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New method could help understand functions of gut microbiome

Researchers at Harvard Medical School and Columbia University in the United States have developed a way to study the functions of hard-to-grow bacteria that contribute to the composition of the gut microbiome. The new method is published in the journal Molecular Systems Biology.

12 Mar 2015

TSRI researchers create picture of whole dynein-dynactin structure

A team led by scientists at The Scripps Research Institute has determined the basic structural organization of a molecular motor that hauls cargoes and performs other critical functions within cells.

12 Mar 2015

Understanding strengths and weaknesses of hepatitis C viruses

Using a specially selected library of different hepatitis C viruses, a team of researchers led by Johns Hopkins scientists has identified tiny differences in the pathogens' outer shell proteins that underpin their resistance to antibodies.

12 Mar 2015

Researchers take important step in repairing the cerebral cortex of adult mouse

A team led by Afsaneh Gaillard (Inserm Unit 1084, Experimental and Clinical Neurosciences Laboratory, University of Poitiers), in collaboration with the Institute of Interdisciplinary Research in Human and Molecular Biology (IRIBHM) in Brussels, has just taken an important step in the area of cell therapy: repairing the cerebral cortex of the adult mouse using a graft of cortical neurons derived from embryonic stem cells.

12 Mar 2015

Simple blood test could be developed to diagnose Alzheimer's disease, say UCLA researchers

UCLA researchers have provided the first evidence that a simple blood test could be developed to confirm the presence of beta amyloid proteins in the brain, which is a hallmark of Alzheimer's disease.

12 Mar 2015

CHOP researchers find link between infancy BMI and childhood obesity

Body mass index (BMI) during infancy may help to predict if a child will be obese by age four. In a study focused on the infant BMI-childhood obesity relationship in a cohort with a majority of African-American children, researchers from The Children's Hospital of Philadelphia say that a better understanding of infant growth patterns may lead to more effective early efforts at obesity prevention.

12 Mar 2015

Glucocorticoid therapies promote functional recovery of blood-brain barrier after blast injury

Barclay Morrison III, associate professor of biomedical engineering at Columbia Engineering, has led the first study to determine underlying biological mechanisms that promote functional recovery of the blood-brain barrier (BBB) after blast injury. The research demonstrates that treatment with the glucocorticoid, dexamethasone, after primary blast injury promotes rapid recovery of an in vitro model of the BBB, a highly restrictive semi-permeable barrier whose primary function is to maintain the brain's microenvironment and protect it from potentially toxic substances.

12 Mar 2015

Weak spots in ebola’s defenses: an interview with Dr. Andrew Ward

There are hundreds of other antibodies against Ebola that we are in the process of imaging using the electron microscope. We are looking for new sites of vulnerability as well as subtle differences in the way the known sites are attacked. In particular we are looking for antibodies that the virus is unlikely to escape from when it mutates.

11 Mar 2015

Understanding the role of next generation sequencing in stratified cancer medicine

Oxford Gene Technology, The Molecular Genetics Company, has teamed up with clinical research experts in a new article available online, discussing the role of next generation sequencing (NGS) in cancer medicine.

From Oxford Gene Technology 11 Mar 2015

Advanced clinical decision support tools reduce mortality for pneumonia patients

A new study by Intermountain Medical Center researchers in Salt Lake City found that using advanced clinical decision support tools reduces mortality for the 1.1 million patients in the Unites States who are treated for pneumonia each year.

11 Mar 2015

Insomnia symptoms affect suicide risk among people who drink alcohol

Insomnia symptoms affect the risk of suicide among people who drink alcohol, according to a groundbreaking study led by the director of Mississippi State University's Sleep, Suicide and Aging Laboratory.

11 Mar 2015

LSDF announces new Matching grants to promote treatments for devastating medical conditions

The Life Sciences Discovery Fund today announced nearly $1 million in Matching grants to two Washington-based companies to promote translation of promising treatments for devastating medical conditions from the laboratory to the commercial marketplace.

