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Oral methotrexate can be an effective intervention for people with knee OA

A new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of treatment with oral methotrexate, adults with primary knee osteoarthritis (OA) with inflammation had significant improvements in physical function and inflammation, a sign that this inexpensive, generic pill may be an important intervention for knee OA.

6 Nov 2020

TB screening needed for people on methotrexate who live in at-risk areas

New research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that tuberculosis (TB) screening and ongoing clinical care is needed for people on methotrexate who live in areas where the highly infectious illness is common.

6 Nov 2020

Anticoagulant drug linked to greater risk of knee and hip replacements in patients with osteoarthritis

New research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vitamin K drug widely prescribed to prevent blood clots, is associated with a significantly greater risk of knee and hip replacements in patients with osteoarthritis.

6 Nov 2020

Study opens a new avenue for prophylactic anti-malarial strategies

A new study led by Maria Manuel Mota, group leader at Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal), now shows that malaria parasites secrete the protein EXP2 that is required for their entry into hepatocytes.

6 Nov 2020

How do low levels of oxygen damage the brain?

In this interview, Professor Paul Tesar and Kevin Allan speak to News-Medical about how low levels of oxygen damage the brain.

6 Nov 2020

Researchers solve an ancient mystery that may treat neurological, blood pressure disorders

Researchers from the Swedish Defense Research Agency (FOI) and Umeå University wanted to improve the treatment of nerve agent poisoning.

6 Nov 2020

Researchers develop novel chemo-immunotherapy agent to treat pancreatic tumors

Pancreatic cancer is highly lethal: according to the National Cancer Institute, only about 10 percent of patients remain alive five years after diagnosis.

6 Nov 2020

Reducing the airborne transmission risk for SARS-CoV-2

Rapid Reviews: COVID-19 (RR:C19), an open-access overlay journal published by the MIT Press that accelerates peer review of COVID-19-related research preprints, is currently soliciting reviews of the following COVID-19 preprints.

6 Nov 2020

Unrelated mutations can lead to false-positive results in men with advanced prostate cancer

Unrelated mutations, when present in the blood, can lead to false-positive results in men with advanced prostate cancer who are undergoing liquid biopsies.

5 Nov 2020

Foods that cause inflammation tied to a higher risk of cardiovascular disease

A new study by researchers at the Harvard T.H. Chan School of Public Health has found that diets high in red and processed meat, sugary beverages, and refined grains promote inflammation in the body and increase the subsequent risk of heart disease and stroke.

5 Nov 2020

Llama antibodies could be a potent nanoweapon against COVID-19

Today in Science, researchers at the University of Pittsburgh School of Medicine describe a new method to extract tiny but extremely powerful SARS-CoV-2 antibody fragments from llamas, which could be fashioned into inhalable therapeutics with the potential to prevent and treat COVID-19.

5 Nov 2020

Report: 800 million children have dangerously high lead levels in blood

As many as 800 million children have dangerously high lead values in their blood. The neurotoxin can cause permanent brain damage.

5 Nov 2020

Researchers pioneer new approach to treating life-threatening snake bites

A new approach of treating life-threatening snake bites responsible for around 100,000 deaths globally each year is being pioneered by an international research consortium led by University of Bristol scientists.

5 Nov 2020

COVID-19 patients who experience strokes appear to have worse outcomes

People who experience strokes while infected with COVID-19 appear to be left with greater disability after the stroke, according a study led by UCL and UCLH researchers.

5 Nov 2020

HKUST researchers identify new therapeutic targets for Alzheimer's disease

Researchers at the Hong Kong University of Science and Technology have identified new therapeutic targets for Alzheimer's disease (AD) by studying the patients' brain with a newly-developed methodology.

5 Nov 2020

Stanford researchers create a highly automated device that can detect COVID-19 in 30 minutes

Throughout the pandemic, infectious disease experts and frontline medical workers have asked for a faster, cheaper and more reliable COVID-19 test.

5 Nov 2020

UCF researcher leads project to identify factors linked to preterm births among Black women

The rate of preterm births in the U.S. has been on the rise during the past six years, with a stark difference in the rate of preterm births among non-Hispanic Black women compared to non-Hispanic white women.

5 Nov 2020

Wearing a face mask during strenuous workouts does not hinder breathing

A new University of Saskatchewan study has found that exercise performance and blood and muscle oxygen levels are not affected for healthy individuals wearing a face mask during strenuous workouts.

5 Nov 2020

Antiangiogenic drugs increase the aggressiveness of some kidney tumors

Angiogenesis is the process by which tumors create new blood vessels that will provide them the nutrients to continue growing.

5 Nov 2020

Study describes the effects of a DPP3-knockout on the renin-angiotensin system

The role of the enzyme dipeptidyl peptidase 3 in the blood pressure-regulating renin-angiotensin system was investigated in the inter-university cooperation project BioTechMed-Graz. The results could pave the way for new therapies for cardio-renal diseases.

5 Nov 2020