinking in adolescence causes lasting changes in emotional center of brain

Binge drinking in adolescence has been shown to have lasting effects on the wiring of the brain and is associated with increased risk for psychological problems and alcohol use disorder later in life.

7 Feb 2019

NSAID pretreatment promotes cardiorenal syndrome in heart failure

Non-steroidal anti-inflammatory drugs, or NSAIDs, are widely known as pain-killers and can relieve pain and inflammation. However, prolonged use raises the risk of heart and kidney failure events. A heart attack causes death of heart muscle cells by lack of oxygen, and it also significantly injures the kidneys.

7 Feb 2019

Researchers show efficacy of new therapy for amyotrophic lateral sclerosis in mice

A team from Université Laval and the CERVO Brain Research Centre has demonstrated the efficacy in mice of a new therapy that addresses the main manifestation of amyotrophic lateral sclerosis.

7 Feb 2019

New study pinpoints how fibrosis develops in butterfly syndrome patients

Children with a grave skin disorder known as butterfly syndrome develop severe and chronic blisters. Fibrosis, the thickening and scarring of connective tissues, is a major complication of the disease.

7 Feb 2019

Hibernation spurts of hamsters hold clues to better treatments for Alzheimer's disease

Syrian hamsters are golden-haired rodents often kept as house pets. Cold and darkness can cause the animals to hibernate for 3-4 days at a time, interspersed with short periods of activity.

7 Feb 2019

A new treatment for Chlamydia via Canadian researchers

A new way to prevent and treat one of the commonest sexually transmitted infections (STIs) has been developed by the researchers at the University of Manitoba and the University of Waterloo. This new method is more of a gene therapy than antibiotic therapy against the infection.

6 Feb 2019

Simulation model to find the most optimal cancer treatment

In ten years, computers will be able to propose the most suitable cancer treatment for you. The idea is to simulate how all possible combinations of existing cancer treatments will work on your particular tumor.

6 Feb 2019

Drug cocktail may help combat breast cancer

MYC, a gene with high cancer-initiating potential, is overexpressed in over 40% of breast cancers. While MYC programs breast cancer cells to build more macromolecules (anabolic metabolism) it also creates a metabolic vulnerability by making them more sensitive to a type of cell death known as apoptosis.

6 Feb 2019

Researchers develop new way to prevent and treat Chlamydia

Researchers at the University of Waterloo have developed a new way to prevent and treat Chlamydia, the most common sexually transmitted bacterial infection in the world.

6 Feb 2019

Advanced scan shows brain inflammation related to post-treatment Lyme disease syndrome

More than 1 in 10 people successfully treated with antibiotics for Lyme disease go on to develop chronic, sometimes debilitating, and poorly understood symptoms of fatigue and brain fog that may last for years after their initial infection has cleared up.

6 Feb 2019