Genetic Engineering News and Research

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Protein imbalances within cells can cause ovarian cancer

Cancer can be caused solely by protein imbalances within cells, a study of ovarian cancer has found. The discovery is a major breakthrough because, until now, genetic aberrations have been seen as the main cause of almost all cancer.

28 Jul 2015

Study reveals impact of patient navigator program on no-show rates for cervical cancer screening

Researchers at Harvard Medical School and Brigham and Women's Hospital reported a 20% decline in the rate of missed appointments for cervical cancer evaluation following a Pap smear when a patient navigator program was initiated at the referral center.

25 Jul 2015

Researchers show how genetic modification of mouse strains complicate biomedical research interpretation

Investigators affiliated with VIB and UGent recently achieved great success with a study involving biomedical research on mouse models.

25 Jul 2015

Endocrine Society selects 18 endocrinologists as winners of 2016 Laureate Awards

The Endocrine Society today announced it has chosen 18 accomplished endocrinologists as winners of the organization's prestigious 2016 Laureate Awards.

24 Jul 2015

New UTMB study reveals mechanism central to pollen-induced allergies

A new study from The University of Texas Medical Branch at Galveston has uncovered a mechanism that is central to becoming allergic to ragweed pollen and developing allergic asthma or seasonal nasal allergies. The findings are currently available online in the American Journal of Respiratory Cell and Molecular Biology.

23 Jul 2015

Zinc coating of galvanized steel pipes can be long-term source of lead in water

When unsafe levels of lead are found in drinking water, the culprit has typically been lead pipes or lead-containing brass and bronze fittings, but in a new study researchers clearly show that lead present in the zinc coating of galvanized steel pipes can be a very significant long-term source of lead in water.

23 Jul 2015

Patients' own genetically engineered immune cells show significant success against multiple myeloma

In recent years, immunotherapy has emerged as a promising treatment for certain cancers. Now this strategy, which uses patients' own immune cells, genetically engineered to target tumors, has shown significant success against multiple myeloma, a cancer of the plasma cells that is largely incurable.

21 Jul 2015

New study reveals highly promising approach to coating tissue engineered constructs

A new study showing the ability to apply a thin coating of viable respiratory epithelial cells to tissue engineered constructs using a commercially available spray device is especially promising for therapeutic approaches in development to repair or replace challenging structures such as trachea or bronchi.

15 Jul 2015

Acupuncture can be more effective in treatment of dermatologic conditions

Medical evidence supports the potential for acupuncture to be significantly more effective in the treatment of dermatologic conditions such as dermatitis, pruritus, and urticaria than alternative treatment options, "placebo acupuncture," or no treatment, according to a review of the medical literature published in the Journal of Alternative and Complementary Medicine, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

15 Jul 2015

Novel gene therapy control system regulates expression of therapeutic transgenes

Korean researchers have described a novel control system to regulate the expression of a therapeutic transgene by targeting the passenger strand of a microRNA (miR-122) linked to the transgene.

14 Jul 2015

New understanding of keratin 17 protein could lead to development of better ways to prevent cancer

New research from the Johns Hopkins Bloomberg School of Public Health suggests that the protein keratin 17 - the presence of which is used in the lab to detect and stage various types of cancers - is not just a biomarker for the disease, but may play a critical role in tumor growth.

14 Jul 2015

Proof-of-concept addresses ongoing controversy regarding presence of oil at the bottom of Gulf of Mexico

A first of its kind study that modeled oil slick weathering over time in a laboratory setting provides evidence that evaporation combined with sinking of the heavy components of surface-spill slicks can explain the presence of oil on the sea floor.

9 Jul 2015

Evidence-based initiative aims to prevent avoidable hospital readmissions

A statewide effort led by key stakeholders in South Carolina successfully organized and implemented an evidence-based initiative aimed at improving the quality of healthcare transitions after hospital discharge to prevent avoidable readmissions.

8 Jul 2015

News study shows pregnancy complications tied to future cardiovascular disease risk

According to a new study, women can accurately recall key pregnancy-related information at least 4 years later that could have important implications for their future risk of developing cardiovascular disease (CVD).

