Antifungal News and Research

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Study shows how microbes influence the quality of sausage and other fermented foods

Microbes in "starter cultures" impart a distinctive tang and longer shelf life to food like sourdough bread, yogurt and kimchi through the process of fermentation.

6 Aug 2020

Three commercially available drugs may cause unexpected effects in humans, shows study

A new study of 1,443 medications found that three prescription drugs currently on the market caused unexpected changes in worms that could point to potential, unrecognized effects in humans.

28 Jul 2020

Neurotransmitter-derived lipidoids help carry drugs across the blood-brain barrier in mice

Biomedical engineers at the Tufts University School of Engineering have developed tiny lipid-based nanoparticles that incorporate neurotranmitters to help carry drugs, large molecules, and even gene editing proteins across the blood-brain barrier and into the brain in mice.

24 Jul 2020

New fabrics prevent the transmission and spread of SARS-CoV-2

Brazilian textile companies have begun producing and marketing fabrics treated with silver and silica nanoparticles developed by the research groups at the Centre for Functional Materials (CDMF) and the Theoretical and Computational Chemistry Laboratory (QTC) at the Universitat Jaume I, in collaboration with the company Nanox Tecnologia, which provide the new fabrics with antibacterial, antifungal and antiviral properties with 99.99% effectiveness.

20 Jul 2020

New method spurs production of antibiotic or antiparasitic compounds in actinobacteria

Researchers have developed a method to spur the production of new antibiotic or antiparasitic compounds hiding in the genomes of actinobacteria, which are the source of drugs such as actinomycin and streptomycin and are known to harbor other untapped chemical riches.

25 Jun 2020

Researchers solve structure of key enzyme critical for biofilm formation in fungal pathogen

Aspergillus fumigatus is a species of fungus that can cause serious illnesses in immunocompromised individuals such as those who are undergoing transplantation or cancer chemotherapy.

17 Jun 2020

Genetic marker may predispose African Americans to cardiac complications from COVID-19

Nearly one out of every 10 African Americans has a genetic variant that puts them inherently at an increased risk for ventricular arrhythmias and sudden cardiac death.

15 Jun 2020

Immune modulation can cure severe and often fatal fungal infection in children

In the June 11 issue of the New England Journal of Medicine, a team of UCLA physicians and scientists describes the first case of immune modulation being used to cure a severe and often fatal fungal infection.

11 Jun 2020

New antibiotic guidelines could save more lives in intensive care units

More lives could be saved in intensive care units around the world if new antibiotic guidelines designed by The University of Queensland are adopted.

8 May 2020

New drug formulation could be used in the treatment of Candida infections

With antimicrobial resistance (AMR) increasing around the world, new research led by the University of Bristol has shown a new drug formulation could possibly be used in antifungal treatments against Candida infections.

28 Apr 2020

New database of 14,000 known macrolactones could support drug discovery and research

Researchers from North Carolina State University and Collaborations Pharmaceuticals have created a free-to-use database of 14,000 known macrolactones - large molecules used in drug development - which contains information about the molecular characteristics, chemical diversity and biological activities of this structural class.

22 Apr 2020

Analysis reveals cocktail of pharmaceuticals in the waters of Bangladesh

In spring of 2019, researchers set out to investigate what chemicals could be found in the waters of Bangladesh.

20 Apr 2020

Inhibition of sphingolipid metabolism and neurodegenerative diseases

Disrupting production of sphingolipids in neurons improved neurodegeneration symptoms and increased survival in a mouse model.

13 Apr 2020

Study: Bangladesh’s surface waters have high levels of antibiotic residues, chemicals

High levels of antibiotic residues, other medicines and chemicals present in Bangladesh's ponds, canals, lakes, rivers and other surface waters are contributing to a spike in antibiotic resistance in the country, says a new study.

11 Apr 2020

Research findings could aid in the recognition and management of COVID-19 pneumonia

Researchers have identified the most common clinical characteristics of 109 patients with COVID-19 related pneumonia who died in Wuhan, China in the early stages of the coronavirus pandemic, according to a new study published online in the Annals of the American Thoracic Society.

7 Apr 2020

Researchers make breakthrough in unlocking genetic potential of ocean microbes

Researchers have made a breakthrough in developing gene-editing tools to improve understanding of an important ocean microbe.

6 Apr 2020

How cannabis interacts with medications

A new practice guideline published in the journal CMAJ in February 2020 describes five types of drug interactions possible with the use of cannabis. Cannabis is a plant-derived drug containing the psychoactive ingredient delta-9-tetrahydrocannabinol (THC) and non-psychoactive cannabidiol (CBD). These cannabinoids are broken down by the liver enzymes cytochrome P450 C(YP)34A, and CYP2CC9.

2 Mar 2020