Chronic Pain News and Research

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NIMH honors SUNY Downstate professor with MERIT award

Todd C. Sacktor, M.D., distinguished professor of physiology and pharmacology and of neurology at SUNY Downstate Medical Center, has received a MERIT (Method to Extend Research in Time) award from the National Institute of Mental Health (NIMH) for his research on memory.

7 Apr 2012

Tonix completes TNX-102 pharmacokinetic study on fibromyalgia syndrome

Tonix Pharmaceuticals Holding Corp., a specialty pharmaceutical company developing therapies for challenging disorders of the central nervous system completed a pharmacokinetic (PK) study of the first formulation of its lead drug, TNX-102, for the treatment of fibromyalgia syndrome.

6 Apr 2012

TLR4/MD-2 protein complex triggers morphine-induced inflammation

A University of Colorado Boulder-led research team has discovered that two protein receptors in the central nervous system team up to respond to morphine and cause unwanted neuroinflammation, a finding with implications for improving the efficacy of the widely used painkiller while decreasing its abuse potential.

3 Apr 2012

Nektar commences dosing in NKTR-192 Phase 1 clinical study for treatment of acute pain

Nektar Therapeutics announced today that the first subjects were dosed last week in a Phase 1 clinical study to evaluate the pharmacokinetics and safety of NKTR-192, the company's novel short-acting mu-opioid analgesic candidate.

2 Apr 2012

Long delays for persistent pain management

An article in the Australian Medical Journal reveals that taxpayers are paying $34 billion a year to treat persistent pain. Pain specialist Dr Timothy Semple, and president of the Australian Pain Society, told the Herald Sun chronic back pain, arthritis, nerve injuries and people who needed care after surviving cancer made up significant numbers.

1 Apr 2012

DBS allows surgeons to control tremors with brain 'pacemaker'

For nearly 30 years, Tom Rogers' left hand would shake when he tried to use it, making even simple tasks such as drinking a glass of water, writing a check, or making a sandwich challenging. The tremor eventually became so disruptive that he lost use of his dominant hand. Rogers sought care and learned that his tremor was a symptom of Parkinson's disease, yet felt he was suffering from something different.

27 Mar 2012

Study identifies major gene affecting chronic pain sensitivity

Nearly one in five people suffers from the insidious and often devastating problem of chronic pain.

27 Mar 2012

Nerve pain patients in Wales gain access to first of a kind treatment which can provide lasting pain relief

For the first time NHS patients in Wales with peripheral nerve pain (known as peripheral neuropathic pain) can be treated with a patch containing capsaicin, which can provide at least 12 weeks pain relief following a single 30- or 60-minute application.

25 Mar 2012

Nearly three in five Kentuckians believe pain is just a part of life

New research released today finds that pain affects the majority of Kentuckians, yet most underestimate its severity and the need for effective treatment. The survey by the American Osteopathic Association (AOA) uncovered that nearly three in five Kentuckians believe pain is just a part of life and two in five don't believe it can be eased with proper treatment.

23 Mar 2012

Antidepressants can play a key role in relieving pain associated with OA

Antidepressants can play a key role in alleviating painful conditions like osteoarthritis and may result in fewer side effects than traditionally prescribed drug regimes, such as anti-inflammatories and opioids, according to a perspective paper published online ahead of print publication by the International Journal of Clinical Practice.

22 Mar 2012

AADR honors University of Maryland scientist for pain research

Ronald Dubner, PhD, DDS, of the University of Maryland School of Dentistry was honored today with the 2012 Distinguished Scientist Award by the American Association for Dental Research.

22 Mar 2012

Scientists reveal first-ever glimpse of complete kappa opioid receptor structure

At the molecular level, drugs like salvinorin A (the active ingredient of the hallucinogenic plant Salvia divinorum) work by activating specific proteins, known as receptors, in the brain and body.

22 Mar 2012

QRxPharma, Actavis enter License and Option Agreement

QRxPharma Limited announced today execution of its License and Option Agreement with Actavis, Inc. which finalised the legal terms and conditions to commercialise MoxDuo IR in the US acute pain marketplace. The LOA completion follows a 20 December 2011 signing of a binding Letter of Intent secured by a US$6 million non-refundable upfront signing fee to QRxPharma.

19 Mar 2012

Study identifies primary care skills and competencies in opioid risk management

Primary care physicians are faced with treating a large proportion of chronic pain patients, but many do not often have specific training in the assessment and management of chronic pain, including the use of opioid medications for chronic pain management.

17 Mar 2012

$Health Canada grants license to Medtronic DBS Therapy for refractory epilepsy$

Health Canada grants license to Medtronic DBS Therapy for refractory epilepsy

Medtronic, Inc. today announced that it has received from Health Canada a license for Medtronic Deep Brain Stimulation (DBS) Therapy for refractory epilepsy patients.

From Medtronic 16 Mar 2012

More women need regular checks for Chlamydia infection: CDC

According to new figures from the Centers for Disease Control and Prevention (CDC), not many young, sexually active women in the United States are getting screened for chlamydia.

15 Mar 2012

Back pain and school children's backpacks

Significant numbers of teens regularly carry rucksacks for school which top 10 to 15 per cent of their body weight and risk back pain and other related disorders, finds research published online in the Archives of Disease in Childhood.

15 Mar 2012

The two sides of pain

"Pain is both a curse and a blessing", says Jürgen Sandkühler, Head of the Department of Neurophysiology at the Centre for Brain Research at the MedUni Vienna ahead of the international "Brain Awareness Week", being held from the 12th to the 16th of March. On the one hand, pain has an important protective function for humans.

14 Mar 2012

FDA panel favors continued research on novel pain medicine

A panel of experts for the U.S. Food and Drugs Administration (FDA) this Monday recommended that the federal government should allow continued testing of an experimental class of pain drugs for arthritis, despite links to bone decay and joint failure.

13 Mar 2012

BDSI announces postponement of ONSOLIS U.S. relaunch

BioDelivery Sciences International, Inc. today announced that the U.S. relaunch of ONSOLIS (fentanyl buccal soluble film) is being postponed until the product formulation can be modified to address two appearance issues raised by the U.S. Food and Drug Administration (FDA) following a recent inspection of the Aveva manufacturing facility where ONSOLIS is produced.

12 Mar 2012