11 Mar 2015

Berkeley Lab scientists uncover new clues about cancer risk from low-dose radiation

Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory have uncovered new clues about the risk of cancer from low-dose radiation, which in this research they define as equivalent to 100 millisieverts or roughly the dose received from ten full-body CT scans.

11 Mar 2015

Quest Diagnostics to provide whole exome sequencing service to diagnose neurological disorders

Quest Diagnostics, the world's leading provider of diagnostic information services, today announced the availability of Neurome, a whole exome sequencing service designed to aid the diagnosis of rare neurological disorders in pediatric populations.

From Quest Diagnostics 10 Mar 2015

Varian Medical Systems plans to expand operations in Fulton County, Georgia

Varian Medical Systems, the world's leading manufacturer of medical devices and software for treating cancer as well as a premier supplier of X-ray imaging components, today announced that it will expand its operations in Fulton County, Georgia. Company officials anticipate that this expansion will enable it to better serve its East Coast customers and accommodate anticipated growth that will create up to 100 new high-paying technical jobs over the next five years.

10 Mar 2015

Salk scientists move one step closer to creating drug that could prevent HIV virus

Imagine a single drug that could prevent human immunodeficiency virus (HIV) infection, treat patients who have already contracted HIV, and even remove all the dormant copies of the virus from those with the more advanced disease. It sounds like science fiction, but Salk scientists have gotten one step closer to creating such a drug by customizing a powerful defense system used by many bacteria and training this scissor-like machinery to recognize the HIV virus.

10 Mar 2015

Study shows that households can serve as reservoir for transmitting MRSA

Households can serve as a reservoir for transmitting methicillin-resistant Staphylococcus aureus (MRSA), according to a study published this week in mBio, the online open-access journal of the American Society for Microbiology. Once the bacteria enters a home, it can linger for years, spreading from person to person and evolving genetically to become unique to that household.

10 Mar 2015

Narcolepsy bears trademarks of classic autoimmune disorder

Narcoleptics suffer from bouts of sleepiness and sleep attacks, which impair their ability to function in daily life. But the precise cause of narcolepsy has long eluded scientists, and the cure for the devastating neurological disorder afflicting an estimated three million people worldwide -- and one in 3,000 Americans -- remains at bay.

10 Mar 2015

Imperial scientists develop new test that uses human stem cells to predict side effects of drugs

Scientists at Imperial College London have developed a test that uses combinations of cells from a single donor's blood to predict whether a new drug will cause a severe immune reaction in humans.

10 Mar 2015

Researchers take images of tiny molecular machine that bacteria use to infect host cells

Armed with a microscope capable of zooming in on organisms measured in billionths of a meter, scientists report they are the first to observe one of the tiny molecular machines that bacteria use to infect host cells. Findings appear in the Proceedings of the National Academy of Sciences.

10 Mar 2015

Laboratory News and Research

New method could help understand functions of gut microbiome

TSRI researchers create picture of whole dynein-dynactin structure

Understanding strengths and weaknesses of hepatitis C viruses

Researchers take important step in repairing the cerebral cortex of adult mouse

Simple blood test could be developed to diagnose Alzheimer's disease, say UCLA researchers

CHOP researchers find link between infancy BMI and childhood obesity

Glucocorticoid therapies promote functional recovery of blood-brain barrier after blast injury

Weak spots in ebola’s defenses: an interview with Dr. Andrew Ward

Understanding the role of next generation sequencing in stratified cancer medicine

Advanced clinical decision support tools reduce mortality for pneumonia patients

Insomnia symptoms affect suicide risk among people who drink alcohol

LSDF announces new Matching grants to promote treatments for devastating medical conditions

Berkeley Lab scientists uncover new clues about cancer risk from low-dose radiation

Quest Diagnostics to provide whole exome sequencing service to diagnose neurological disorders

Varian Medical Systems plans to expand operations in Fulton County, Georgia

Salk scientists move one step closer to creating drug that could prevent HIV virus

Study shows that households can serve as reservoir for transmitting MRSA

Narcolepsy bears trademarks of classic autoimmune disorder

Imperial scientists develop new test that uses human stem cells to predict side effects of drugs

Researchers take images of tiny molecular machine that bacteria use to infect host cells

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