Protein C News and Research

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Researchers shed light on molecular mechanisms of heart valvular disease

About three per cent of the world's population is affected by valvular heart diseases. It is also the most common cause of heart surgery, as no drug-based treatment is available.

20 Nov 2018

DNA vaccine reduces levels of toxic proteins in Alzheimer’s model

Researchers have developed a new DNA vaccine that reduces the build-up of the toxic proteins associated with Alzheimer’s disease.

20 Nov 2018

Low-protein, high-carb diet may promote healthy brain ageing

Researchers at the University of Sydney have shown that a low-protein, high-carbohydrate diet may be the key to healthy brain ageing and longevity.

20 Nov 2018

Blocking activity of plasma protein can be possible way to protect against radiation-induced injury

It is possible to prevent certain injuries that can occur in radiation therapy against cancer. By blocking the activity of a plasma protein during and immediately after radiation, the patient can be protected against injury. This is shown in a new doctoral thesis at Umeå University, Sweden.

20 Nov 2018

Scientists identify novel target for neuron regeneration, functional recovery in spinal cord injury

Restoring the ability to walk following spinal cord injury requires neurons in the brain to reestablish communication pathways with neurons in the spinal cord.

20 Nov 2018

Scientists use cryo-EM to capture freeze-frames of molecule’s 'lock-and-load' on DNA

Pushing the limits of cryo-electron microscopy, University of California, Berkeley, scientists have captured freeze-frames of the changing shape of a huge molecule, one of the body's key molecular machines, as it locks onto DNA and loads the machinery for reading the genetic code.

20 Nov 2018

Study sheds light on the infection mechanism of influenza virus

New research has taken a step towards understanding how highly pathogenic influenza viruses such as deadly bird flu infect humans.

20 Nov 2018

New research offers hope for simpler way to diagnose and treat cancer

Monitoring cancer can often be an intrusive and exhausting process for patients. But with Brigham Young University chemistry professor Ryan Kelly's new research, there is hope for a simpler way: No more biopsies.

20 Nov 2018

Researchers identify multisystem disorder caused by bi-allelic variants in CCDC47 gene

Researchers and clinicians through a multicenter collaboration have identified a novel multisystem disorder caused by bi-allelic variants in the CCDC47 gene. Their findings are reported in the American Journal of Human Genetics.

20 Nov 2018

Location matters for inflammation clearance

Health conditions that involve inflammation run the gamut, from multiple sclerosis and lupus to arthritis, diabetes, and cancer. While inflammation can serve as a normal response to help the body deal with injury or infection, problems arise when it persists, potentially harming surrounding tissues.

20 Nov 2018

Researchers to explore the enigmatic role of unstructured protein in regulating circadian function

A new frontier in the science of circadian rhythms - whose disruption is linked to major diseases like cancer and diabetes - suggests a previously unknown mechanism at work in our daily biological cycle.

20 Nov 2018

New research project to combat obesity, type 2 diabetes receives NIH funding

A research project headed by a faculty member from the Ohio University Heritage College of Osteopathic Medicine, which will explore whether administering a protein that's produced in the body can help prevent obesity and type 2 diabetes, has received $464,145 in funding from the National Institutes of Health.

20 Nov 2018

New drug shows promise for treating people with peanut allergy

Controlled ingestion of peanut protein could help build tolerance in peanut allergy sufferers. Authors of a new study published in the New England Journal of Medicine say an oral immunotherapy drug they tested could be the first FDA-approved medication of its kind for people with peanut allergy.

19 Nov 2018

Receptor structure could be key to developing new osteoporosis drugs

Researchers at the University of Zurich have determined the three-dimensional structure of a receptor that controls the release of calcium from bones. The receptor is now one of the main candidates for developing new drugs to treat osteoporosis.

19 Nov 2018

RNAi therapy shown to alleviate preeclampsia in animal model

Researcher have used a small interfering RNA (siRNA) to reduce preeclampsia symptoms in an animal model. The approach could provide a new way of treating preeclampsia in humans.

19 Nov 2018

Researchers identify molecule to fight myotubular myopathy

Myotubular myopathy is a severe genetic disease that leads to muscle paralysis from birth and results in death before two years of age. Although no treatment currently exists, researchers from the University of Geneva, Switzerland, - working in collaboration with the University of Strasbourg, France, - have identified a molecule that not only greatly reduces the progression of the disease but also boosts life expectancy in animal models by a factor of seven.

19 Nov 2018

Study reveals impact of residual inflammatory risk on clinical outcomes after PCI

Patients who have persistently high levels of inflammation following percutaneous coronary intervention for coronary artery disease are significantly more likely to die from any cause or to have a heart attack within a year, according to a study of 7,026 patients published in the European Heart Journal.

19 Nov 2018