Phosphorylation News and Research

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LJI scientists uncover how OGT enzyme keeps cells healthy

Researchers at La Jolla Institute for Immunology have at last uncovered how an enzyme called O-GlcNAc transferase (OGT) keeps cells healthy.

12 Jan 2023

MALAT1 suppression is a hallmark of tissue and peripheral proliferative T cells in COVID-19

In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom investigated lncRNA (long non-coding ribonucleic acids) expression in coronavirus disease 2019 (COVID-19) T lymphocyte transcriptomes.

10 Jan 2023

Researchers identify novel gene mechanism in most aggressive kidney cancers

In a new study from the Johns Hopkins Kimmel Cancer Center, researchers described a novel mechanism of tumor formation in kidney cancers driven by overexpression of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway with loss of the tuberous sclerosis complex (TSC) tumor suppressor gene.

3 Jan 2023

New insights on the circadian clock of Drosophila melanogaster

The higher the temperatures, the faster physiological processes are. But there is an exception: the so-called circadian clock, which regulates the sleep-wake cycle in organisms.

30 Dec 2022

Sarunashi juice and its constituting component help prevent and reduce lung cancer in mice

Lung cancer is the leading cause of death in Japan and across the globe. Among all the cancers, lung cancer has one of the lowest five-year survival rates.

28 Dec 2022

SARS-CoV-2 and human cold coronavirus OC43 inhibit stress granule formation through Nsp15 protein

Researchers investigated the mechanisms through which the human common cold Betacoronavirus OC43 (HCoV-OC43) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibit the formation of stress granules.

21 Dec 2022

UBC researchers identify a compound that shows early promise at halting viral infections

Researchers at UBC's Life Sciences Institute have identified a compound that shows early promise at halting infections from a range of coronaviruses, including all variants of SARS-CoV-2 and the common cold.

15 Dec 2022

Signaling pathway within brain cells regulates sleep

A good night's sleep can work wonders for both mind and body. But what is it that determines how much we need to sleep, and what can cause us to sleep more deeply?

12 Dec 2022

Research reveals the assembly dynamics of nucleocapsid protein condensates can be regulated by small molecules with therapeutic potential

Researchers developed a screening platform and identified molecules with anti-CoV activity.

12 Dec 2022

Detection of filoviruses by the innate immune system

In a new study, researchers examined how the innate immune system detects filoviruses.

1 Dec 2022

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Researchers report that a gut microbial catabolite could reduce the cardiometabolic disease burden in mice.

29 Nov 2022

Study reveals a promising therapeutic target for Alzheimer's disease

In a recent search for gene variants associated with Alzheimer's disease (AD), several affected families showed a mutation in an enzyme called protein kinase C-alpha (PKCα). Family members with this mutation had AD; those without the mutation did not.

28 Nov 2022

Phosphorylation News and Research

LJI scientists uncover how OGT enzyme keeps cells healthy

MALAT1 suppression is a hallmark of tissue and peripheral proliferative T cells in COVID-19

Researchers identify novel gene mechanism in most aggressive kidney cancers

New insights on the circadian clock of Drosophila melanogaster

Sarunashi juice and its constituting component help prevent and reduce lung cancer in mice

SARS-CoV-2 and human cold coronavirus OC43 inhibit stress granule formation through Nsp15 protein

UBC researchers identify a compound that shows early promise at halting viral infections

Signaling pathway within brain cells regulates sleep

Research reveals the assembly dynamics of nucleocapsid protein condensates can be regulated by small molecules with therapeutic potential

Detection of filoviruses by the innate immune system

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Study reveals a promising therapeutic target for Alzheimer's disease

New chemical probe can selectively inhibit human COQ8A protein in cells

Flavonoids with potential to fight allergies and inflammation

Study provides a key link between the social environment and healthy brains

Single drug compound may offer a promising new strategy for treating prostate cancer patients

Utilizing marine sources to extract DHA to treat Alzheimer’s

Melatonin could be a potential therapy for long-COVID symptoms

Empty lipid nanoparticles trigger maturation and activation of antigen-presenting cells

New biomarker could aid in early diagnosis of Alzheimer’s disease

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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