8 Jul 2015

UC researcher awarded NCI grant to study effect of MED1 protein on HER2-positive breast cancer

Xiaoting Zhang, PhD, associate professor in the Department of Cancer Biology at the University of Cincinnati College of Medicine, has received a $1.8 million, five-year, R01 award (R01CA197865) from the National Cancer Institute to continue breast cancer research focusing on the function of the protein MED1 on HER2-positive breast cancer.

8 Jul 2015

City of Hope researchers to use patients' own modified T cells to treat advanced brain tumors

Already pioneers in the use of immunotherapy, City of Hope researchers are now testing the bold approach to cancer treatment against one of medicine's biggest challenges: brain cancer. This month, they will launch a clinical trial using patients' own modified T cells to fight advanced brain tumors.

7 Jul 2015

Findings reveal new pathway to develop effective treatments and therapies for asthma, allergy

Investigators have discovered the precise molecular steps that enable immune cells implicated in certain forms of asthma and allergy to develop and survive in the body. The findings from Weill Cornell Medical College reveal a new pathway that scientists could use to develop more effective treatments and therapies for the chronic lung disorder.

7 Jul 2015

Discovery reveals possibility of using water for finer analysis of the brain's functioning

To observe the brain in action, scientists and physicians use imaging techniques, among which functional magnetic resonance imaging (fMRI) is the best known. These techniques are not based on direct observations of electric impulses from activated neurons, but on one of their consequences. Indeed, this stimulation triggers physiological modifications in the activated cerebral region, changes that become visible by imaging.

3 Jul 2015

FDA accepts Adaptimmune’s IND application for MAGE-A10 T therapeutic candidate to combat NSCLC

Adaptimmune Therapeutics plc, a clinical stage biopharmaceutical company focused on the use of T-cell therapy to treat cancer, today announced that the U.S. Food and Drug Administration has accepted the Company's investigational new drug (IND) application for autologous genetically modified T-cells expressing enhanced T cell receptors specific for MAGE A10 (MAGE-A10 T) in patients with locally advanced or metastatic non-small cell lung cancer, and that the IND is now active.

2 Jul 2015

Live imaging study reveals link between wound-associated inflammation and skin cancer risk

Researchers in the United Kingdom and Denmark have studied the "see-through" larvae of zebrafish to reveal how wound healing leads to skin cancer. Live imaging shows neutrophils, the protective inflammatory cells of the body's immune system, diverted from an induced wound to any nearby precancerous skin cells.

1 Jul 2015

Genetic Engineering News and Research

Protein imbalances within cells can cause ovarian cancer

Study reveals impact of patient navigator program on no-show rates for cervical cancer screening

Researchers show how genetic modification of mouse strains complicate biomedical research interpretation

Endocrine Society selects 18 endocrinologists as winners of 2016 Laureate Awards

New UTMB study reveals mechanism central to pollen-induced allergies

Zinc coating of galvanized steel pipes can be long-term source of lead in water

Patients' own genetically engineered immune cells show significant success against multiple myeloma

New study reveals highly promising approach to coating tissue engineered constructs

Acupuncture can be more effective in treatment of dermatologic conditions

Novel gene therapy control system regulates expression of therapeutic transgenes

New understanding of keratin 17 protein could lead to development of better ways to prevent cancer

Proof-of-concept addresses ongoing controversy regarding presence of oil at the bottom of Gulf of Mexico

Evidence-based initiative aims to prevent avoidable hospital readmissions

News study shows pregnancy complications tied to future cardiovascular disease risk

UC researcher awarded NCI grant to study effect of MED1 protein on HER2-positive breast cancer

City of Hope researchers to use patients' own modified T cells to treat advanced brain tumors

Findings reveal new pathway to develop effective treatments and therapies for asthma, allergy

Discovery reveals possibility of using water for finer analysis of the brain's functioning

FDA accepts Adaptimmune’s IND application for MAGE-A10 T therapeutic candidate to combat NSCLC

Live imaging study reveals link between wound-associated inflammation and skin cancer risk

Genetics & Genomics - Second Edition eBook

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