Biochemistry News and Research

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AI-driven automated system can help design biochemical pathways to produce lycopene

A new proof-of-concept study details how an automated system driven by artificial intelligence can design, build, test and learn complex biochemical pathways to efficiently produce lycopene, a red pigment found in tomatoes and commonly used as a food coloring, opening the door to a wide range of biosynthetic applications, researchers report.

13 Nov 2019

Tulane virus needs intracellular calcium to replicate

Some gastrointestinal viruses need calcium. They need calcium ions to carry out several essential aspects of viral life, such as entry into host cells, genome replication and building new viruses to invade other cells. The cells invaded by viruses also use calcium. They use it as signals to regulate many of the cells' own processes, but viruses can takeover cellular calcium signaling to satisfy their own needs.

13 Nov 2019

Scientists find driver for more deadly prostate cancer

A transcription factor that aids neuron function also appears to enable a cell conversion in the prostate gland that can make an already recurrent cancer even more deadly, scientists say.

13 Nov 2019

Contraceptive drug effective in preventing and regressing cervical cancer in mice

A new study in The American Journal of Pathology, published by Elsevier, reports that medroxyprogesterone acetate (MPA), the active ingredient in the common contraceptive injection Depo-Provera, was effective in preventing the development of cervical cancer in mice with precancerous lesions.

12 Nov 2019

Study provides new insight into antibiotic synthesis

Researchers at McGill University's Faculty of Medicine have made important strides in understanding the functioning of enzymes that play an integral role in the production of antibiotics and other therapeutics. Their findings are published in Science.

11 Nov 2019

Retinal hyperspectral imaging shows promise for early Alzheimer's disease detection

Alzheimer's disease is the leading cause of dementia in the U.S., with approximately 5.4 million currently affected and an estimated 16 million by 2050.

11 Nov 2019

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

For the first time, a study led by researchers at Helmholtz Zentrum München and the German Center for Diabetes Research shows how glucocorticoid hormones, such as cortisol, control sugar and fat levels differently during day and night, feeding and fasting, rest and activity, over the course of 24 hours.

10 Nov 2019

Study finds reliable biomarker for noninvasive detection of deadly infant disease

A diagnostic study of 136 premature infants found that a protein involved in managing harmful bacteria in the human intestine is a reliable biomarker for the noninvasive detection of necrotizing enterocolitis.

8 Nov 2019

UVA scientists develop a better way to determine what our genes do

Scientists at the University of Virginia School of Medicine have developed a better way to determine what our genes do – allowing scientists to better probe the genetic causes of diseases and more efficiently determine whether new drugs will act on the intended target exactly as needed.

7 Nov 2019

Cytoplasm of ruptured Xenopus frog eggs reorganizes into cell-like compartments, study shows

Can scrambled eggs unscramble themselves? Well, sort of.

6 Nov 2019

New bacteria-killing toxin shows promise to impact superbug infectious diseases

An international research collaboration has discovered a new bacteria-killing toxin that shows promise of impacting superbug infectious diseases.

6 Nov 2019

Inhibiting mutant CHIP protein activity could decrease severity of ataxia disease symptoms

For the first time, the UNC School of Medicine lab of Jonathan Schisler, MS, PhD, linked the specific biochemical changes to a protein called CHIP to specific disease characteristics of patients with a wide range of rare disorders.

6 Nov 2019

Scientists discover structure of novel RNA-modifying enzyme

RNA, or ribonucleic acid, is present in the cells of all living beings and required to synthesize proteins. A research team at the University of California, Riverside, has discovered the structure of a novel RNA-modifying enzyme, ZCCHC4, and identified the mechanism that controls how this enzyme recognizes its substrate.

6 Nov 2019

Study reveals key mechanism that helps cells to adapt to low-nutrient conditions

Scientists from the UNC School of Medicine and Stanford University have uncovered what may be a fundamental biological mechanism that helps organisms adapt to rapid changes to nutrients in their environments.

6 Nov 2019

New imaging methods provide unprecedented close-up view of cilia linked to blindness

A new study published today by researchers from Baylor College of Medicine and UT Health's McGovern Medical School in the Proceedings of the National Academy of Sciences reveals an unprecedented close-up view of cilia linked to blindness.

5 Nov 2019

The Achilles heel of APC-mutated colon tumors identified

In almost all cases of colon cancer, a specific gene is mutated – this offers opportunities to develop broadly effective therapeutic approaches. Research teams in Würzburg have taken this a step further.

5 Nov 2019

Humanizing cell cultures

Today we know the function and metabolism of any mammalian cell depends on its environment. Such cells have long been cultured under conditions consisting of a basal medium with added nutritional serum. This, however, is not an accurate replica of the cell’s environment within the human body.

5 Nov 2019

$Innovative technique aims to predict and reduce fractures in diabetics$

Biochemistry News and Research

AI-driven automated system can help design biochemical pathways to produce lycopene

Tulane virus needs intracellular calcium to replicate

Scientists find driver for more deadly prostate cancer

Contraceptive drug effective in preventing and regressing cervical cancer in mice

Study provides new insight into antibiotic synthesis

Retinal hyperspectral imaging shows promise for early Alzheimer's disease detection

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

Study finds reliable biomarker for noninvasive detection of deadly infant disease

UVA scientists develop a better way to determine what our genes do

Cytoplasm of ruptured Xenopus frog eggs reorganizes into cell-like compartments, study shows

New bacteria-killing toxin shows promise to impact superbug infectious diseases

Inhibiting mutant CHIP protein activity could decrease severity of ataxia disease symptoms

Scientists discover structure of novel RNA-modifying enzyme

Study reveals key mechanism that helps cells to adapt to low-nutrient conditions

New imaging methods provide unprecedented close-up view of cilia linked to blindness

The Achilles heel of APC-mutated colon tumors identified

Humanizing cell cultures

Innovative technique aims to predict and reduce fractures in diabetics

New technique uses light to control lifetime of protein inside the cell

Researchers make major breakthrough in cell signalling

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