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Scientists describe novel conjugates made from antibodies and protein inhibitor

Linking therapeutically active molecules to specific antibodies can help to pilot them to their designated targets and minimize side effects--especially when treating tumors. In the journal Angewandte Chemie, scientists have now described novel conjugates made from antibodies and a kinesin spindle protein inhibitor.

31 Oct 2018

Scientists pinpoint TIM-3 protein as next potential target for immunotherapy treatments

Following the 2018 Nobel Prize for Medicine, global attention is now more than ever turned toward the promise of immunotherapy in oncology. An international team’s work has shed new light on a molecule called TIM-3 that might play a key role in the regulation of the immune response.

31 Oct 2018

World’s first vaccine against coeliac disease to be tested in Australia

US-based pharmaceutical company ImmusanT, after worldwide trials, is all set to start clinical trials of a new vaccine against coeliac disease at the Royal Melbourne Hospital Clinical Trials Centre in Melbourne. This will be followed by trials to be held at Adelaide, Brisbane, Perth, Mackay and Sunshine Coast say the sources.

31 Oct 2018

Researchers discover new, better marker to identify degree of brain damage after cardiac arrest

Last year, researchers Tobias Cronberg and Niklas Mattsson at Lund University in Sweden published a study showing serum tau levels to be a new and promising marker for identifying patients with severe brain damage after cardiac arrest.

31 Oct 2018

Researchers examine immune responses to CRISPR-Cas9 gene editing system

The CRISPR-Cas9 gene editing system has been generating excitement within the field of gene therapy, inspiring hopes of molecular tools capable of treating genetic diseases.

30 Oct 2018

New City of Hope CAR T cell trial focuses on HER2-positive breast cancer patients with brain metastases

Women with HER2-positive breast cancer that has spread to the brain need more treatment options, and City of Hope and Mustang Bio Inc. are meeting that challenge.

30 Oct 2018

Game-changing microscope enables UK scientists to understand amyloid structure

Scientists have used cryo-electron microscopes to generate 3D images of amyloid, showing that aggregates form long, twisted fibers.

30 Oct 2018

Cryo-electron microscopy helps study proteins responsible for amyloid-based diseases

The century old mission to understand how the proteins responsible for amyloid-based diseases such as Alzheimer's, Huntingdon's and Parkinson's work has taken major steps forward in the last 12 months, thanks to a revolution in a powerful microscopy technique used by scientists.

30 Oct 2018

Ten Allen Distinguished Investigators for 2018 announced by Paul G. Allen Frontiers Group

Nanoparticles that could reprogram a cancer patient's immune system inside their own body. Understanding a mysterious type of brain cell in the hopes of shedding new light on Alzheimer's disease. Reimagining nuclei, the DNA-storage compartments of our cells, as miniature lava lamps.

30 Oct 2018

Researchers use mRNA-loaded carriers to target genetic instructions of protein in immune cells

Delivering an effective therapeutic payload to specific target cells with few adverse effects is considered by many to be the holy grail of medical research. A new Tel Aviv University study explores a biological approach to directing nanocarriers loaded with protein "game changers" to specific cells.

30 Oct 2018

Scientists find ways to block nitration of amino acids to improve cancer immunotherapy

Immunotherapy -- harnessing T-cells to attack cancer cells in the body -- has given hope to patients who endure round after round of treatment, including chemotherapy, to little effect. For all of its promise, however, immunotherapy still benefits only a minority of patients -- a reality driving research in the field for ways to improve the relatively new approach.

30 Oct 2018

Cephalopods could become new source of protein for people around the world

Among chefs and researchers in gastronomy there is a growing interest in exploring local waters in order to use resources in a more diverse and sustainable manner, including using the cephalopod population as a counterweight to the dwindling fishing of bonefish, as well as an interest in finding new sources of protein that can replace meat from land animals.

30 Oct 2018

Scientists discover cell adhesion mechanism used by mycoplasma genitalium

Researchers from the Molecular Biology Institute of Barcelona and the Institute of Biotechnology and Biomedicine have discovered the mechanism by which the bacterium Mycoplasma genitalium) adheres to human cells.

29 Oct 2018

New findings highlight importance of inflammatory component in atherosclerosis pathogenesis

One of the main characteristics of atherosclerosis is the accumulation of lipids in the intimal layer of the arterial wall.

29 Oct 2018

Insights into tumor initiation pave way for new skin cancer treatments

Researchers from VIB and KU Leuven uncovered a key vulnerability of melanoma. While studying the role of the melanoma-specific long non-coding RNA SAMMSON in tumor initiation, the researchers found that it boosts protein synthesis in different cellular compartments. Normal cells are alerted by modification in protein synthesis and react to this threat, but only if this process is altered in one compartment at the time.

29 Oct 2018

Protein C News and Research

Scientists describe novel conjugates made from antibodies and protein inhibitor

Scientists pinpoint TIM-3 protein as next potential target for immunotherapy treatments

World’s first vaccine against coeliac disease to be tested in Australia

Researchers discover new, better marker to identify degree of brain damage after cardiac arrest

Researchers examine immune responses to CRISPR-Cas9 gene editing system

New City of Hope CAR T cell trial focuses on HER2-positive breast cancer patients with brain metastases

Game-changing microscope enables UK scientists to understand amyloid structure

Cryo-electron microscopy helps study proteins responsible for amyloid-based diseases

Ten Allen Distinguished Investigators for 2018 announced by Paul G. Allen Frontiers Group

Researchers use mRNA-loaded carriers to target genetic instructions of protein in immune cells

Scientists find ways to block nitration of amino acids to improve cancer immunotherapy

Cephalopods could become new source of protein for people around the world

Scientists discover cell adhesion mechanism used by mycoplasma genitalium

New findings highlight importance of inflammatory component in atherosclerosis pathogenesis

Insights into tumor initiation pave way for new skin cancer treatments

Study provides a new way of thinking about cold stress in plants

New method increases virus production in cells to generate more vectors for gene transfer

Scientists discover kill code in all cells that can be triggered to destroy cancer

Forced expression of a natural protein reduces fat in mice by a third

Natural protein may offer novel therapy to reverse disorders associated with metabolic syndrome

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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