Protein C News and Research

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Study adds more evidence to underlying autoimmune mechanisms in type 1 diabetes

Immune reactions are usually a good thing - the body's way of eliminating harmful bacteria and other pathogens. But people also rely on molecular "brakes," or checkpoints, to keep immune systems from attacking their own cells and organs and causing so-called autoimmune disease.

29 Aug 2018

Soluble versions of immune cell protein could help treat Alzheimer's disease, study reveals

Researchers at the University of Florida have discovered that a modified version of an important immune cell protein could be used to treat Alzheimer's disease.

29 Aug 2018

Scientists discover potential treatment for Alzheimer’s disease

Scientists discovered a modified version of an immune cell receptor called a toll-like receptor that could be used as a treatment for Alzheimer’s disease.

29 Aug 2018

Researchers uncover why some cancers grow faster than others

University of Toronto researchers have uncovered why some cancers grow faster than others. The team led by Liliana Attisano, Professor in U of T's Donnelly Centre for Cellular and Biomolecular Research, has identified a protein called NUAK2, which is produced by cancer cells to boost their proliferation and whose presence in tumors is associated with poor disease prognosis.

29 Aug 2018

Lack of protein in father's diet can impact long-term health of his offspring

New research has shown that a lack of protein in a father's diet affects sperm quality which can have a direct impact on the long-term health of their offspring.

29 Aug 2018

New rapid imaging protocol quickly and cheaply detects heart ailments for people in Peru

A newly developed rapid imaging protocol quickly and cheaply diagnosed heart ailments in patients in Peru, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

29 Aug 2018

Research shows proteomics can be used to predict evolution of triple negative breast cancer

The rarest, but also the most aggressive and hard to treat form of breast cancer, is known as triple negative. For this type of cancer, researchers have so far been unable to identify markers that can classify patients by prognosis or probability of responding to different treatments.

29 Aug 2018

Protein aggregates may play protection role against toxic stresses

Protein aggregates have a bad reputation in conditions such as Alzheimer’s disease and Parkinson’s disease, but in bacteria, inheritance of aggregates by daughter cells may help protect against the same toxic stresses that triggered them in parental cells, according to a new study publishing 28 August in the open access journal PLOS Biology, by Sander Govers, Abram Aertsen, and colleagues at KU Leuven, Belgium.

29 Aug 2018

Researchers discover mechanism that steers growth of cancer cells in melanoma and liver cancer

Melanoma and liver cancer are becoming more widespread in Europe and the US. Whilst both diseases progress very differently, they are among the types of cancer which are most likely to be fatal in the Western world.

29 Aug 2018

Study suggests new strategies for using cell metabolism to treat cancer

Researchers at the University of Cincinnati College of Medicine have discovered that cell metabolism plays an important role in the ability of cells to start a survival program called autophagy, an unwanted side effect of some anti-cancer drugs that helps some tumor cells dodge treatment and eventually regrow into new tumors.

29 Aug 2018

Researchers find how NF2 gene mutations lead to out-of-control cellular proliferation

A team of Massachusetts General Hospital Cancer Center researchers has determined one way that mutations in a gene involved in a rare, hereditary cancer syndrome lead to out-of-control cellular proliferation.

29 Aug 2018

Scientists reveal how immune system strives to protect the lungs of infants with flu

The immune system appears to put a premium on maintaining lung function in infants infected with the influenza virus by mounting a rapid response to repair damaged cells, according to research led by St. Jude Children’s Research Hospital. The findings appear today in the scientific journal Immunity.

29 Aug 2018

New trial assesses criteria used to diagnose myocardial infarction

Results of the first randomized trial testing the criteria used to diagnose heart attack are presented today in a Hot Line Session at ESC Congress 2018 and published in The Lancet.

28 Aug 2018

Study could open new therapeutic avenues to attack herpesviruses

Human cytomegalovirus is a leading cause of birth defects and transplant failures. As it's evolved over time, this virus from the herpes family has found a way to bypass the body's defense mechanisms that usually guards against viral infections. Until now, scientists couldn't understand how it manages to do so.

28 Aug 2018

Obesity diminishes muscle building ability after resistance exercise, study reveals

Obesity is associated with a host of health problems, including heart disease, type 2 diabetes and high blood pressure. According to a new study reported in the Journal of Physiology, obesity also diminishes a person's ability to build muscle after engaging in resistance exercise.

28 Aug 2018

Scientists develop three-pronged model to predict ARDS in burn patients

For the first time, researchers have devised a model to predict burn patients who are most likely to develop life-threatening acute respiratory distress syndrome.

28 Aug 2018

Pediatric researchers discover gene mutation that causes lymphatic disorder

Pediatric researchers have identified a gene mutation that causes a serious lymphatic condition, and used that knowledge to restore normal lymphatic vessels in model animals. The laboratory findings may lead to a new therapy for patients with this type of abnormal lymphatic circulation.

28 Aug 2018