Myocardial Infarction News and Research

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Genentech announces positive outcomes from Lucentis Phase III trial against DME

Genentech, a member of the Roche Group, today announced that two-year results from a pivotal Phase III trial showed patients with diabetic macular edema who received Lucentis experienced rapid and sustained improvement in vision compared to those who received a placebo injection.

11 Mar 2011

Increased alcohol consumption leads to multiple cardiovascular outcomes

A summary paper on the effects of alcohol consumption on biologic mechanisms associated with coronary heart disease provides an excellent review of a large number of intervention studies in humans.

8 Mar 2011

Researchers identify 13 new gene sites linked with risk of coronary artery disease

An international research collaboration has identified 13 new gene sites associated with the risk of coronary artery disease and validated 10 sites found in previous studies. Several of the novel sites discovered in the study, which is being published online in Nature Genetics, do not appear to relate to known risk factors, suggesting previously unsuspected mechanisms for cardiovascular disease.

6 Mar 2011

Geron's hESC derived GRNCM1 halts remodeling process and preserves cardiac function in acute heart damage

Geron Corporation today announced preclinical study data showing positive effects of GRNCM1, Geron's cardiomyocyte product derived from human embryonic stem cells (hESCs), in a small animal model of acute heart damage. Administering GRNCM1 by injection into the heart resulted in greater resistance to induced arrhythmias, halted adverse cardiac remodeling and preserved mechanical function compared to controls.

2 Mar 2011

New cell therapy can reverse effect of 'bad' LDL cholesterol and reduce atherosclerosis

Researchers at the Swedish medical university Karolinska Institutet have shown in a new study on mice, that cell therapy can be used to reverse the effect of 'bad' LDL cholesterol and reduce the inflammation that leads to atherosclerosis.

1 Mar 2011

Scientists fuse human fat stem cells with rat cardiomyocytes to form new muscles

If Dr. Doolittle is famous for talking to animals, then here's a story that might make him hold his tongue: According to new research published online in The FASEB Journal, scientists have successfully fused human stem cells derived from subcutaneous adipose tissue with muscle cells from rat hearts.

1 Mar 2011

Dizziness, nausea and achiness are symptoms of heart attack in females

Dizziness, nausea and achiness – no, these are not symptoms of the flu but signs of a heart attack in females. While heart attacks affect both men and women, the symptoms of a heart attack are surprisingly different between the genders. Virginia Health Information (VHI) this week released its Cardiac Care Report which provides consumers information comparing heart healthcare in Virginia. This year's report reveals women undergoing open heart surgery continued a five year trend of higher than expected readmission rates.

25 Feb 2011

Omega-3 fish oils: Natural health solution for the heart

Did you know that over the average life span, a heart beats 2 to 3 billion times? As one of the hardest working muscles pumping oxygen and essential nutrients throughout your body an average of 100,000 times a day, the heart needs a lot of help to stay working fit.

25 Feb 2011

Human umbilical cord blood-derived EPCs accelerate wound healing in diabetics

Transplanting human umbilical cord blood-derived endothelial progenitor cells (EPCs) has been found to "significantly accelerate" wound closure in diabetic mouse models, said a team of Korean researchers publishing in the current issue of Cell Transplantation.

23 Feb 2011

Study: Gender may not increase risk of heart attack deaths

A study led by the University of Michigan Cardiovascular Center shows being a woman may not increase your risk of dying from treatment for a severe heart attack.

21 Feb 2011

Medtronic: Kyphon Balloon Kyphoplasty provides better back pain relief in cancer patients

Medtronic Inc., today announced the results of the first randomized, controlled trial comparing Kyphon Balloon Kyphoplasty with non-surgical care in treating spinal fractures in cancer patients. The study found that Kyphon Balloon Kyphoplasty provided cancer patients better back-specific function, more rapid back pain relief and improved quality of life compared with non-surgical care one month after treatment.

17 Feb 2011

Avesthagen completes development of microalgae based vegetarian DHA omega 3 essential fatty acid

Avesthagen Limited announced completion of a landmark project for the development of AvestaDHA(TM) - a vegetarian source of DHA (docohexanoic acid) omega 3 essential fatty acid based on an innovative approach using naturally occurring microalgae.

17 Feb 2011

Racial disparities in readmissions related to both patient race and site of care

Elderly Medicare black patients have a higher 30-day hospital readmission rate for several conditions including congestive heart failure and pneumonia compared to white patients, that is related in part to higher readmission rates among hospitals that disproportionately care for black patients, according to a study in the February 16 issue of JAMA.

16 Feb 2011

UCLA study finds stroke, cardiovascular disease have exacted enormous toll on Hollywood stars

A study by researchers at the UCLA Stroke Center found that stroke and cardiovascular disease have exacted an enormous toll on Hollywood stars.

14 Feb 2011

Scientists develop novel approach to detect long-distance chromosomal interactions for CAD

The discovery that a "gene desert" on chromosome 9 was a hotspot for coronary artery disease (CAD) risk was among the highlights of findings produced recently by genome-wide association studies, which compare the genomes of many people for genetic variations and have been broadly used in the past few years to study hundreds of diseases and complex traits. Gene deserts are large genomic segments devoid of genes.

10 Feb 2011

Research roundup: Comparing profit and nonprofit hospice care; Hospital mortality and spending; High-deductible insurance plans

Association Of Hospice Agency Profit Status With Patient Diagnosis, Location of Care, and Length of Stay - "The current Medicare Hospice Benefit reimburses hospices at a fixed per diem rate that does not consider the patient's diagnosis, location of care, or hospice LOS [length-of-stay]," and as such, "profit can be maximized by caring for patients with certain diagnoses that require fewer skilled services, patients residing in nursing homes, or patients with longer hospice stays."

4 Feb 2011

UofL receives $9.56 million NIH/NHLBI grant to study cardioprotective therapies

The National Heart, Lung and Blood Institute has awarded $9.56 million over five years to a University of Louisville Health Sciences Center research scientist to form a multi-center network examining cardioprotective therapies at the preclinical level.

4 Feb 2011

NIH awards multi-million dollar grant to form four-center cardiovascular research network

The National Heart, Lung and Blood Institute has awarded a multi-million dollar grant to Dr. Roberto Bolli of the University of Louisville to form a four-center network examining cardioprotective therapies at the preclinical level.

2 Feb 2011

Nitrous oxide anesthesia may lead to increased risk of myocardial infarction: Study

Patients receiving nitrous oxide as part of general anesthesia for surgery may be at increased long-term risk of myocardial infarction (heart attack), reports a study in the February issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

29 Jan 2011

NQF endorses outcome measures to improve quality of care for people with mental illnesses

The National Quality Forum has endorsed outcome measures to assess the results and thereby improve the quality of care provided to people with mental illnesses. The 4 endorsed mental health measures focus on depression and patients' satisfaction during an inpatient psychiatric hospital stay.

27 Jan 2011