Genes News and Research

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Study details exactly how Her2 gene promotes progression and spread of breast cancer cells

Research led by Dr. Suresh Alahari, the Fred Brazda Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans and its Stanley S. Scott Cancer Center, details exactly how the Her2 cancer gene promotes the progression and spread of breast cancer cells.

23 Jan 2013

Novel way to engineer specialized immune cells targeted by the AIDS virus

Researchers at the Stanford University School of Medicine have found a novel way to engineer key cells of the immune system so they remain resistant to infection with HIV, the virus that causes AIDS.

23 Jan 2013

Studies identify cellular pathways involved in governing day-night pattern of circadian rhythms

UC Irvine-led studies have revealed the cellular mechanism by which circadian rhythms - also known as the body clock - modify energy metabolism and also have identified novel compounds that control this action. The findings point to potential treatments for disorders triggered by circadian rhythm dysfunction, ranging from insomnia and obesity to diabetes and cancer.

23 Jan 2013

UB scientists propose first genomic explanation for schizophrenia

New University at Buffalo research demonstrates how defects in an important neurological pathway in early development may be responsible for the onset of schizophrenia later in life.

23 Jan 2013

Antibodies essential for dendritic cell maturation

Dendritic cells, or DCs for short, perform a vital role for the immune system: They engulf pathogens, break them down into their component parts, and then display the pieces on their surface.

23 Jan 2013

SLU team discovers molecular pathway that contributes to triple-negative breast cancer

In research published in the Jan. 17 issue of The Journal of Cell Biology, a team led by Susana Gonzalo, Ph.D., assistant professor of biochemistry and molecular biology at Saint Louis University, has discovered a molecular pathway that contributes to triple-negative breast cancer, an often deadly and treatment resistant form of cancer that tends to strike younger women.

23 Jan 2013

Family members with rare gene mutation at high risk of developing schizophrenia

Johns Hopkins researchers have identified a rare gene mutation in a single family with a high rate of schizophrenia, adding to evidence that abnormal genes play a role in the development of the disease.

22 Jan 2013

Scientists discover role of OTUD7B enzyme as TRAF3's protector

Marked for death with molecular tags that act like a homing signal for a cell's protein-destroying machinery, a pivotal enzyme is rescued by another molecule that sweeps the telltale targets off in the nick of time.

21 Jan 2013

Scientists identify a possible lead in treatment of two childhood leukemia subtypes

Research led by St. Jude Children's Research Hospital scientists has identified a possible lead in treatment of two childhood leukemia subtypes known for their dramatic loss of chromosomes and poor treatment outcomes.

21 Jan 2013

Mature CD4+ helper T lymphocytes can be re-programed to gain killing functions

The fate of mature T lymphocytes might be a lot more flexible than previously thought. New research from the RIKEN Center for Allergy and Immunology (RCAI) in Japan and La Jolla Institute for Allergy and Immunology (LIAI) in the USA shows for the first time that mature CD4+ helper T lymphocytes can be re-programed to become killer-like CD8+ T lymphocytes and gain killing functions.

21 Jan 2013

Researchers identify clear role for tags in mediating genetic risk for rheumatoid arthritis

In one of the first genome-wide studies to hunt for both genes and their regulatory "tags" in patients suffering from a common disease, researchers have found a clear role for the tags in mediating genetic risk for rheumatoid arthritis (RA), an immune disorder that afflicts an estimated 1.5 million American adults.

21 Jan 2013

G-quadruplexes also exist within the human genome

In 1953, Cambridge researchers Watson and Crick published a paper describing the interweaving 'double helix' DNA structure - the chemical code for all life.

21 Jan 2013

Law banning genetic discrimination doesn't apply to some insurers

NPR examines a key loophole in the law designed to keep health insurers from raising rates or denying coverage because of genetic issues. The law doesn't apply to life, disability or long-term-care insurance.

19 Jan 2013

Intestinal bacteria can produce biochemicals and hormones that stop development of diabetes

All humans have enormous numbers of bacteria and other micro-organisms (10 to 14) in the lower intestine. In fact our bodies contain about ten times more bacteria than our own cells and these tiny passengers are extremely important for our health. They help us digest our food and provide us with energy and vitamins.

19 Jan 2013

Scientists figure out how to dodge HPV-triggered cancers by vaccination

In 2009, more than 30,000 people in the U.S. learned they had cancer linked to the human papillomavirus, or HPV. This virus is best known for causing cervical cancer, but it's also the culprit behind many cancers of the mouth, throat, anus, and genitals. Unlike many forms of cancer, for which we lack the knowledge and tools to prevent, scientists have figured out how to dodge HPV-triggered cancers — by HPV vaccination.

19 Jan 2013

NSU to host conference on neuro immune conditions

Nova Southeastern University (NSU) will be hosting a conference on Saturday, Jan. 26 about the upcoming opening of the NSU College of Osteopathic Medicine's Institute for Neuro Immune Medicine.

19 Jan 2013

New model of tau pathology spread

Brain diseases associated with the misformed protein tau, including Alzheimer's disease and frontotemporal lobar degeneration with tau pathologies, are characterized by neurofibrillary tangles (NFTs) comprised of pathological tau filaments.

19 Jan 2013

Stress in adolescence can cause severe mental illness in young adulthood

Working with mice, Johns Hopkins researchers have established a link between elevated levels of a stress hormone in adolescence — a critical time for brain development — and genetic changes that, in young adulthood, cause severe mental illness in those predisposed to it.

18 Jan 2013

Sabutoclax appears to selectively target leukemia stem cells that are responsible for relapses

Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms are sensitive - and thus vulnerable - to a novel cancer stem cell-targeting drug currently under development.

18 Jan 2013

RSAS honors Feinstein Institute scientist with Crafoord Prize for genetic research on arthritis

The Royal Swedish Academy of Sciences announced today that Peter K. Gregersen , MD, a scientist at The Feinstein Institute for Medical Research, will receive the prestigious Crafoord Prize for his genetic research in the area rheumatoid arthritis.

18 Jan 2013

Genes News and Research

Study details exactly how Her2 gene promotes progression and spread of breast cancer cells

Novel way to engineer specialized immune cells targeted by the AIDS virus

Studies identify cellular pathways involved in governing day-night pattern of circadian rhythms

UB scientists propose first genomic explanation for schizophrenia

Antibodies essential for dendritic cell maturation

SLU team discovers molecular pathway that contributes to triple-negative breast cancer

Family members with rare gene mutation at high risk of developing schizophrenia

Scientists discover role of OTUD7B enzyme as TRAF3's protector

Scientists identify a possible lead in treatment of two childhood leukemia subtypes

Mature CD4+ helper T lymphocytes can be re-programed to gain killing functions

Researchers identify clear role for tags in mediating genetic risk for rheumatoid arthritis

G-quadruplexes also exist within the human genome

Law banning genetic discrimination doesn't apply to some insurers

Intestinal bacteria can produce biochemicals and hormones that stop development of diabetes

Scientists figure out how to dodge HPV-triggered cancers by vaccination

NSU to host conference on neuro immune conditions

New model of tau pathology spread

Stress in adolescence can cause severe mental illness in young adulthood

Sabutoclax appears to selectively target leukemia stem cells that are responsible for relapses

RSAS honors Feinstein Institute scientist with Crafoord Prize for genetic research on arthritis

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