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UZH researchers map spinal cord neurons involved in 'Gate Control Theory' of pain

Sensing pain is extremely unpleasant and sometimes hard to bear - and pain can even become chronic. The perception of pain varies a lot depending on the context in which it is experienced. 50 years ago, neurobiologist Patrick Wall and psychologist Ronald Melzack formulated the so-called "Gate Control Theory" of pain.

20 Mar 2015

New in vitro study examines benefits of pear-enriched diet on chronic diseases

A new in vitro (test tube) study, "Dietary functional benefits of Bartlett and Starkrimson pears for potential management of hyperglycemia, hypertension and ulcer bacteria Helicobacter pylori while supporting beneficial probiotic bacterial response," was published in the March issue of Food Research International.

20 Mar 2015

Latinos continue to face problems in accessing high-quality health care

Latinos are the largest ethnic minority group in the United States, and it's expected that by 2050 they will comprise almost 30 percent of the U.S. population. Yet they are also the most underserved by health care and health insurance providers.

20 Mar 2015

Study provide new insights into why childhood CKD may worsen to kidney failure

Study results published today in the National Kidney Foundation's American Journal of Kidney Diseases provide new insights into why a child's chronic kidney disease (CKD) may worsen to kidney failure.

20 Mar 2015

Vitamin D plays major role in preventing diabetes and atherosclerosis

In recent years, a deficiency of vitamin D has been linked to type 2 diabetes and heart disease, two illnesses that commonly occur together and are the most common cause of illness and death in Western countries. Both disorders are rooted in chronic inflammation, which leads to insulin resistance and the buildup of artery-clogging plaque.

19 Mar 2015

Semler receives 510(k) marketing clearance from FDA for next generation PAD testing system

Semler Scientific, Inc., an emerging medical risk assessment company that develops, manufactures and markets patented products that assist healthcare providers in monitoring patients and evaluating chronic diseases, today announced receipt of 510(k) marketing clearance from the U.S. Food and Drug Administration for its next generation peripheral artery disease (PAD) testing system.

19 Mar 2015

New pre-clinical, clinical data for IMBRUVICA to be highlighted at AACR Annual Meeting

Pharmacyclics, Inc. today announced that new pre-clinical and clinical data for ibrutinib (IMBRUVICA) will be highlighted at the 2015 American Association for Cancer Research Annual Meeting to be held April 18 – 22, 2015, in Philadelphia, PA.

19 Mar 2015

BCM-95 Curcumin improves chemotherapy's effectiveness in killing chemoresistant cancer cells

Cancer cell resistance to chemotherapy is a major cause of death in patients with colorectal cancer. In a first-of-its-kind study, BCM-95 Curcumin was found to improve chemotherapy's effectiveness in killing chemoresistant cells via a mechanism not previously identified.

19 Mar 2015

Daiichi Sankyo signs co-commercialization agreement with AstraZeneca for MOVANTIK (naloxegol)

Daiichi Sankyo, Inc. today announced a co-commercialization agreement with AstraZeneca for MOVANTIK (naloxegol) in the US, in line with the Daiichi Sankyo strategy to expand its US portfolio through strategic alliances, in addition to internal R&D and acquisitions.

19 Mar 2015

Cardiovascular researchers identify MG53 protein necessary for repairing injured kidney cells

Cardiovascular researchers at The Ohio State University Wexner Medical Center have shown that a protein known as MG53 is not only present in kidney cells, but necessary for the organ to repair itself after acute injury. Results from this animal model study are published in the journal Science Translational Medicine.

19 Mar 2015

Health care changes essential to manage chronic disease, say researchers

Chronic disease accounts for 7 of every 10 deaths in the United States and more than 75% of total health care costs. Among people 65 years old and older, over 92% suffer from one or more chronic diseases.

19 Mar 2015

TxCell to receive US patent for Ovasave to treat inflammatory bowel disease

TxCell SA, a biotechnology company developing innovative, cost-effective, personalized T cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, today announces that a key patent is to be granted on March 31 2015 by the United States Patent and Trademark Office.

