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$Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction$

Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction

Researchers at the University of Arizona have discovered that metformin, a drug commonly used to treat type 2 diabetes, might also be used to treat heart failure with preserved ejection fraction, a condition that is predicted to affect over 8% of people ages 65 or older by the year 2020.

19 Dec 2018

MUSC researchers identify potential therapeutic target for lung fibrosis

In an article published online by Frontiers in Endocrinology, researchers at the Medical University of South Carolina report that they have identified a potential therapeutic target for lung fibrosis or scarring.

19 Dec 2018

Galectins play a key role in the degeneration of cartilage in osteoarthritis

A network of carbohydrate binding proteins - so-called galectins - plays an important role in the degeneration of cartilage in osteoarthritis.

19 Dec 2018

Personalization techniques give a new lease of life to anticancer vaccines

Anticancer vaccines have gained a new lease of life with techniques to personalise them to individual patients.

19 Dec 2018

HPV discovery could lead to new treatments for cervical cancer

Researchers at the University of Virginia School of Medicine have made a discovery about human papillomavirus that could lead to new treatments for cervical cancer and other cancers caused by the virus.

19 Dec 2018

Study reveals how stem cells can be induced to differentiate into various ocular lineages

The discovery of pluripotent stem cells, which have the ability to differentiate into the huge range of different cell lineages that make up the human body, signaled the start of a new era in biological science and medicine. Although we are also now able to reprogram regular cells to exhibit this pluripotency, we still have much to learn about the different cues that lead such cells towards a particular cell fate, including the cells that make up the eye.

19 Dec 2018

Researchers aim to improve cognition, reverse weight gain in schizophrenia

Aerobic exercise can improve the size and function of the brain, and now investigators want to know if it can also improve cognitive function in patients with schizophrenia who struggle with memory and attention problems.

19 Dec 2018

Hepatitis C drug can eliminate chikungunya, yellow fever virus

A study performed at the University of São Paulo's Biomedical Science Institute (ICB-USP) in Brazil shows that sofosbuvir, a drug used to treat chronic hepatitis C, is capable of eliminating chikungunya virus and yellow fever virus.

19 Dec 2018

Gut microbiome plays role in immune system regulation, study finds

Scientist have long known that bacteria in the intestines, also known as the microbiome, perform a variety of useful functions for their hosts, such as breaking down dietary fiber in the digestive process and making vitamins K and B7.

19 Dec 2018

Novel insight on inflammatory regulation could pave way for effective pain therapies

A novel way in which the inflammatory response to pain is regulated has been described in the open-access journal eLife.

19 Dec 2018

Decoding chemical and other sensory cues that drive infanticide

It may seem like one of the cruelest aspects of the natural world, but research has shown that infanticide is actually an instinctive behavior in many animals - and Catherine Dulac has begun deciphering the chemical and other sensory cues that drive the behavior.

19 Dec 2018

Study reveals how ASV and HIV-1 share similar structural features that drive membrane targeting, assembly

A key step in retroviral growth inside a cell, as described by Jamil Saad, Ph.D., and colleagues, is portrayed on the cover of The Journal of Biological Chemistry.

18 Dec 2018

New drug could significantly slow progression of ALS, shows research

A new drug could significantly slow the progression of ALS, also known as Lou Gehrig's disease, according to new research by University of Alberta biologists. Current treatments slow progression of the degenerative disease by only a few months, and these findings could revolutionize the treatment of patients suffering from ALS, extending and improving quality of life.

18 Dec 2018

New therapy for childhood blindness shows 'very promising' results

A new therapy aimed at improving the sight of people with one of the most common forms of childhood blindness, has shown 'very promising' initial results, according to a study involving UCL researchers.

18 Dec 2018

New compound blocks genetic cause of familial ALS and frontotemporal dementia

Since the ice bucket challenge went viral in 2014, raising awareness and funding for ALS research, scientists have learned much about a disease that disconnects muscles from nerves, leading to muscle atrophy and eventual death. Their ultimate goal is to create medications capable of stopping ALS in its tracks.

18 Dec 2018