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Combining toxic herbicide with sugar-binding proteins may trigger Parkinsonism

Combining low doses of a toxic herbicide with sugar-binding proteins called lectins may trigger Parkinsonism -- symptoms typical of Parkinson's disease like body tremors and slowing of body motions -- after the toxin travels from the stomach to the brain.

4 Dec 2018

Advances in gene therapy for inherited blood disorders

Gene therapy holds a lot of promise in medicine. If we could safely alter our own DNA, we might eliminate diseases our ancestors passed down to us.

4 Dec 2018

Gene that allows you eat as much as you want could help combat obesity

It sounds too good to be true, but a novel approach that might allow you to eat as much food as you want without gaining weight could be a reality in the near future.

4 Dec 2018

Researcher discovers key differences in protein production between healthy cells and tumors

The human body is made up of more than 200 types of cell, from bone and brain to liver and lung. Each cell type is determined by the particular combination of proteins it produces.

4 Dec 2018

Researchers identify promising new therapeutic target for Parkinson’s

A new study has shed light on the role fatty acids play in Parkinson’s disease and pointed towards an enzyme as a potential therapeutic target for the disease.

4 Dec 2018

Study provides new insights into mechanisms used by cells to transmit genetic information

The integrity of the genome relies on the ability of the cells to build and maintain a well-defined boundary between the nuclear compartment and the cytoplasm, known as the nuclear envelope.

4 Dec 2018

NanoBioCel group develops lipid vesicles that can genetic material efficiently and viably

In a piece of research conducted in collaboration, the NanoBioCel group of the UPV/EHU's Faculty of Pharmacy, and the University of Elche have designed some niosomes, which are lipid vesicles for use in gene therapies designed to treat diseases of the central nervous system.

4 Dec 2018

Researchers develop new technique to accurately isolate phloem cells across plants

Crops worldwide are increasingly vulnerable to pandemics, as diseases hitch rides on global flows of people and goods, hopping from continent to continent. Phloem diseases such as citrus greening are one particularly devastating group of plant diseases that have been wreaking economic havoc globally.

4 Dec 2018

Early gut bacterial colonization may reduce risk of developing eczema

Strains of a bacterium commonly found in skin infections may help to protect against eczema, according to new research in the British Journal of Dermatology.

4 Dec 2018

Clearer diagnosis of polio-like illness in young children

Johns Hopkins researchers have analyzed patient data from 45 cases of what they thought was acute flaccid myelitis, the polio-like outbreak occurring in U.S. children, and realized that only 75 percent of diagnosed cases were AFM.

4 Dec 2018

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

So-called CAR-T cell therapy is a promising option for treating around a fifth of patients with diffuse large B-cell lymphoma.

4 Dec 2018

New study shows that sambaqui societies were not ordinary hunter-gatherers

Shell middens are archeological features consisting mainly of the remains of marine animals thrown away near settlements over hundreds or thousands of years. They are the debris of human activity. In Brazil, they are known by the Tupi word sambaqui.

4 Dec 2018

International study increases group of lung cancer patients who may benefit from immunotherapy

The strategy for triggering the patient's own immune system to attack cancer, immunotherapy, is proving effective for more and more tumor types, although to varying degrees.

4 Dec 2018

Aerobic exercise may reduce risk of diabetes-related renal disease

Aerobic exercise may reduce the risk of diabetes-related kidney disease in some people, according to a new study. The findings are published ahead of print in the American Journal of Physiology--Renal Physiology and was chosen as an APS select article for December.

4 Dec 2018

Scientists use genetically engineered immune cells to fight Hodgkin and non-Hodgkin lymphoma cells

University of North Carolina Lineberger Comprehensive Cancer Center researchers reported promising early results from a clinical study of an investigational cellular immunotherapy that used a patient's own, genetically engineered immune cells to recognize and fight Hodgkin and non-Hodgkin lymphoma cells.

4 Dec 2018

New strategies may improve performance of CAR-T cell therapy in treating cancer

Mayo Clinic researchers have developed two new strategies that may improve the performance of chimeric antigen receptor therapy in treating cancer. They are presenting results of their preclinical research at the 2018 annual meeting of the American Society of Hematology in San Diego.

3 Dec 2018

New drug combination could kill melanoma cells more effectively, study shows

A class of cancer drugs called protein kinase inhibitors is one of the most effective treatments for melanoma. However, in many cases, tumors eventually become resistant to the drugs and cause a relapse in the patient.

3 Dec 2018

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

A gene mutation that is believed to have safeguarded some people in 14th century Europe from the bubonic plague today may be protecting HIV patients co-infected with hepatitis C from potentially fatal liver scarring, says a University of Cincinnati College of Medicine physician-scientist.

3 Dec 2018

Using nanocarrier-delivered microRNA to target sepsis

One in three patients who die in the U.S. dies of sepsis, according to the Centers for Disease Control and Prevention. It is one of the leading causes of death in intensive care units and, with an estimated price tag of $20 billion in 2011, the most expensive condition that hospitals treat.

3 Dec 2018

Researchers uncover genes that lead to excessive tau in dementia

Researchers have identified two major groups of genes involved in the mutations that lead to excess production of tau, a protein involved in dementia.

3 Dec 2018

Protein C News and Research

Combining toxic herbicide with sugar-binding proteins may trigger Parkinsonism

Advances in gene therapy for inherited blood disorders

Gene that allows you eat as much as you want could help combat obesity

Researcher discovers key differences in protein production between healthy cells and tumors

Researchers identify promising new therapeutic target for Parkinson’s

Study provides new insights into mechanisms used by cells to transmit genetic information

NanoBioCel group develops lipid vesicles that can genetic material efficiently and viably

Researchers develop new technique to accurately isolate phloem cells across plants

Early gut bacterial colonization may reduce risk of developing eczema

Clearer diagnosis of polio-like illness in young children

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

New study shows that sambaqui societies were not ordinary hunter-gatherers

International study increases group of lung cancer patients who may benefit from immunotherapy

Aerobic exercise may reduce risk of diabetes-related renal disease

Scientists use genetically engineered immune cells to fight Hodgkin and non-Hodgkin lymphoma cells

New strategies may improve performance of CAR-T cell therapy in treating cancer

New drug combination could kill melanoma cells more effectively, study shows

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

Using nanocarrier-delivered microRNA to target sepsis

Researchers uncover genes that lead to excessive tau in dementia

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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