Protein C News and Research

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Scientists create synthetic tissue capable of synchronized beating

A team of chemists at the University of Bristol have developed a prototissue that is capable of synchronized beating when it is heated and cooled.

16 Oct 2018

Study uncovers important role of PRMT1 in dilated cardiomyopathy

In a study published in iScience, Professor Akiyoshi Fukamizu of the Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (University of Tsukuba, JAPAN) and the research group reported a new work on discovery of the important role of PRMT1 in dilated cardiomyopathy.

16 Oct 2018

Zebrafish study uncovers molecular 'brake' that helps control eye lens development

How different cells in a multicellular organism acquire their identities remains a fundamental mystery of development. In the eye, for example, the lens contains two cell types - lens epithelial cells and lens fiber cells -- the first of which differentiates into the second as an animal matures.

16 Oct 2018

Rice University chemist wins big award to study small surfaces

It's one thing to start a chemical reaction and get a result, but it's quite another thing to watch it in progress. Rice University chemist Matt Jones wants to see it happen.

16 Oct 2018

Researchers develop fibrin-targeting immunotherapy to protect against neurodegeneration

Normally, the blood protein fibrin does not enter the brain. But in several neurological disorders, the blood-brain barrier--which keeps large molecules in the blood from entering the brain--becomes abnormally permeable, allowing fibrin to leak into the brain and trigger inflammation.

16 Oct 2018

Endurance exercise training beneficially alters gut microbiota composition

According to recent research, endurance exercise training beneficially modifies gut microbiota composition. After six weeks of training, potentially inflammation causing microbes (Proteobacteria) decreased and microbes that are linked to enhanced metabolism (Akkermansia) increased.

15 Oct 2018

Neuropsychiatric symptoms related to earliest stages of Alzheimer's brain pathology

UC San Francisco researchers, in collaboration with the unique Brazilian Biobank for Aging Studies at the University of São Paulo, have shown that the earliest stages of the brain degeneration associated with Alzheimer's disease are linked to neuropsychiatric symptoms including anxiety, depression, loss of appetite, and sleep disturbances.

15 Oct 2018

Modeling Non-Numerical Data in Systems Biology

An interview with Dr. Eshan Mitra, discussing the importance of computer models in biology and the development of a more accurate model of the RAF phosphorylation pathway.

15 Oct 2018

Scientists shed light on roles of transcription factors, TP63 and SOX2, in squamous cell carcinoma

Squamous cell carcinomas are aggressive malignancies arising from squamous epithelium of various organs, such as esophagus, head and neck, lung and skin. Previous studies demonstrated that two master transcription factors, TP63 and SOX2, effect genomic activation in SCCs.

15 Oct 2018

Study identifies molecular switch that controls fate of milk-producing breast cells

A research team, led by investigators from Georgetown Lombardi Comprehensive Cancer Center, details how a natural and dramatic process -- changes in mammary glands to accommodate breastfeeding -- uses a molecular process believed to contribute to survival of pre-malignant breast cells.

15 Oct 2018

Tobacco heating products cause less staining to teeth than conventional cigarettes

A study by scientists at British American Tobacco has shown that e-cigarettes and tobacco heating products cause significantly less staining to teeth than conventional cigarettes.

15 Oct 2018

First-of-its-kind study to test a personalized vaccine in cancer patient

Tamara Strauss has been living with high-grade, stage IV pancreatic neuroendocrine cancer for more than three years. Current treatments, although effective for her, are highly toxic.

15 Oct 2018

Study unravels how cancer stem cells use normal genes in abnormal ways

CDK1 is a "normal" protein - its presence drives cells through the cycle of replication. And MHC Class I molecules are "normal" as well - they present bits of proteins on the surfaces of cells for examination by the immune system.

15 Oct 2018

Researchers develop two-pronged approach for targeting Ebola virus

In a new study researchers have developed a two-pronged approach for targeting Ebola virus infection using linked nucleic acid (LNA) antisense oligonucleotides (ASOs)designed to interfere both genes essential for translation of Ebola virus genes and to block production of an intracellular human protein needed for the virus to enter cells.

12 Oct 2018

Study: Alterations in genes encoding proteins contribute to ADHD development

A team from I.M. Sechenov First Moscow State Medical University together with foreign colleagues analyzed the genomes of several families that have members with ADHD.

12 Oct 2018

Fat tissue could be a source of diabetes, shows new research

A new study by Australian researchers, out today, is challenging what we know about the causes of diabetes. The new research points to fat tissue as a source of disease, and widens our understanding beyond the traditional focus on liver and pancreas as the main culprits.

12 Oct 2018

Findings offer new insight into early changes that occur during AD pathology

Alzheimer's disease (AD) is the most common form of dementia, involving memory loss and a reduction in cognitive abilities.

12 Oct 2018

'Digital brain' recreates protein trafficking in the brain

Researchers have developed a digital 3D brain demonstrating how the toxic proteins involved in neurodegenerative diseases are transported through the brain.

12 Oct 2018

Antimicrobial signaling molecule has lower activity against hepatitis C virus in most humans

An antimicrobial signaling molecule called IFNλ4 has lower activity against the hepatitis C virus in the vast majority of humans compared with chimpanzees and African hunter-gatherer Pygmies, according to a study published October 11 in the open-access journal PLOS Pathogens by John McLauchlan’s research team at the MRC-University of Glasgow Centre for Virus Research in the UK, and colleagues.

12 Oct 2018

Study suggests new approach to treat life-threatening blood disorder in children

Pediatric researchers studying the life-threatening blood disorder Fanconi anemia have devised a method to block the abnormal biological signals that drive the disease.

12 Oct 2018

Protein C News and Research

Scientists create synthetic tissue capable of synchronized beating

Study uncovers important role of PRMT1 in dilated cardiomyopathy

Zebrafish study uncovers molecular 'brake' that helps control eye lens development

Rice University chemist wins big award to study small surfaces

Researchers develop fibrin-targeting immunotherapy to protect against neurodegeneration

Endurance exercise training beneficially alters gut microbiota composition

Neuropsychiatric symptoms related to earliest stages of Alzheimer's brain pathology

Modeling Non-Numerical Data in Systems Biology

Scientists shed light on roles of transcription factors, TP63 and SOX2, in squamous cell carcinoma

Study identifies molecular switch that controls fate of milk-producing breast cells

Tobacco heating products cause less staining to teeth than conventional cigarettes

First-of-its-kind study to test a personalized vaccine in cancer patient

Study unravels how cancer stem cells use normal genes in abnormal ways

Researchers develop two-pronged approach for targeting Ebola virus

Study: Alterations in genes encoding proteins contribute to ADHD development

Fat tissue could be a source of diabetes, shows new research

Findings offer new insight into early changes that occur during AD pathology

'Digital brain' recreates protein trafficking in the brain

Antimicrobial signaling molecule has lower activity against hepatitis C virus in most humans

Study suggests new approach to treat life-threatening blood disorder in children

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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