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Drug similar to Gleevec may help tame some brain cancers

The drug Gleevec (imatinib mesylate) is well known not only for its effectiveness against chronic myeloid leukemia (CML) and acute lymphoblastic leukemia, but also for the story behinds its development. The drug was specifically designed to target an abnormal molecule--a fusion of two normal cell proteins--that fueled a tumor's growth.

10 Feb 2015

New study shows that chronic narcotic use more prevalent in children with IBD

Chronic narcotic use is more than twice as prevalent in children with inflammatory bowel disease (IBD), compared with children without this disease, according to a new study1 published in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association.

10 Feb 2015

Scientists potentially discover new therapeutic targets to halt progression of tumor cells

Chronic inflammation is directly associated with several types of cancer, yet the reasons as to why this happens at a cellular level remain unclear. Now, an international team of scientists led by researchers at The Wistar Institute has identified a multistep process showing not only how these cancers develop but also potentially discovering new therapeutic targets that could halt the formation and progression of tumor cells.

10 Feb 2015

Five researchers selected to receive 2015 Avant-Garde Award for HIV/AIDS Research

With proposals ranging from innovative therapies to the development of unique organoid models of the brain, five scientists have been selected to receive the 2015 Avant-Garde Award for HIV/AIDS Research from the National Institute on Drug Abuse, part of the National Institutes of Health. The five scientists will each receive $500,000 per year for five years to support their research.

10 Feb 2015

Researchers document pathological progress of multiple sclerosis

The Centre for Brain Research at the MedUni Vienna is regarded as a world leader in researching the mechanisms involved with multiple sclerosis (MS). Now, in a paper published in the highly respected journal Lancet Neurology, an international team of researchers from Edinburgh, Cleveland and Vienna, under the leadership of Hans Lassmann, Head of the Department of Neuroimmunology at the MedUni Vienna, has for the first time documented the pathological progress of the disease from its early to late stage and also shown that inflammatory and neurodegenerative processes have a role to play.

9 Feb 2015

Study reveals mechanical forces that drive epithelial wound healing

A collaborative study led by scientists from the Mechanobiology Institute at the National University of Singapore has revealed the mechanical forces that drive epithelial wound healing in the absence of cell supporting environment. This research was published in Nature Communications in January 2015.

9 Feb 2015

Discovery improves understanding of factors that trigger allergic asthma

When the mucosal surfaces in the lungs of healthy people come into contact with allergenic substances, so-called regulatory T cells also known as Treg cells, are activated. These are capable of actively preventing the development of allergies.

9 Feb 2015

Prevalence of geriatric conditions among older, insured patients with diabetes vary little by ethnicity

In one of the first studies of its kind, researchers found that the prevalence of geriatric conditions and diabetic complications among older, insured patients with diabetes did not vary significantly by ethnicity.

9 Feb 2015

PE/GHTN linked to higher frequency of cardiovascular and metabolic abnormalities

In a study to be presented on Feb. 5 in an oral concurrent session at 2:45 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting™, in San Diego, researchers of the MFMU Network will present findings of long term cardiovascular and metabolic abnormalities five to ten years later in women with preeclampsia/gestational hypertension during pregnancy.

9 Feb 2015

Groundbreaking study reveals potential dangers of ice hockey for young athletes

James Hudziak, M.D., has two children who love ice hockey. His son skates for his college team and one of his daughters plays in high school.

9 Feb 2015

Study highlights the need for more research on trauma and other body-mind therapies

In a Theory and Hypothesis paper titled "Somatic Experiencing: Using Interoception and Proprioception as Core Elements of Trauma Therapy," published today in Frontiers in Psychology, Dartmouth investigators Peter Payne, SEP, and Mardi Crane-Godreau, PhD, note the lack of hypothesized scientific models for the mechanisms of action responsible for outcomes in Somatic Experiencing® (SE) trauma therapy and other body-mind therapies.

9 Feb 2015

HCV more common in West Africa yet lacks equal attention as HIV/AIDS or Ebola

More than 180 million people in the world have hepatitis C, compared with the 34 million with HIV/AIDS and the roughly 30,000 who have had Ebola.

