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Protein that causes juvenile Batten disease also plays a key role in normal cell function

The aberrant protein that causes juvenile Batten disease, a fatal neurodegenerative disorder of childhood, also plays a key role in normal cell function, Duke University Medical Center researchers have found.

16 Sep 2004

Researchers are making inroads to understanding what makes brain tumors so hard to treat

When he's not in the operating room performing surgery, Donald M. O'Rourke, M.D., Associate Professor of Neurosurgery at the University of Pennsylvania School of Medicine is fighting brain tumors from the research laboratory bench.

16 Sep 2004

Researchers get a grip on marijuana

Now researchers at Stanford University School of Medicine are a step closer to understanding how the drug's active ingredients - tetrahydrocannabinol and related compounds, called cannabinoids - may exert their effects.

16 Sep 2004

Disruption of protein folding causes neurodegeneration, mental retardation

Excess accumulation in brain cells of a fat molecule called GM1-ganglioside (GM1) disrupts the folding of newly assembled proteins into their proper shapes, triggering nerve degeneration and mental retardation in children.

10 Sep 2004

Pig tissue may help reduce the damage and disability of stroke

A tiny capsule containing tissue that secretes a cocktail of brain-nourishing neurotrophic factors may one day help reduce the damage and disability of stroke, according to research published in the September issue of Stroke.

7 Sep 2004

First Parkinson’s gene therapy patient well after 1 year suggesting that the therapy is safe and effective

The first ever patient to have undergone gene therapy for Parkinson’s appears to have come through phase I without a hitch, suggesting that the therapy is safe and effective, reports Marina Murphy in Chemistry & Industry.

2 Sep 2004

Hormone leptin could play a key role in treating bone loss, anorexia and infertility in women

A new study has found that the hormone leptin plays a key role in women’s reproductive and neuroendocrine health and suggests a future for the hormone in treating a number of conditions including exercise-induced bone loss, anorexia and in some cases of infertility.

2 Sep 2004

Alcohol in moderation maintains a healthy heart and reduces tissue damage following a heart attack

For years researchers have tried to determine why the French have such a lower rate of cardiovascular disease, given the amount of fat consumed in their diets.

30 Aug 2004

Further evidence of a genetic link to schizophrenia

Mice with specific genetic mutations exhibit behavior similar to human psychosis, report UT Southwestern Medical Center at Dallas researchers, providing further support to the notion of a genetic link to schizophrenia.

30 Aug 2004

Gray matter in brain associated with language processing among people with a family history of dyslexia

Italian researchers have observed significant reductions of gray matter volume in areas of the brain associated with language processing among people with a family history of dyslexia in comparison with controls with no reading problems.

24 Aug 2004

Stem cell research may one day help cerebral palsy

Natural chemicals that assist healing may one day help transplanted adult stem cells integrate into an injured brain, helping children with cerebral palsy recover lost function, according to researchers at the Medical College of Georgia.

18 Aug 2004

Newly discovered protein switch may be key to understanding sleep disorders, anxiety, and depression

University of California researchers have found that a newly discovered protein switch which they named neuropeptide S appears to work in the brain to enhance wakefulness and reduce anxiety in laboratory animals. According to Rainer Reinscheid and his colleagues, the protein could help in the understanding of sleep disorders, anxiety, and depression.

18 Aug 2004

The prion appears to function as an evolutionary stepping stone

“This prion,” explains Lindquist, “has a capacity to hide and release genetic information throughout the entire genome that can contribute to new traits in a complex way.”

16 Aug 2004

Study on RNAi technology targeting neurodegenerative diseases

Sirna Therapeutics has announced the publication of preclinical studies evaluating RNA interference-based therapies for a class of inherited neurodegenerative diseases of the central nervous system (CNS) in the current issue of Nature Medicine.

16 Aug 2004

Relationship between brain chemical messenger glutamate and schizophrenia traits

Researchers at the NIH's National Institute of Mental Health (NIMH) have identified a relationship between a small section of one gene, the brain chemical messenger glutamate, and a collection of traits known to be associated with schizophrenia.

15 Aug 2004

Gene responsible for management of glutamate is a promising candidate in determining risk for schizophrenia

Researchers at the National Institute of Mental Health have identified a relationship between a small section of one gene, the brain chemical messenger glutamate, and a collection of traits known to be associated with schizophrenia.

11 Aug 2004

Alzheimer’s sufferers are more likely to have jobs that are less mentally challenging than people without Alzheimer’s disease

Alzheimer's is a progressive form of presenile dementia that is similar to senile dementia except that it usually starts in the 40s or 50s; first symptoms are impaired memory which is followed by impaired thought and speech and finally complete helplessness

9 Aug 2004

Smart drug that targets cancer cells in the brain following removal of a tumor

The use of a "smart" drug that targets cancer cells in the brain following removal of a tumor may provide treatment that can extend the survival of people with the most common form of primary malignant brain tumor, glioblastoma multiforme (GBM).

3 Aug 2004

New gene therapy treatment involves injecting Herpes simplex virus into the brain tumours of Glioma patients

Experts on the Gene Therapy Advisory Committee have given the go ahead for a large clinical trial of a new treatment for patients with Glioma - one of the most aggressive types of brain tumours for which there is currently no cure.

3 Aug 2004

Researchers have shown that an experimental vaccine can reduce the amount of neurodegeneration in a mouse model for Parkinson's disease

The finding suggests that a similar therapy might eventually be able to slow the devastating course of Parkinson's disease in humans.

29 Jul 2004

Brain Cell News and Research

Protein that causes juvenile Batten disease also plays a key role in normal cell function

Researchers are making inroads to understanding what makes brain tumors so hard to treat

Researchers get a grip on marijuana

Disruption of protein folding causes neurodegeneration, mental retardation

Pig tissue may help reduce the damage and disability of stroke

First Parkinson’s gene therapy patient well after 1 year suggesting that the therapy is safe and effective

Hormone leptin could play a key role in treating bone loss, anorexia and infertility in women

Alcohol in moderation maintains a healthy heart and reduces tissue damage following a heart attack

Further evidence of a genetic link to schizophrenia

Gray matter in brain associated with language processing among people with a family history of dyslexia

Stem cell research may one day help cerebral palsy

Newly discovered protein switch may be key to understanding sleep disorders, anxiety, and depression

The prion appears to function as an evolutionary stepping stone

Study on RNAi technology targeting neurodegenerative diseases

Relationship between brain chemical messenger glutamate and schizophrenia traits

Gene responsible for management of glutamate is a promising candidate in determining risk for schizophrenia

Alzheimer’s sufferers are more likely to have jobs that are less mentally challenging than people without Alzheimer’s disease

Smart drug that targets cancer cells in the brain following removal of a tumor

New gene therapy treatment involves injecting Herpes simplex virus into the brain tumours of Glioma patients

Researchers have shown that an experimental vaccine can reduce the amount of neurodegeneration in a mouse model for Parkinson's disease

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