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BioIVT announces research into mechanisms involved in cholestatic drug-induced liver injury

BioIVT, a leading provider of research models and services for drug development, today announced its research into the mechanisms involved in cholestatic drug-induced liver injury has been published in Applied In Vitro Toxicology.

10 Sep 2018

Novel finding that links ALS/ataxia to cellular stress opens door to new treatment approaches

Few treatments exist for neurodegenerative diseases that progressively rob a person's ability to move and think, yet the results of a new study could potentially open additional approaches for exploration.

7 Sep 2018

Family genetic background essential for understanding autism progression

Whether an individual develops a neurodevelopmental disorder like autism or ADHD and the severity of that disorder depends on genetic changes beyond a single supposedly disease-causing mutation.

7 Sep 2018

Chemical signals influence guest-host protocell interactions

Resident artificial cells shown to leave their protocell hosts when triggered by a chemical signal that causes them to behave antagonistically.

7 Sep 2018

Daytime sleepiness found to be a potential risk factor for Alzheimer’s disease

Older adults who frequently report feeling sleepy during the day are three times more likely to develop Alzheimer's in later life, according to a new study.

7 Sep 2018

Hsp90 protein appears to stimulate exosome release

Researchers from the Verstreken lab have identified a completely novel function for Hsp90, one of the most common and most studied proteins in our body.

7 Sep 2018

Scientists discover key aspect in the development of multiple sclerosis

In multiple sclerosis, not only the T cells of the immune system, but also its B cells, play an important role.

7 Sep 2018

Exeter’s new system can probe microscopic environments inside cells

A new system capable of probing microscopic environments inside cells has been installed at the University of Exeter's Bioimaging Centre.

7 Sep 2018

Study: Health and longevity improves with increased fasting time

Increasing time between meals made male mice healthier overall and live longer compared to mice who ate more frequently, according to a new study published in the Sept. 6, 2018 issue of Cell Metabolism.

7 Sep 2018

New study aims to understand why skin grafts have high rate of rejection

When it comes to transplant rejection, some organs are far trickier than others. Some transplantable organs, such as the liver, are readily accepted by the recipient's immune system, rarely triggering an immune response and rejection

7 Sep 2018

Research team identifies new therapeutic target for castration-resistant prostate cancer

A collaborative research team has linked the development of castration-resistant prostate cancer and resistance to treatment to a lack of androgen receptor expression in prostate cancer cells, identifying a new therapeutic target for one of the deadliest forms of cancer among men.

7 Sep 2018

Ground-breaking therapeutic process can destroy bowel cancer cells

Researchers at Queen's University Belfast have discovered a ground-breaking therapeutic process that can target and kill bowel cancer cells, which may improve survival rates for bowel cancer patients globally.

6 Sep 2018

Research uncovers how the immune system detects DNA damage

Our immune system is working every day to protect us from bacteria, viruses, and parasites, but it can also detect when our own cells are damaged.

6 Sep 2018

Natural plant compound exploits newly identified Achilles' heel in uveal melanoma

A natural plant compound exploits a newly identified Achilles' heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma cell growth, according to researchers at Washington University School of Medicine in St. Louis.

6 Sep 2018

Verastem doses first patient in Phase I/II clinical trial of duvelisib in combination with venetoclax

Verastem, Inc., operating as Verastem Oncology, a biopharmaceutical company focused on developing and commercializing medicines to improve the survival and quality of life of cancer patients, today announced dosing of the first patient in a multicenter Phase I/II clinical trial at the Dana-Farber/Harvard Cancer Center of duvelisib in combination with venetoclax in patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.

6 Sep 2018

Protein C News and Research

BioIVT announces research into mechanisms involved in cholestatic drug-induced liver injury

Novel finding that links ALS/ataxia to cellular stress opens door to new treatment approaches

Family genetic background essential for understanding autism progression

Chemical signals influence guest-host protocell interactions

Daytime sleepiness found to be a potential risk factor for Alzheimer’s disease

Hsp90 protein appears to stimulate exosome release

Scientists discover key aspect in the development of multiple sclerosis

Exeter’s new system can probe microscopic environments inside cells

Study: Health and longevity improves with increased fasting time

New study aims to understand why skin grafts have high rate of rejection

Research team identifies new therapeutic target for castration-resistant prostate cancer

Ground-breaking therapeutic process can destroy bowel cancer cells

Research uncovers how the immune system detects DNA damage

Natural plant compound exploits newly identified Achilles' heel in uveal melanoma

Verastem doses first patient in Phase I/II clinical trial of duvelisib in combination with venetoclax

Research finds why foods high in unsaturated fats protect against cardiovascular disease

Researchers discover natural plant compound that shuts down uveal melanoma cell growth

New system accelerates discovery of chemical compounds that inhibit enzyme implicated in cancers

Discovering Prion-like Proteins in Eukaryotic Viruses

New nuclear medicine imaging method could help diagnose widespread tumors

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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