9 Feb 2015

Salicylates drugs reduce proliferation, viability of cultured vestibular schwannoma cells

Researchers from Massachusetts Eye and Ear and the Harvard Medical School/ Massachusetts Institute of Technology's Program in Speech and Hearing Bioscience and Technology have demonstrated that salicylates, a class of non-steroidal inflammatory drugs (NSAIDs), reduced the proliferation and viability of cultured vestibular schwannoma cells that cause a sometimes lethal intracranial tumor that typically causes hearing loss and tinnitus.

9 Feb 2015

UM SOM launches ‘Program in Lung Healing’ to develop treatments for acute respiratory failure

University of Maryland School of Medicine (UM SOM) Dean E. Albert Reece, MD, PhD, MBA, and Jeffrey A. Rivest, MS, President and Chief Executive Officer of University of Maryland Medical Center (UMMC), today announced the official launch of a new "Program in Lung Healing," that will further the School's position as a national leader in research, education and clinical innovation for acute ailments of the lung and respiratory system.

9 Feb 2015

Study suggests that approaches to combating diabetes should be localized

Factors associated with the prevalence of diabetes vary by geographic region in the United States, according to new research from the Brown School at Washington University in St. Louis.

7 Feb 2015

New compound may lead to development of potential therapeutics for neuropathic pain

A new compound discovered by a team of UC Davis investigators has potent actions against production of a chemical that which is implicated in the development of chronic pain following a peripheral nerve injury in the spinal cord.

7 Feb 2015

CLL aggressiveness linked to genetic variability

The genetic variability of a tumour could be a predictor for its aggressiveness: the greater the variability in gene expression, the more aggressive the tumour is likely to be. This is the hypothesis that the CNIO Structural Biology and Biocomputing Programme, led by Alfonso Valencia, is testing, after their findings on chronic lymphocytic leukaemia (CLL), now published in the journal Genome Medicine.

6 Feb 2015

Study: Acute psychosocial stress has deleterious effect on the body's ability to modulate pain

Traffic slows to a crawl, then a stop. You are trapped in a bottleneck nightmare, and late for a meeting. The stress takes a toll on you psychologically - but your body is at risk as well, according to a Tel Aviv University researcher.

6 Feb 2015

People with TBI have significantly more difficulty with gist reasoning

A new study reveals that individuals with traumatic brain injury (TBI) have significantly more difficulty with gist reasoning than traditional cognitive tests. Using a unique cognitive assessment developed by researchers at the Center for BrainHealth at The University of Texas at Dallas, findings published Friday in the Journal of Clinical and Experimental Neuropsychology indicate that an individual's ability to "get the gist or extract the essence of a message" after a TBI more strongly predicts his or her ability to effectively hold a job or maintain a household than previously revealed by traditional cognitive tests alone.

6 Feb 2015

40% of prison and jail inmates have chronic medical problems, shows BJS survey

An estimated 40 percent of state and federal prisoners and jail inmates reported having a current chronic medical condition in the 2011–12 National Inmate Survey, the Bureau of Justice Statistics (BJS) announced today.

6 Feb 2015

Chronic News and Research

Drug similar to Gleevec may help tame some brain cancers

New study shows that chronic narcotic use more prevalent in children with IBD

Scientists potentially discover new therapeutic targets to halt progression of tumor cells

Five researchers selected to receive 2015 Avant-Garde Award for HIV/AIDS Research

Researchers document pathological progress of multiple sclerosis

Study reveals mechanical forces that drive epithelial wound healing

Discovery improves understanding of factors that trigger allergic asthma

Prevalence of geriatric conditions among older, insured patients with diabetes vary little by ethnicity

PE/GHTN linked to higher frequency of cardiovascular and metabolic abnormalities

Groundbreaking study reveals potential dangers of ice hockey for young athletes

Study highlights the need for more research on trauma and other body-mind therapies

HCV more common in West Africa yet lacks equal attention as HIV/AIDS or Ebola

Salicylates drugs reduce proliferation, viability of cultured vestibular schwannoma cells

UM SOM launches ‘Program in Lung Healing’ to develop treatments for acute respiratory failure

Study suggests that approaches to combating diabetes should be localized

New compound may lead to development of potential therapeutics for neuropathic pain

CLL aggressiveness linked to genetic variability

Study: Acute psychosocial stress has deleterious effect on the body's ability to modulate pain

People with TBI have significantly more difficulty with gist reasoning

40% of prison and jail inmates have chronic medical problems, shows BJS survey

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