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Liquid biopsies could help identify, track bladder cancer and peripheral nerve tumors

Liquid biopsies detect tumor DNA in blood or urine samples. Two studies led by Washington University School of Medicine in St. Louis describe the potential of liquid biopsies to identify and track tumor growth in two very different cancers: bladder cancer and peripheral nerve tumors.

31 Aug 2021

Blood test could enable early detection of cancer in people with neurofibromatosis type 1

People with an inherited condition known as neurofibromatosis type 1, or NF1, often develop non-cancerous, or benign, tumors that grow along nerves. These tumors can sometimes turn into aggressive cancers, but there hasn't been a good way to determine whether this transformation to cancer has happened.

31 Aug 2021

New, one-stop method developed to avoid de novo genetic disease in embryos

De novo variants (DNVs), genetic mutations that were not previously identifiable in the family history of one of two prospective parents, may cause disease in any children they have.

31 Aug 2021

Study reveals measures to tackle musical COVID-19 transmission

As the COVID-19 pandemic swept the globe in 2020, musicians around the world were desperate for the answers to two pressing questions: Can playing musical instruments transmit COVID-19? And if so, what can be done?

28 Aug 2021

Research analyzes the role of RNA tags in Alzheimer’s disease

Understanding the role of tau protein in Alzheimer's disease (AD) has led to new ways to diagnose it as well as the creation of medicines now in clinical trials to treat it.

28 Aug 2021

Ultrasound-based technology for measuring brain pressure could replace surgery

A new invention may be on the verge of replacing a costly cranial surgical procedure currently being performed on some traffic accident victims and other patient groups. The ultrasound-based technology has now been granted CE approval for the European market.

28 Aug 2021

FDA approves drug-free stroke rehabilitation system to treat upper extremity motor deficits

The U.S. Food and Drug Administration today approved the MicroTransponder Vivistim Paired VNS System (Vivistim System), a first-of-its-kind, drug-free rehabilitation system intended to treat moderate to severe upper extremity motor deficits associated with chronic ischemic stroke—a stroke caused by a blockage of blood flow to the brain with long-lasting symptoms—using vagus nerve stimulation (VNS).

27 Aug 2021

Neuroinflammation is the key upstream mechanism in Alzheimer’s disease progression

Neuroinflammation is the key driver of the spread of pathologically misfolded proteins in the brain and causes cognitive impairment in patients with Alzheimer's disease, researchers from the University of Pittsburgh School of Medicine reveal in a paper published today in Nature Medicine.

26 Aug 2021

Restoring DAXX protein levels may prevent misfolding of rogue proteins known to drive Alzheimer's

For the first time, Penn Medicine researchers showed how restoring levels of the protein DAXX and a large group of similar proteins prevents the misfolding of the rogue proteins known to drive Alzheimer's and other neurodegenerative diseases, as well as certain mutations that contribute to cancers.

26 Aug 2021

Athletes with history of concussions may show subtle and chronic brain changes

A new study suggests athletes with a history of concussion may show more brain injury from a later concussion, particularly in middle regions of the brain that are more susceptible to damage, when compared to athletes with no history of concussion.

26 Aug 2021

Aerobic exercise combined with tDCS improves the gait of Parkinson's patients

Transcranial direct current stimulation (tDCS) can increase the benefits of aerobic exercise and improve the gait of patients with Parkinson's disease immediately after a session. Step time variability decreases, reaction time shortens, and executive control of gait is enhanced.

25 Aug 2021

Two studies on gastrointestinal stroma tumors describe advances that may lead to new treatments

Gastrointestinal stroma tumors (GIST) are cancers that start in specialized nerve cells found in the digestive system, from the esophagus and stomach to the intestines and rectum.

25 Aug 2021

Researchers identify a brief window of opportunity to prevent NF1-associated optic pathway glioma

Researchers at Children's National Hospital identified a vulnerability in a developmental signaling pathway that can be hijacked to drive pediatric low-grade glioma (pLGG) formation, according to a pre-clinical study published in Developmental Cell.

23 Aug 2021

New mouse line reveals the state of protein balance in the mammalian brain for the first time

Proteins are the "tools" of our cells – they are essential to all vital tasks. However, they are only able to do their jobs if they fold correctly and adopt their respective, very specific 3D structure.

20 Aug 2021

Scientists uncover previously unknown brain mechanism behind compulsive alcohol use

A small group of nerve cells in the brain determines whether an individual continues to consume alcohol even when it has negative consequences. This is the conclusion of a study carried out on rats by researchers at Linköping University.

19 Aug 2021

New discovery offers several approaches to fight visceral obesity

Pioneering mouse study offers new therapeutic avenues for reducing visceral fat stores, which have been associated with cardiovascular disease and multiple types of cancer.

18 Aug 2021

Scientists identify the main components driving amyloid beta-associated synapse degeneration

Healthy adult brains are endowed with a vast number of synapses, structures that relay signals across nerve cells to enable communications, information processing and storage throughout the nervous system.

18 Aug 2021

Lyme disease linked to increased risk of mental disorders, suicidality

In a new study, U.S. and Danish researchers report that patients who received a hospital diagnosis of Lyme disease—inpatient, outpatient, or at the ER—had a 28 percent higher rate of mental disorders and were twice as likely to have attempted suicide post-infection, compared to individuals without the diagnosis.

17 Aug 2021

Simple roundworm may hold the key to understanding cell death processes

A biologist at The University of Texas at Arlington hopes that a simple roundworm might hold the key to understanding novel cell death processes. Such knowledge could lead to improved therapies to treat a variety of conditions in humans, including cancer and neurological injuries.

14 Aug 2021

Researchers identify genetic program in fruit fly that protects neurons from degeneration

Researchers at the University of Bonn have identified a previously unknown genetic program in the fruit fly. The genetic material involved controls the development of the neurons while also protecting them from degeneration.

13 Aug 2021

Nerve News and Research

Liquid biopsies could help identify, track bladder cancer and peripheral nerve tumors

Blood test could enable early detection of cancer in people with neurofibromatosis type 1

New, one-stop method developed to avoid de novo genetic disease in embryos

Study reveals measures to tackle musical COVID-19 transmission

Research analyzes the role of RNA tags in Alzheimer’s disease

Ultrasound-based technology for measuring brain pressure could replace surgery

FDA approves drug-free stroke rehabilitation system to treat upper extremity motor deficits

Neuroinflammation is the key upstream mechanism in Alzheimer’s disease progression

Restoring DAXX protein levels may prevent misfolding of rogue proteins known to drive Alzheimer's

Athletes with history of concussions may show subtle and chronic brain changes

Aerobic exercise combined with tDCS improves the gait of Parkinson's patients

Two studies on gastrointestinal stroma tumors describe advances that may lead to new treatments

Researchers identify a brief window of opportunity to prevent NF1-associated optic pathway glioma

New mouse line reveals the state of protein balance in the mammalian brain for the first time

Scientists uncover previously unknown brain mechanism behind compulsive alcohol use

New discovery offers several approaches to fight visceral obesity

Scientists identify the main components driving amyloid beta-associated synapse degeneration

Lyme disease linked to increased risk of mental disorders, suicidality

Simple roundworm may hold the key to understanding cell death processes

Researchers identify genetic program in fruit fly that protects neurons from degeneration

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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