Protein C News and Research

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Maverick immune cells can act independently to identify and kill cancer cells, finds research

Immune cells called Gamma Delta T cells can act independently to identify and kill cancer cells, defying the conventional view of the immune system, reveals new research from the Francis Crick Institute and King's College London.

12 Nov 2018

Inexpensive and effective drug does not reduce major adverse cardiovascular event rates

When it comes to reducing inflammation to decrease the risk of heart disease and stroke, results from the much-anticipated Cardiovascular Inflammation Reduction Trial indicate that targeting the right inflammatory pathways in at-risk patients is crucial.

12 Nov 2018

Mild exposure to single blast can induce meaningful pathogenic effects, study shows

As many as 300,000 United States service members deployed to Iraq and Afghanistan since 2001 have suffered traumatic brain injury due to explosions. The vast majority of these blast-induced traumatic brain injuries, or bTBIs, were classified as mild.

12 Nov 2018

Salk researchers receive $19.2 million to unravel mysteries of age-related cognitive decline

A team of Salk Institute researchers led by President Rusty Gage has been awarded $19.2 million over eight years by the American Heart Association-Allen Initiative in Brain Health and Cognitive Impairment to investigate mechanisms underlying Alzheimer's disease and aging-related cognitive decline and uncover new therapies.

12 Nov 2018

UCI researchers accelerate and simplify directed evolution bioengineering technique

In a process known as directed evolution, scientists reengineer biomolecules to find ones that perform beneficial new functions. The field is revolutionizing drug development, chemical engineering and other applications, but to realize its promise involves painstaking and time-consuming laboratory work.

9 Nov 2018

Small populations of normal T cells could modify disease severity in patients with XLP1

Human SH2D1A mutations resulting in X-linked lymphoproliferative syndrome type 1 are associated with a unique susceptibility to the Epstein-Barr virus, which may lead to fatal infectious mononucleosis.

9 Nov 2018

Young men struggle much more with body image disorders than thought

Young men who are overly preoccupied with building muscle have a significantly higher risk of depression, weekend binge drinking, and dieting that is not connected to obesity.

9 Nov 2018

Cells retain memory of chemical signals to which they are exposed

We all start out as a clump of identical cells. As these cells divide and multiply, they gradually take on distinct identities, acquiring the traits necessary to form, for instance, muscle tissue, bone, or nerves. A recent study from Rockefeller scientists offers new insight into how these cellular identities are cultivated over the course of development.

9 Nov 2018

New infrared detector may transform smartphones into pocket-sized portable labs

In its latest example of innovation performance, BASF has developed HertzstückTM, a groundbreaking infrared detector that may soon transform smartphones into pocket-sized portable laboratories. This new detector will enable consumers to use their phones to analyze food - for example, to measure the fat content of curd cheese, as shown in the infographic.

9 Nov 2018

Researchers develop powerful method to solve structures of small molecules

Small molecules -- from naturally occurring metabolites and hormones to synthetic medicines and pesticides -- can have big effects on living things. But for scientists to understand how the molecules work and how to design beneficial ones, they need to know the precise arrangement of atoms and chemical bonds.

9 Nov 2018

Salk researchers solve genetic 'whodunnit' for cancer gene

Long thought to suppress cancer by slowing cellular metabolism, the protein complex AMPK also seemed to help some tumors grow, confounding researchers. Now, Salk Institute researchers have solved the long-standing mystery around why AMPK can both hinder and help cancer.

8 Nov 2018

Researchers reveal link between autoimmune and cardiovascular disease in mice

People with autoimmune diseases such as psoriasis, lupus and rheumatoid arthritis are at high risk of developing cardiovascular disease, even though none of these conditions seem to target the cardiovascular system directly.

8 Nov 2018

Scientists move closer to gonorrhea vaccine after large-scale proteomic study

In a study of proteins historic in its scope, researchers at Oregon State University have pushed closer both to a vaccine for gonorrhea and toward understanding why the bacteria that cause the disease are so good at fending off antimicrobial drugs.

8 Nov 2018

Researchers identify epigenetic changes that increase risk of type 2 diabetes

Small chemical changes in the DNA building blocks, which may be influenceable by lifestyle factors, can reduce the amount of IGFBP2. A DIfE / DZD research team has now reported in the journal Diabetes that these epigenetic changes increase the risk of type 2 diabetes.

8 Nov 2018

GW study examines impact of nervous system on non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease, the accumulation of fat in the liver of people who drink little or no alcohol, affects 1 in 3 Americans. NAFLD is a significant risk factor for Type 2 diabetes, insulin resistance, and hepatic carcinoma, and incidence of the disease is increasing with the growing obesity epidemic in the United States.

8 Nov 2018

Circadian clock could play key role in the fight against liver cancer

The body's internal clock could play a critical role in the fight against certain types of liver cancer, according to a preclinical study by scientists from The University of Texas Health Science Center at Houston (UTHealth). The results were published recently in the journal Nature Communications.

8 Nov 2018