Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Wayne State's College of Engineering receives $1.7 million to develop novel insulin delivery system

Diabetes is a chronic disease that occurs when the pancreas does not produce enough insulin -- a hormone that regulates blood sugar -- or the body cannot effectively use the insulin it produces. According to the Diabetes Research Institute Foundation, the disease is increasing at an alarming rate in the United States, with an estimated 30.3 million people currently with diabetes.

12 Dec 2019

Researchers examine p53-deficient colon cancer cells to identify how p53 impacts metabolic adaptation

Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the tumor. Statins, which are often prescribed to lower cholesterol, block this metabolic pathway and cause the cancer cells to die, as scientists from the German Cancer Research Center have now discovered.

12 Dec 2019

Researchers aim to improve oral delivery of insulin for diabetes patients

Diabetes is a chronic disease that occurs when the pancreas does not produce enough insulin -- a hormone that regulates blood sugar-- or the body cannot effectively use the insulin it produces.

12 Dec 2019

Extensive tumor protein analysis reveals potential new players in cancer

Looking to gain a deeper understanding of cancer, a team led by researchers at Baylor College of Medicine conducted an extensive computational analysis of the similarities and differences in the entire set of proteins, called the proteome, of more than 500 cancers from five different tissue sites.

12 Dec 2019

New software to help researchers study specific information about proteins

What if scientists could create more effective drugs to treat cancers and other diseases by better targeting specific sites on proteins in the body?

11 Dec 2019

Yale scientists flip the script on novel cancer therapy to find new insights into lupus

In the last decade, scientists discovered that blocking a key regulator of the immune system helped unleash the body's natural defenses against several forms of cancer, opening up a new era of cancer immunotherapy.

11 Dec 2019

Epigenome editing could repair genetic brain disorder

A new study published in the journal Nature Communications shows that it may be possible to reverse gene mutations that cause brain disorders, using a very precisely targeted epigenome editing technique. This type of gene editing does not change the gene’s DNA sequence itself but is focused on correcting epigenome changes only. The condition that was corrected in the study is called the WAGR syndrome and is associated with obesity and intellectual disability in people.

11 Dec 2019

Study reveals mechanism that helps pancreatic cancer cells avoid starvation

A new study reveals the mechanism that helps pancreatic cancer cells avoid starvation within dense tumors by hijacking a process that pulls nutrients in from their surroundings.

11 Dec 2019

Genetic code doesn't dictate whether a person is guaranteed to develop Alzheimer's

The colour of our eyes or the straightness of our hair is linked to our DNA, but the development of Alzheimer's disease isn't exclusively linked to genetics, suggest recently published findings.

11 Dec 2019

Researchers test vaccine strategy for chronic inflammatory diseases

Chronic inflammatory bowel diseases, such as Crohn's Disease and ulcerative colitis, are linked to abnormalities of the gut microbiota in humans and in animals. Patients generally present reduced bacterial diversity in their intestinal flora along with excessive levels of bacteria that express a protein called flagellin, which favors their mobility.

11 Dec 2019

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Huntington's disease (HD) is an incurable and fatal hereditary disease. Developing disease-modifying drugs to treat patients with HD depends on studying them in animal models. Scientists evaluated the mouse models used for developing new treatments for mood disorders in HD and recommended which of these models are most relevant to their studies.

11 Dec 2019

Study could help improve GENUS to become a therapeutic approach for Alzheimer's disease

The sweeping extent to which increasing 40Hz "gamma" rhythm power in the brain can affect the pathology and symptoms of Alzheimer's disease in mouse models has been surprising, even to the MIT neuroscientists who've pioneered the idea. So surprising, in fact, they can't yet explain why it happens.

11 Dec 2019

Study sheds light on the factors at play in neuroblastoma metastasis

Neuroblastoma can grow and spread in the body very aggressively, making it very difficult to treat. New research has shed important light on the factors at play in the metastasis of neuroblastoma, which could potentially lead to new treatment strategies.

11 Dec 2019

New approach to alter intestinal microbiota and protect against inflammatory diseases

Targeted immunization against bacterial flagellin, a protein that forms the appendage that enables bacterial mobility, can beneficially alter the intestinal microbiota, decreasing the bacteria's ability to cause inflammation and thus protecting against an array of chronic inflammatory diseases, according to a new study by the Institute for Biomedical Sciences and the Neuroscience Institute at Georgia State University.

11 Dec 2019

Genetic variant mainly found in individuals of African ancestry increases odds of heart failure

A genetic variant in the gene transthyretin (TTR)- which is found in about 3 percent of individuals of African ancestry- is a more significant cause of heart failure than previously believed, according to a multi-institution study led by researchers at Penn Medicine.

10 Dec 2019

Intermittent fasting may provide significant health benefits, study shows

Intermittent fasting may provide significant health benefits, including improved cardiometabolic health, improved blood chemistry and reduced risk for diabetes, new research conducted in part at Texas State University indicates.

10 Dec 2019

Tulane study focuses on treatment of preeclampsia

A Tulane University researcher has received a grant that will support the development of new imaging methods to improve the treatment of preeclampsia.

10 Dec 2019

Researchers find another piece of puzzle relating to bird flu viruses

Normally, bird flu viruses do not spread easily from person to person. But if this does happen, it could trigger a pandemic. Researchers from the MDC and RKI have now explained in the journal Nature Communications what makes the leap from animals to humans less likely.

10 Dec 2019

Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

Cystic fibrosis is caused by an inherited mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

10 Dec 2019

Immunotherapy more effective than chemotherapy for children, young adults with relapsed B-ALL

New findings from a clinical trial show that treatment with the immunotherapy drug blinatumomab is superior to standard chemotherapy for children and young adults with high- or intermediate-risk B-cell acute lymphoblastic leukemia that has relapsed.

10 Dec 2019

Protein News and Research

Further Reading

Wayne State's College of Engineering receives $1.7 million to develop novel insulin delivery system

Researchers examine p53-deficient colon cancer cells to identify how p53 impacts metabolic adaptation

Researchers aim to improve oral delivery of insulin for diabetes patients

Extensive tumor protein analysis reveals potential new players in cancer

New software to help researchers study specific information about proteins

Yale scientists flip the script on novel cancer therapy to find new insights into lupus

Epigenome editing could repair genetic brain disorder

Study reveals mechanism that helps pancreatic cancer cells avoid starvation

Genetic code doesn't dictate whether a person is guaranteed to develop Alzheimer's

Researchers test vaccine strategy for chronic inflammatory diseases

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Study could help improve GENUS to become a therapeutic approach for Alzheimer's disease

Study sheds light on the factors at play in neuroblastoma metastasis

New approach to alter intestinal microbiota and protect against inflammatory diseases

Genetic variant mainly found in individuals of African ancestry increases odds of heart failure

Intermittent fasting may provide significant health benefits, study shows

Tulane study focuses on treatment of preeclampsia

Researchers find another piece of puzzle relating to bird flu viruses

Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

Immunotherapy more effective than chemotherapy for children, young adults with relapsed B-ALL

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