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Alzheimer's pathophysiology shows racial disparities

A study has identified racial disparities between African-Americans and Caucasians in the way in which Alzheimer’s disease arises and develops.

7 Jan 2019

Newly discovered biomarkers can help identify heart condition in patients who have three 'clinical risks'

Researchers at the University of Birmingham have found two biomarkers that could be used to identify a heart condition known as atrial fibrillation in patients who have three 'clinical risks'.

7 Jan 2019

New, potential therapy can disrupt myeloid cells that promote tumor growth

Cancerous tumors trick myeloid cells, an important part of the immune system, into perceiving them as a damaged part of the body; the tumors actually put myeloid cells to work helping them grow and metastasize (spread).

7 Jan 2019

Common food additive could cause celiac disease, review says

Research suggests that celiac disease could be caused by a bacterial enzyme used to manufacture sausages, cheese, bread and other processed foods.

7 Jan 2019

Inhalable mRNA offers hope for patients with lung disease

Scientists have reported the success of an inhalable mRNA therapy that can induce the production of a target protein in the lungs of mice.

4 Jan 2019

A small protein plays key role in how cancer stem cells differentiate

A jagged little protein appears to be key to how cancer stem cells differentiate and enable metastasis, according to researchers at Rice University and the Duke University School of Medicine.

4 Jan 2019

Researchers develop new method of analysis to map cellular locations of proteins

Researchers at Karolinska Institutet and SciLifeLab have developed a new method of analysis that maps the location of proteins in the cell. The information has been compiled in a database that is accessible to researchers around the world.

3 Jan 2019

Commonly prescribed ADHD drug unlikely to increase cardiovascular risks in children

With more than 1.8 million children in the U.S. being treated annually with drugs for attention deficit hyperactivity disorder, the possibility that such drugs could damage their hearts has been a significant cause of concern for parents and physicians alike.

3 Jan 2019

Bulldogs' screw tails linked to rare inherited syndrome in humans

With their small size, stubby faces and wide-set eyes, bulldogs, French bulldogs and Boston terriers are among the most popular of domestic dog breeds. Now researchers at the University of California, Davis, School of Veterinary Medicine have found the genetic basis for these dogs' appearance, and linked it to a rare inherited syndrome in humans.

3 Jan 2019

Fruit fly study sheds light on the evolution of metabolism

Diet choice of animal species is highly variable. Some are specialists feeding only on one food source, such as a sugar-rich fruit or protein-rich meat. Other species, like humans, are generalists that can feed on different kinds of food sources.

3 Jan 2019

New medications provide better treatment for alcohol use disorders, chronic pain, mood disorders

Helping people with addictions has become a research passion for Purdue University's Richard van Rijn, who is leading a team to make drug discoveries to support millions around the world dealing with alcohol use disorders, chronic pain and mood disorders.

3 Jan 2019

Researchers reveal cause of possible genetic problems in mitochondria

A group of researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine has revealed the importance of eliminating any excess of defective products that might have accumulated in the mitochondria, as its presence generates mitochondrial instability and information loss on the mitochondrial genome.

3 Jan 2019

Study provides new insight into generation of new neurons in adulthood

Researchers at Sahlgrenska Academy at the University of Gothenburg, Sweden, in collaboration with research groups in Finland, Canada, and Slovenia, have discovered a novel and unexpected function of nestin, the best known marker of neural stem cells.

3 Jan 2019

Alzheimer’s Disease: Learning from the Past, Looking to the Future

An interview with Dr. Lloyd Tran, discussing the major barriers to Alzheimer’s research and development over the past 40 years.

From Alzheimer International Society 3 Jan 2019

Study: Mice lacking PARL protein display specific problems in the nervous system reminiscent of Leigh syndrome

Leuven researchers led by professor Bart De Strooper (VIB-KU Leuven) have identified a new role for PARL, a protein that has been linked to Parkinson's disease.

3 Jan 2019

ERADA launches first diagnostic saliva test for malaria

ERADA Technology Alliance Ltd, pioneers of innovative, rapid diagnostic solutions for early detection of infectious diseases, have announced the imminent launch of a world first diagnostic saliva test for malaria.

2 Jan 2019

Scientists cast new light on function of long-mysterious PCSK9 mutation

High levels of low-density lipoproteins, parcels of lipids and protein that carry cholesterol, are a leading risk factor for heart disease. Many cholesterol medications lower LDL, some of them by targeting the protein PCSK9. In the January issue of the Journal of Lipid Research, scientists at the University of California, San Francisco, report on an investigation into why experiments on PCSK9 give different results in a test tube and in liver cells.

2 Jan 2019

Study provides new insights into how genes are activated

In a study in Nature, researchers at Karolinska Institutet present a new method for analyzing how instructions in the genome control how our genes are activated in individual cells.

2 Jan 2019

Rockefeller scientists uncover genetic mutation responsible for tuberculosis vulnerability

If you live in the United States, you are unlikely to come into contact with the microbe that causes tuberculosis. Your odds of encountering the microbe are so low, in fact, that risk factors for the disease can easily go unnoticed: If you happened to carry a gene that predisposed you to tuberculosis, you likely wouldn't know.

2 Jan 2019

Study reveals heart cell defect as possible cause of heart failure in pregnancy

Peripartum cardiomyopathy is a rare form of heart failure that affects women in their last month of pregnancy and up to five months after giving birth. PPCM can be difficult to detect because its symptoms -- swelling in the feet and legs and shortness of breath -- mimic many of those of third trimester pregnancy.

2 Jan 2019