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New therapy may help treat or prevent multiple sclerosis

Multiple sclerosis, an autoimmune disease of the central nervous system that affects millions worldwide, can cause debilitating symptoms for those who suffer from it.

13 Oct 2020

Research shows 10 or more medications are prescribed to older heart failure patients

More than half of older patients hospitalized for heart failure, a progressive condition in which the heart doesn't pump blood as well as it should, are discharged from the hospital with prescriptions for 10 or more medications, according to new research published today in Circulation: Heart Failure, an American Heart Association journal.

13 Oct 2020

Molecular stilts help deadly parasites to invade host cells

In biological terms, gliding refers to the type of movement during which a cell moves along a surface without changing its shape. This form of movement is unique to parasites from the phylum Apicomplexa, such as Plasmodium and Toxoplasma.

13 Oct 2020

Cell-free DNA blood tests may help predict pregnancy complications

UCLA researchers say a blood test commonly used to detect fetal genetic abnormalities may help predict complications associated with pregnancy before symptoms develop.

13 Oct 2020

Researchers launch new clinical trial to investigate role of vitamin D against COVID-19

Researchers from Queen Mary University of London, funded by Barts Charity, have launched a new clinical trial to investigate whether taking vitamin D could protect people from COVID-19

13 Oct 2020

Researchers explore molecular factors that drive the severity of COVID-19

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months.

13 Oct 2020

In vitro BA-LRA can help detect small molecule drugs for drug-induced liver injury

BioIVT, a leading provider of research models and services for drug and diagnostic development, today announced the publication of research describing the use of HEPATOPAC® cultures with a targeted in vitro assay to identify small molecule drugs with high potential for drug-induced liver injury (DILI).

13 Oct 2020

Even light physical activity can significantly boost health, shows study

More than 5 million people around the world die from causes associated with a lack of physical activity. Two research teams at UC San Diego School of Medicine sought to understand sedentary lifestyles, with one study finding that even light physical activity, including just standing, can benefit health, and the other that Americans are still sitting too much.

13 Oct 2020

Researchers call for nutritional guidelines and regulations on use of vitamin D

The professional perception of vitamin D as a medicine, rather than as a key nutrient, is constraining practice and jeopardizing the health of elderly care home residents in England, conclude researchers in the journal BMJ Nutrition Prevention & Health.

13 Oct 2020

New study details how Michigan nursing homes limited the spread of coronavirus

Seven months ago, the nation first heard of a surge of COVID-19 deaths in a Washington nursing home – an early warning sign of how the coronavirus could rip through such facilities.

13 Oct 2020

COVID-19 vaccine candidate shows potent immune response

A COVID-19 vaccine candidate that underwent extensive preclinical testing at the University of Alabama at Birmingham this spring and summer shows potent preclinical immune responses - including several that distinguish it from other COVID-19 vaccine approaches - according to a preprint deposited in the BioRxiv repository this week.

13 Oct 2020

Female mosquitoes can detect a combination of four different substances in blood

Mosquitoes spread diseases like malaria, dengue, and yellow fever that kill at least a half a million people each year. Now researchers are learning what humans taste like to mosquitoes, down to the individual neurons that sense blood's distinctive, delectable flavor.

13 Oct 2020

Neoadjuvant trial of combination immunotherapy has favorable outcomes in bladder cancer patients

Neoadjuvant, or pre-surgical, combination treatment with the immune checkpoint inhibitors tremelimumab (anti-CTLA-4) and durvalumab (anti-PD-1) was well-tolerated and showed early signs of activity in certain patients with localized bladder cancer who do not have standard treatment options available, according to a Phase I clinical trial conducted by The University of Texas MD Anderson Cancer Center.

13 Oct 2020

Scientists explain why some COVID-19 patients develop neurological symptoms

Now, a new study published on the preprint server bioRxiv sheds light on the mechanism behind brain involvement in the COVID-19 pandemic. A team of researchers at the Krembil Research Institute and the University of Toronto in Canada aimed to understand further the potential mechanisms underlying SARS-CoV-2 tropism for brain vasculature to see how infection occurs in the brain.

13 Oct 2020