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Researchers find microbiome-controlled anti-inflammatory subsets of astrocytes

Astrocytes are the most abundant type of cells within the central nervous system (CNS), but they remain poorly characterized.

26 Jan 2021

Probiotics as adjuvant therapy for COVID-19 patients

In a recent review published in the Journal of Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Luigi Santacroce and Francesco Inchingolo et al. address the many factors such as dysbiosis (imbalance in the microbiota) that could influence the SARS-CoV-2 infection course.

25 Jan 2021

Newly designed Biomesh minimizes postsurgical complications of hernia repair

Hernias are one of the most common soft tissue injuries. Hernias form when intra-abdominal content, such as a loop of the intestine, squeezes through weak, defective or injured areas of the abdominal wall.

25 Jan 2021

Treating 'fetus as the patient' could reduce the incidence of pre-term labor and premature birth

The results of a study by researchers at the University of Texas Medical Branch may pave the way for a new medicine delivery system that could reduce the incidence of pre-term labor and premature birth by allowing physicians to treat the 'fetus as the patient'.

22 Jan 2021

NSAIDs dampen antibody and inflammatory responses to SARS-CoV-2 infection in mice

New research shows that non-steroidal anti-inflammatory drugs (NSAIDs) reduced both antibody and inflammatory responses to SARS-CoV-2 infection in mice. The study appears this week in the Journal of Virology, a publication of the American Society for Microbiology.

22 Jan 2021

Specific NSAIDs are metabolized by acyl-CoA synthetases leading to liver toxicity

Liver injury is a rare side effect of nonsteroidal anti-inflammatory drugs (NSAIDs), which are frequently used for daily pain control.

22 Jan 2021

Multimodal pain regimen minimizes opioid exposure, relieves acute pain in trauma patients

A multimodal pain regimen (MMPR) designed to minimize opioid exposure and relieve acute pain associated with traumatic injury kept patient self-reported pain scores low while also reducing the daily and total amount of opioid drugs given to trauma patients.

21 Jan 2021

Nicotine promotes breast cancer lung metastasis, finds study

Breast cancer is the second most common cancer among women in the United States, and cigarette smoking is associated with a higher incidence of breast cancer spread, or metastasis, lowering the survival rate by 33% at diagnosis.

21 Jan 2021

Systemic lupus erythematosus disproportionately affects ethnic female population

Just over 200,000 Americans suffer from systemic lupus erythematosus, or SLE, a condition in which the body's immune system mistakenly attacks its own healthy tissues, especially joints and skin, a new study shows.

21 Jan 2021

Arthritis drug is no better than standard care in improving severe COVID-19 outcomes, shows new trial

Adding the arthritis drug tocilizumab to standard care for patients in hospital with severe or critical covid-19 is no better than standard care alone in improving clinical outcomes at 15 days, finds a new trial published by The BMJ today.

20 Jan 2021

Early administration of ivermectin could help reduce viral transmission in COVID-19 patients

A small pilot study suggests that early administration of ivermectin can reduce viral loads and symptom duration in patients with mild COVID-19, which in turn could help reduce viral transmission.

19 Jan 2021

Combination therapy reduces recovery time in COVID-19 patients, clinical trial finds

A clinical trial involving COVID-19 patients hospitalized at UT Health San Antonio and University Health, among roughly 100 sites globally, found that a combination of the drugs baricitinib and remdesivir reduced time to recovery, according to results published Dec. 11 in the New England Journal of Medicine.

16 Jan 2021

New DNA test quickly identifies secondary infections in COVID-19 patients

Researchers have developed a DNA test to quickly identify secondary infections in COVID-19 patients, who have double the risk of developing pneumonia while on ventilation than non-COVID-19 patients.

15 Jan 2021

Metformin drug decreases mortality rate in COVID-19 patients with type 2 diabetes

Use of the diabetes drug metformin -- before a diagnosis of COVID-19 -- is associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes, according to a racially diverse study at the University of Alabama at Birmingham.

15 Jan 2021

Lab study reveals effective treatment for COVID-19

A new potential therapy for COVID-19 developed by researchers at Rush University Medical Center has shown success in preventing the disease's symptoms in mice.

14 Jan 2021

Study suggests SARS-CoV-2 could affect aquatic wildlife

Researchers have found that oxidative stress and neurotoxicity biomarkers increased in tadpoles exposed to synthetic SARS-CoV-2 spike protein peptides.

14 Jan 2021

Researchers develop a novel, patient-derived model of ulcerative colitis

As reported in Nature Communications, researchers from Cleveland Clinic's Lerner Research Institute have developed a novel, patient-derived model of ulcerative colitis, which will help advance studies into new treatments for the chronic inflammatory bowel disease.

11 Jan 2021

New probiotic coffee and tea drinks are packed with gut-friendly live probiotics

Good news for those who need a cuppa to start the day. Researchers from the National University of Singapore (NUS) have created new probiotic coffee and tea drinks that are packed with gut-friendly live probiotics.

10 Jan 2021

Patients taking immunosuppressive drugs did not have worse COVID-19 outcomes

People taking immunosuppressive drugs to prevent organ transplant rejection or to treat inflammatory or autoimmune diseases do not fare worse than others on average when they are hospitalized with COVID-19, according to a study from researchers at the Johns Hopkins Bloomberg School of Public Health.

7 Jan 2021

ACE2 receptor is responsible for the wide host range of SARS-CoV-2

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is thought to have a zoonotic origin, perhaps originating in a bat coronavirus with an unknown intermediate host. It is not only very infectious but has been found to infect a wide range of mammals, including dogs, cats, ferrets, hamsters, and minks, besides non-human primates. This range may be still higher, claims a recent preprint that appeared in January 2021 on the bioRxiv server.

6 Jan 2021

Anti Inflammatory News and Research

Researchers find microbiome-controlled anti-inflammatory subsets of astrocytes

Probiotics as adjuvant therapy for COVID-19 patients

Newly designed Biomesh minimizes postsurgical complications of hernia repair

Treating 'fetus as the patient' could reduce the incidence of pre-term labor and premature birth

NSAIDs dampen antibody and inflammatory responses to SARS-CoV-2 infection in mice

Specific NSAIDs are metabolized by acyl-CoA synthetases leading to liver toxicity

Multimodal pain regimen minimizes opioid exposure, relieves acute pain in trauma patients

Nicotine promotes breast cancer lung metastasis, finds study

Systemic lupus erythematosus disproportionately affects ethnic female population

Arthritis drug is no better than standard care in improving severe COVID-19 outcomes, shows new trial

Early administration of ivermectin could help reduce viral transmission in COVID-19 patients

Combination therapy reduces recovery time in COVID-19 patients, clinical trial finds

New DNA test quickly identifies secondary infections in COVID-19 patients

Metformin drug decreases mortality rate in COVID-19 patients with type 2 diabetes

Lab study reveals effective treatment for COVID-19

Study suggests SARS-CoV-2 could affect aquatic wildlife

Researchers develop a novel, patient-derived model of ulcerative colitis

New probiotic coffee and tea drinks are packed with gut-friendly live probiotics

Patients taking immunosuppressive drugs did not have worse COVID-19 outcomes

ACE2 receptor is responsible for the wide host range of SARS-CoV-2

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