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The obesity epidemic - does the evidence stack up?

Last week, the UK health secretary declared that we are in a grip of an obesity epidemic, but does the evidence stack up? Researchers in this week's BMJ debate the issue.

5 Feb 2008

Black people die more frequently of severe sepsis that either whites or Hispanics

Blacks have almost double the rate of severe sepsis an overwhelming infection of the bloodstream accompanied by acute organ dysfunction as whites, according to recent research.

5 Feb 2008

Risk factors for severe RSV infection in immunocompromised children

St. Jude Children's Research Hospital investigators and collaborators have shown how to predict if a child who is infected with respiratory syncytial virus (RSV) while being treated for cancer or another catastrophic disease is at high risk for developing severe infection. The finding will help clinicians improve guidelines for managing these infected children.

4 Feb 2008

New discoveries on what does and doesn't affect immune system

Scientists know that a number of factors can affect the body's immune system: poor diet, certain steroids, chronic stress. Now researchers at Michigan State University have discovered that an appetite-controlling hormone also affects the immune system, while natural versions of certain steroids do not.

4 Feb 2008

Intensive insulin therapy reduces the risk of death in critically ill patients

For critically ill patients, intensive insulin therapy (IIT) to keep blood sugar (glucose) at normal levels reduces the risk of acute kidney injury, reports a study in the March Journal of the American Society of Nephrology.

4 Feb 2008

Best way to treat abdominal aortic aneurysms

Abdominal aortic aneurysm (AAA) - a condition in which the large vessel that supplies blood to your abdomen, legs, and pelvis swells to over 50 percent its normal size -occurs in approximately 4 out of 100 adults.

4 Feb 2008

March of Dimes works to eliminate racial gaps in infant health

In recognition of Black History Month, the March of Dimes is drawing attention to the tremendous gap in premature birth and infant mortality rates that disproportionately affect black women in the United States and to the programs and research designed to reduce -- and one day eliminate -- these disparities.

4 Feb 2008

Why is scratching so nice?

In the first study to use imaging technology to see what goes on in the brain when we scratch, researchers at Wake Forest University Baptist Medical Center have uncovered new clues about why scratching may be so relieving - and why it can be hard to stop. The work is reported online in the Journal of Investigative Dermatology and will appear in a future print issue.

31 Jan 2008

Severe asthma may be a different form of the disease

A multi-center research project to investigate severe asthma has found a key physiological difference between severe and non-severe forms of the disease, a finding that could help explain why those with severe asthma do not respond well to treatment.

31 Jan 2008

Heart transplant standards set too low

Heart surgeons at Johns Hopkins have evidence to support further tightening rather than easing of standards used to designate hospitals that are best at performing heart transplants.

30 Jan 2008

Link between microRNA expression patterns and poor outcomes for colon cancer

Preliminary research has found an association between certain microRNA expression patterns and poor survival and treatment outcomes for colon cancer, according to a study in the January 30 issue of JAMA: The Journal of the American Medical Association.

30 Jan 2008

Malnourishment in young mothers and their babies has consequences well beyond infant health and mortality

Maternal and child under-nutrition have a life-long impact on the health and prospects of the child, potentially affecting future generations.

28 Jan 2008

Heart and stroke death rates steadily decline; risks still too high

In an appropriate prelude to American Heart Month, which is just ahead in February, new mortality data from the Centers for Disease Control and Prevention (CDC) shows that, since 1999, coronary heart disease and stroke age-adjusted death rates are down by 25.8 percent and 24.4 percent, respectively.

23 Jan 2008

Risk of death cut in half with 30 minutes of exercise in men

Increased exercise capacity reduces the risk of death in African-American and Caucasian men, researchers reported in Circulation: Journal of the American Heart Association.

23 Jan 2008

Treatment with hormone suppression therapy and radiation improves survival for certain prostate cancer patients

Men with localized prostate cancer who were treated with male hormone suppression therapy and radiation treatment had longer survival, but those with moderate to high levels of other illnesses did not experience this effect, according to a study in the January 23 issue of JAMA: The Journal of the American Medical Association.

23 Jan 2008

Study looks at off-label use of biliary stents

Although approved by the U.S. Food and Drug Administration as a palliative treatment for cancer patients who have developed bile-duct obstructions, biliary stents are sometimes used "off-label" for the treatment of peripheral vascular disease (PVD).

22 Jan 2008

Change in trauma level designation associated with improved patient survival

Death rates among patients admitted to a Colorado trauma center appeared to decrease after the center's designation was upgraded, according to a report in the January issue of Archives of Surgery, one of the JAMA/Archives journals.

22 Jan 2008

Something special about loneliness

New research at the University of Chicago finds evidence for a clever way that people manage to alleviate the pain of loneliness: They create people in their surroundings to keep them company.

21 Jan 2008

British health service blamed for 17,000 unnecessary deaths each year

Campaigners in Britain say the National Health Service (NHS) is responsible for 17,000 unnecessary deaths each year because of poor performance.

20 Jan 2008

Previously unknown Merkel cell polyomavirus linked to deadly skin cancer

A new strategy to hunt for human viruses described in this week's issue of the journal Science by the husband-and-wife team who found the cause of Kaposi's sarcoma has revealed a previously unknown virus strongly associated with another rare but deadly skin cancer called Merkel cell carcinoma.

18 Jan 2008