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How to improve your chromatin immunoprecipitation experiments

Chromatrap® has published a comprehensive Applications Compendium that includes hints and tips to improve your Chromatin Immunoprecipitation (ChIP) experiments, increase the effectiveness of your ChIP-seq library preparation and brings together its latest application notes in one informative document.

From Chromatrap® - Porvair Sciences Ltd 27 Oct 2016

Mitochondria regulates stem cell proliferation in gut epithelium, study shows

What happens in intestinal epithelial cells during a chronic illness? Basic research conducted at the Chair of Nutrition and Immunology at the Technical University of Munich addressed this question by generating a new model system.

27 Oct 2016

TSRI scientists discover key molecular player in inherited disorder and morphine addiction

In a remarkable "two for one" discovery, scientists from the Florida campus of The Scripps Research Institute have illuminated a key molecular player in the addictive effects of morphine in animal models.

27 Oct 2016

Study reveals potential therapeutic targets for treating patients who carry IFNGR receptor mutation

The study began by taking the medical history of 11 children, all of whom had a disorder due to mycobacteria infections, as the basis. All were discovered to have the same phenotype with the same mutation, which was located in the interferon-gamma (IFNGR) receptor, so the group began to explore what was causing this dysfunction.

27 Oct 2016

Study reveals way to actively reverse anesthetic-induced unconsciousness

The latest study from a Massachusetts General Hospital/Massachusetts Institute of Technology team investigating the mechanisms underlying general anesthesia finds that stimulating a specific group of neurons in mice produces signs of arousal -- including getting on their feet and walking -- even as the animals continue to receive the anesthetic drug isoflurane.

27 Oct 2016

New technique shows promise for therapeutic reversal of food allergies

"This discovery reverses food allergies in mice, and we have many people with allergies volunteering their own cells for us to use in lab testing to move this research forward," said professor John Gordon, lead scientist behind the discovery just published in the current issue of the Journal of Allergy and Clinical Immunology.

27 Oct 2016

Scientists identify commonly affected genes sets among people with three mental disorders

Studying brain tissue from deceased donors, Johns Hopkins scientists have found common groups of genes disrupted among people with schizophrenia, bipolar disorder and major depression.

26 Oct 2016

Researchers receive grant to investigate how gut microbiome influences breast cancer

Researchers from the University of Illinois at Chicago and the University of Chicago have received a three-year, $900,000 Defense Department grant to investigate how the gut microbiome – the trillions of bacteria, viruses and other bugs that make our digestive systems their home – influences breast cancer.

26 Oct 2016

Gene therapy may be effective method for treating Niemann-Pick disease, type C1

For the first time, National Institutes of Health researchers have demonstrated in mice that gene therapy may be the best method for correcting the single faulty gene that causes Niemann-Pick disease, type C1 (NPC1).

26 Oct 2016

Wearable patch shows promise for treating children with peanut allergy

A wearable patch that delivers small amounts of peanut protein through the skin shows promise for treating children and young adults with peanut allergy, with greater benefits for younger children, according to one-year results from an ongoing clinical trial.

26 Oct 2016

Yale researchers use new gene editing technique to correct mutations that cause thalassemia

A Yale-led research team used a new gene editing strategy to correct mutations that cause thalassemia, a form of anemia.

26 Oct 2016

Iron fortification can reduce blood lead levels, study shows

Lead is a toxic heavy metal that was added to petrol for use in cars until as recently as 25 years ago. It is particularly harmful to the developing brains of infants, children and teenagers, and the damage it does is irreversible.

26 Oct 2016

Researchers identify genetic risk factor for binge eating

Researchers have identified a gene (CYFIP2) associated with binge eating. This finding represents one of the first examples of a genome-wide significant genetic factor to be identified for binge eating in model organisms or humans.

26 Oct 2016

People's diet linked to political change

Apparently, a richer diet is associated with an increase in the middle class, which tends towards economic and political independence and democracy-fostering values.

26 Oct 2016

CSIC project aims to study new genetic regulatory mechanisms in pathogenic bacteria

A project led by the Spanish National Research Council (CSIC) researcher, Alejandro Toledo-Arana, at the Institute of Agro biotechnology (a centre shared between CSIC, the Public University of Navarra and The Regional Government of Navarra), is studying new genetic regulatory mechanisms in pathogenic bacteria.

26 Oct 2016

Benefit and harm of tandem mass spectrometry screening for tyrosinaemia type 1 remain unclear

Tyrosinaemia type 1 is a rare, hereditary metabolic disease that, if left untreated, can already lead to serious liver and kidney damage in infancy.

25 Oct 2016

Adding whole eggs to salad can boost Vitamin E absorption, study shows

Adding whole eggs to a colorful salad boosts the amount of Vitamin E the body absorbs from the vegetables, according to research from Purdue University.

25 Oct 2016

IU scientists find evidence for link between prostate cancer and Ewing's sarcoma

Medical researchers at Indiana University Bloomington have found evidence for a link between prostate cancer, which affects millions of men age 50 and older, and Ewing's sarcoma, a rare form of cancer that affects children and young adults.

25 Oct 2016

New drug appears to decrease inflammation in the brain linked to Alzheimer's disease

An experimental drug shows promise in treating Alzheimer's disease by preventing inflammation and removing abnormal protein clumps in the brain that are associated with the disease, suggests a study in mice presented at the ANESTHESIOLOGY 2016 annual meeting.

25 Oct 2016

Novel C. elegans worm strain could serve as tool for testing interventions against AD

Researchers from Yale-NUS College have partnered with researchers from the National University of Singapore and SingHealth Group to develop a novel Caenorhabditis elegans (C. elegans) worm strain which expresses an amyloid beta protein fragment involved in the development of human Alzheimer's Disease (AD).

25 Oct 2016

G Protein News and Research

How to improve your chromatin immunoprecipitation experiments

Mitochondria regulates stem cell proliferation in gut epithelium, study shows

TSRI scientists discover key molecular player in inherited disorder and morphine addiction

Study reveals potential therapeutic targets for treating patients who carry IFNGR receptor mutation

Study reveals way to actively reverse anesthetic-induced unconsciousness

New technique shows promise for therapeutic reversal of food allergies

Scientists identify commonly affected genes sets among people with three mental disorders

Researchers receive grant to investigate how gut microbiome influences breast cancer

Gene therapy may be effective method for treating Niemann-Pick disease, type C1

Wearable patch shows promise for treating children with peanut allergy

Yale researchers use new gene editing technique to correct mutations that cause thalassemia

Iron fortification can reduce blood lead levels, study shows

Researchers identify genetic risk factor for binge eating

People's diet linked to political change

CSIC project aims to study new genetic regulatory mechanisms in pathogenic bacteria

Benefit and harm of tandem mass spectrometry screening for tyrosinaemia type 1 remain unclear

Adding whole eggs to salad can boost Vitamin E absorption, study shows

IU scientists find evidence for link between prostate cancer and Ewing's sarcoma

New drug appears to decrease inflammation in the brain linked to Alzheimer's disease

Novel C. elegans worm strain could serve as tool for testing interventions against AD

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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