Protein C News and Research

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Using Assay Kits and Dyes to Advance Cell Biology Research

In this interview, Richard Delle Bovi highlights live cell ability of the CELLESTIAL® analysis kit from Enzo Life Sciences and its applications in cell biology.

From Enzo Life Sciences, Inc. 2 Jan 2019

Study uncovers how tumors backfire on neoadjuvant chemotherapy

Some patients with breast cancer receive chemotherapy before the tumor is removed with surgery. This approach, called 'neoadjuvant' therapy, helps to reduce the size of the tumor to facilitate breast-conserving surgery, and can even eradicate the tumor, leaving few or no cancerous cells for the surgeon to remove.

2 Jan 2019

New insights on cellular death mechanisms caused by the loss of neuronal cells and astrocytes

The blood circulation to neurons is affected due to Ischemic, hemorrhagic stroke and subarachnoid hemorrhage stimulation the activation of pathophysiological responses i.e. mitochondrial death pathways, protein misfolding, apoptosis, pyroptosis, necrosis, autophagy, mitophagy, ferritinophagy, excitotoxicity, free radicals release, and inflammation.

31 Dec 2018

Research reviews role of protein tyrosine phosphatase in molecular biology

As the proteomics technology develops and human genomic analysis becomes easier to execute, molecules involved in the regulation of biochemical signaling pathways have become interesting subjects for researchers.

28 Dec 2018

Review of recent advances in label-free quantification in cancer proteomics

In recent years, proteomics research has become a popular method for characterizing the functional proteins driving the transformation of malignancy, tracing the large-scale protein alterations induced by anti-cancer drug, as well as discovering the innovative targets and first-in-class drugs for oncologic disorders.

28 Dec 2018

MUSC researchers link higher levels of AGEs to ER-positive breast cancer risk

Poor diet and lack of exercise are associated with cancer development, but the underlying biology is not well understood. Advanced glycation end products could offer a biological link to help us understand how certain lifestyle behaviors increase cancer risk or lessen the likelihood that an anti-cancer therapy will be effective.

28 Dec 2018

Study finds how long-term memory encoded engram neurons are formed

While long-term memory is known to be encoded in specific neural cells, engram neurons, it has been unclear how these engram neurons are formed during training.

28 Dec 2018

New research tests Co-enzyme Q10 as potential treatment for Chronic Kidney disease

Chronic Kidney disease is highly associated with all-cause mortality, Diabetic Nephropathy, cardiovascular events and hospitalization whether the patient has an existing risk or current cardiovascular disease or not.

28 Dec 2018

Scientists gain new insight into aggressive breast cancers

Scientists from Cardiff University have uncovered a protein which drives aggressive breast cancer and could be targeted for developing new and improved therapies.

27 Dec 2018

Study uncovers how skin ages, loses fat and immunity

Dermal fibroblasts are specialized cells deep in the skin that generate connective tissue and help the skin recover from injury. Some fibroblasts have the ability to convert into fat cells that reside under the dermis, giving the skin a plump, youthful look and producing a peptide that plays a critical role in fighting infections.

27 Dec 2018

Neuronal cell death in Alzheimer's disease may actually not be a bad thing, shows study

For the first time, scientists at the Champalimaud Centre for the Unknown, in Lisbon, Portugal, have shown that neuronal cell death in Alzheimer's disease may actually not be a bad thing - on the contrary, it may be the result of a cell quality control mechanism trying to protect the brain from the accumulation of malfunctioning neurons.

27 Dec 2018

Breast cancer drugs could tackle lung cancers resistant to targeted therapies

A class of drugs used to treat certain breast cancers could help to tackle lung cancers that have become resistant to targeted therapies, suggests a new study in mice from the Francis Crick Institute and the Institute of Cancer Research.

27 Dec 2018

Study: Reactivation of HIV-infected cells depends on its size and cell cycle

Thanks to the development of antiretroviral drugs, human immunodeficiency virus is considered a manageable chronic disease today.

27 Dec 2018

NIPER researcher presents a review on autophagy in neuronal cells

Autophagy is a cellular degradation process that can cause the death of a cell in certain conditions. Autophagy is necessary to maintain cellular homeostasis by clearing out damaged cellular organelles and proteins through certain pathways.

27 Dec 2018

Lupin partners with Abbvie to develop and commercialize new targeted oncology treatments

Pharma major Lupin Limited and global biopharmaceutical company AbbVie Inc., today announced that AbbVie has licensed Lupin's MALT1 (Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1) inhibitor program.

25 Dec 2018

New mechanism may explain neurons shrinking in Huntington's disease

A hallmark of neurodegenerative diseases like Huntington's is the progressive death of nerve cells in the brain. The cells don't die quickly, though. They first start to disconnect from each other because their neurites -- long finger-like extensions that make connections all through the brain -- become smaller.

25 Dec 2018

Scientists discover two therapies that slow progression of pediatric leukemia in mice

Northwestern Medicine scientists have discovered two successful therapies that slowed the progression of pediatric leukemia in mice, according to three studies published over the last two years in the journal Cell, and the final paper published Dec. 20 in Genes & Development.

24 Dec 2018

FDA authorizes marketing of new tool to aid in nutritional management of breast milk

Today, the U.S. Food and Drug Administration permitted marketing of the Miris Human Milk Analyzer, a new diagnostic test to aid healthcare professionals in measuring nutrients in breast milk, including the concentration of fat, carbohydrate, protein, total solids and energy.

24 Dec 2018

Glial cell maturation is severely impaired in patients with Huntington's disease

The neurological disorder Huntington's disease causes behavioral and motor changes, which among other things are a result of dysfunctional maturation or formation of glial cells, the brain's support cells, researchers from the University of Copenhagen demonstrate in a new study based on mice trials.

24 Dec 2018

Study reveals how molecular mechanisms regulate lysosomal exocytosis by phagocytes

Lysosomes are filled with more than 50 different hydrolytic enzymes, which are capable of digesting most cellular components.

23 Dec 2018

Protein C News and Research

Using Assay Kits and Dyes to Advance Cell Biology Research

Study uncovers how tumors backfire on neoadjuvant chemotherapy

New insights on cellular death mechanisms caused by the loss of neuronal cells and astrocytes

Research reviews role of protein tyrosine phosphatase in molecular biology

Review of recent advances in label-free quantification in cancer proteomics

MUSC researchers link higher levels of AGEs to ER-positive breast cancer risk

Study finds how long-term memory encoded engram neurons are formed

New research tests Co-enzyme Q10 as potential treatment for Chronic Kidney disease

Scientists gain new insight into aggressive breast cancers

Study uncovers how skin ages, loses fat and immunity

Neuronal cell death in Alzheimer's disease may actually not be a bad thing, shows study

Breast cancer drugs could tackle lung cancers resistant to targeted therapies

Study: Reactivation of HIV-infected cells depends on its size and cell cycle

NIPER researcher presents a review on autophagy in neuronal cells

Lupin partners with Abbvie to develop and commercialize new targeted oncology treatments

New mechanism may explain neurons shrinking in Huntington's disease

Scientists discover two therapies that slow progression of pediatric leukemia in mice

FDA authorizes marketing of new tool to aid in nutritional management of breast milk

Glial cell maturation is severely impaired in patients with Huntington's disease

Study reveals how molecular mechanisms regulate lysosomal exocytosis by phagocytes

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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