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Researchers provide new insights into regulation of important intracellular messenger molecule

The team of prof. Joris Messens at the VIB-VUB Center for Structural Biology has provided new insights into the regulation of an important intracellular messenger molecule, hydrogen peroxide (H2O2), whose dysregulation has been linked to the development of several diseases, including cancer.

22 Nov 2018

New method enhances efficiency and accuracy of single cell RNA sequencing

In the era of personalized medicine, scientists are using new genetic and genomic insights to help them determine the best treatment for a given patient. In the case of cancer, the first step toward these treatments is an investigation into how tumor cells behave in an effort to figure out the best drugs to use to attack them.

22 Nov 2018

Discovery of new gene could lead to better understanding of human susceptibility to chemicals

The discovery of a new gene in zebrafish could lead to a better understanding of how exposure to chemicals leads to disease in humans, according to a new Oregon State University study.

22 Nov 2018

Researchers characterize new animal model that mimics aspects of AMD

Age-related macular degeneration affects roughly 200,000 individuals in the United States each year. In most, it comes on slowly, gradually blurring the central field of vision used for activities like reading and driving. While treatments exist to slow its progression, there is no cure.

22 Nov 2018

Scientists identify key protein involved in Hantavirus Pulmonary Syndrome

A global team of investigators has identified a key protein involved in Hantavirus Pulmonary Syndrome, a serious and sometimes fatal respiratory disease, according to research published today in the journal Nature.

22 Nov 2018

Breakthrough Alzheimer's discovery

A new study has found that the neurons in the brain can alter their genetic make-up unlike other cells of the body which remain constant.

22 Nov 2018

'Longevity protein' restores muscle regeneration after injury in older animals

One of the downsides to getting older is that skeletal muscle loses its ability to heal after injury. New research from the University of Pittsburgh implicates the so-called "longevity protein" Klotho, both as culprit and therapeutic target.

21 Nov 2018

Lower levels of protein make squamous carcinoma cells more invasive

Loss of a protein called TRIM29 promotes cancer cell invasion in a common type of skin cancer, suggesting a novel diagnostic marker and a possible therapeutic target.

21 Nov 2018

Researchers awarded $7 million funding in Pancreatic Cancer Collective’s 'New Therapies Challenge'

The Pancreatic Cancer Collective, the strategic partnership of the Lustgarten Foundation and Stand Up To Cancer, has awarded a total of $7 million in first-round "New Therapies Challenge" grants to seven teams of top cancer researchers to explore new pancreatic cancer treatments, the American Association for Cancer Research, the Scientific Partner of SU2C, announced today.

21 Nov 2018

New low-cost injectable hydrogel could help wounds heal faster

Researchers at the University of New Hampshire have created an easy-to-make, low-cost injectable hydrogel that could help wounds heal faster, especially for patients with compromised health issues.

21 Nov 2018

Gut protein mutations protect against spikes in blood glucose levels

Why is it that, despite consuming the same number of calories, sodium and sugar, some people face little risk of diabetes or obesity while others are at higher risk? A new study by investigators at Brigham and Women's Hospital has uncovered mutations in a gene that appear to help drive this difference.

21 Nov 2018

Scientists find evidence of prions in the eyes of CJD patients

National Institutes of Health scientists and their colleagues have found evidence of the infectious agent of sporadic Creutzfeldt-Jakob disease (CJD) in the eyes of deceased CJD patients.

21 Nov 2018

Genetic therapy may help children with Angelman syndrome to overcome seizures

Angelman syndrome is a genetic disease with no cure. Children grow up with severe intellectual disabilities and a range of other problems, arguably the worst of which are epileptic seizures. Now scientists at the UNC School of Medicine have found evidence that genetic therapy may prevent the enhanced seizure susceptibility.

21 Nov 2018

Myriad biological, societal factors that impact CKD severity for children of African descent

Myriad biological and societal factors can impact the occurrence and accelerate progression of chronic kidney disease for children of African descent - including preterm birth, exposure to toxins during gestation and lower socioeconomic status - and can complicate these children's access to effective treatments, according to an invited commentary published in the November 2018 edition of American Journal of Kidney Diseases.

21 Nov 2018

Scientists discover toxic bullet involved in bacterial competition

A bacterial toxin that allows an infectious strain of bacteria to defeat its competitors has been discovered by Imperial College London scientists.

20 Nov 2018

Study uncovers new mechanism controlling the master cancer regulator

Of the more than 23,000 genes in the human genome, only a handful assume a very central role in signal transduction and growth regulation. Of these, the three genes encoding RAS proteins are particularly important, as they are found mutated in over 25% of human cancers.

20 Nov 2018

Peanut allergies could soon have a drug treatment

Millions of individuals worldwide suffer from peanut allergies. Researchers are developing a new treatment for fighting this allergy. A clinical trial had been conducted and the results are in.

20 Nov 2018

Researchers discover new information on pathological mechanisms of Alzheimer's disease

Researchers at the University of Helsinki have discovered a mechanism by which harmful tau protein aggregates are transmitted between neurons. Alongside amyloid plaques, tau aggregates in the brain are a significant factor in the progression of Alzheimer's disease.

20 Nov 2018

'Unknown' enzyme may be key to new treatment for inflammatory diseases

An enzyme that normally repairs damaged DNA, may be the key to a new treatment for inflammatory diseases.

20 Nov 2018

Potential new therapeutic approach developed for synovial sarcoma

Scientists have developed a potential new therapeutic approach for synovial sarcoma, one of the most common soft-tissue cancers in teenagers and young adults.

20 Nov 2018