19 Mar 2015

People with severe schizophrenia have major differences in brain networks

People with a severe form of schizophrenia have major differences in their brain networks compared to others with schizophrenia, bipolar disorder and healthy individuals, a new study from the Centre for Addiction and Mental Health shows.

19 Mar 2015

Oxygen wristbands: an interview with Dr Gillian Lowrey

Oxygen is delivered with variable flows that administer different concentrations. National guidelines were published in 2009 that provide recommendations about prescribing the oxygen and titrating it to certain target ranges.

18 Mar 2015

New research lays groundwork for developing treatments for asthma, COPD

In diseases such as asthma and chronic obstructive pulmonary disease (COPD), the body produces too much mucus, making breathing difficult. New research from Washington University School of Medicine in St. Louis provides clues to potentially counteract inappropriate mucus production.

18 Mar 2015

Finding could improve global efforts to prevent HIV transmission, save lives

People who recently have been infected with HIV may not be as highly infectious as previously believed, a finding that could improve global efforts to prevent HIV transmission and save lives. In particular, the finding bolsters the strategy of treating patients with antiretroviral drugs before the onset of AIDS to prevent transmission.

18 Mar 2015

Kansas State doctoral student selected to attend prestigious Lindau Nobel Laureate Meeting

A Kansas State University doctoral student will spend part of her summer interacting with Nobel laureates in physics, physiology, medicine and chemistry.

18 Mar 2015

Researchers identify promising new approach to treat pulmonary fibrosis

By uncovering the mechanism by which fibrous tissue cells in the lung multiply, researchers at The Saban Research Institute of Children's Hospital Los Angeles, along with colleagues in Mexico and Canada, have identified a promising new approach for the treatment of pulmonary fibrosis.

18 Mar 2015

NCCN panelists discuss on evidence-based decision-making at bedside

On Friday, March 13, 2015, as part of its 20th Annual Conference: Advancing the Standard of Cancer Care, the National Comprehensive Cancer Network hosted its second roundtable, Value-Based Decision-Making at the Bedside, which reflected on the tools available to oncology clinicians, such as clinical practice guidelines and pathways, and how the use of these tools has impacted bedside evidence-based decision-making for both physicians and patients, the criteria used to assess shared decision-making, and the relationship between outcomes and cost when determining value.

18 Mar 2015

Study investigates effects of antidepressant treatment in pain catastrophizing patients

A select population of patients having surgery experience what is called pain catastrophizing - an irrational thought process that leads a patient to perceive pain as worse than it actually is. Antidepressant medications reduce negative mood and might change this way of thinking, but according to a study published in the April edition of Anesthesiology, the official medical journal of the American Society of Anesthesiologists, that may not be the case, at least for acute pain.

18 Mar 2015

Chronic News and Research

UZH researchers map spinal cord neurons involved in 'Gate Control Theory' of pain

New in vitro study examines benefits of pear-enriched diet on chronic diseases

Latinos continue to face problems in accessing high-quality health care

Study provide new insights into why childhood CKD may worsen to kidney failure

Vitamin D plays major role in preventing diabetes and atherosclerosis

Semler receives 510(k) marketing clearance from FDA for next generation PAD testing system

New pre-clinical, clinical data for IMBRUVICA to be highlighted at AACR Annual Meeting

BCM-95 Curcumin improves chemotherapy's effectiveness in killing chemoresistant cancer cells

Daiichi Sankyo signs co-commercialization agreement with AstraZeneca for MOVANTIK (naloxegol)

Cardiovascular researchers identify MG53 protein necessary for repairing injured kidney cells

Health care changes essential to manage chronic disease, say researchers

TxCell to receive US patent for Ovasave to treat inflammatory bowel disease

People with severe schizophrenia have major differences in brain networks

Oxygen wristbands: an interview with Dr Gillian Lowrey

New research lays groundwork for developing treatments for asthma, COPD

Finding could improve global efforts to prevent HIV transmission, save lives

Kansas State doctoral student selected to attend prestigious Lindau Nobel Laureate Meeting

Researchers identify promising new approach to treat pulmonary fibrosis

NCCN panelists discuss on evidence-based decision-making at bedside

Study investigates effects of antidepressant treatment in pain catastrophizing patients

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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