Biochemistry News and Research

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Keto diet may cause skin problems

Researchers from Austria have found that ketogenic diets could affect psoriasis-like skin inflammation in mice. They noted that keto diets including medium-chain triglycerides (MCTs) such as coconut along with omega-3 fatty acids obtained from nuts and seeds and fish oil could be a recipe for psoriasis exacerbation. They speculated that this could be true for humans as well. The study titled, “The Influence of Ketogenic Diets on Psoriasiform-Like Skin Inflammation,” was published this week in the Journal of Investigative Dermatology.

17 Oct 2019

Chemists find new way to synthesize most common molecule arrangement in medicine

Organic chemists at The Ohio State University have figured out how to synthesize the most common molecule arrangement in medicine, a scientific discovery that could change the way a number of drugs - including one most commonly used to treat ovarian cancer - are produced.

17 Oct 2019

Researchers obtain 3D structural snapshots of key regulator of cell biology

Some of the greatest insights into cancer and how to treat it come when basic scientists and cancer biologists and clinicians collaborate.

17 Oct 2019

Wistar receives major NIH grant to advance research on new melanoma targeted therapies

The Wistar Institute and collaborating institutions have received a major grant from the National Institutes of Health to further research on new melanoma targeted therapies integrating the role of the tumor microenvironment in influencing response to therapy and development of resistance.

17 Oct 2019

Researchers identify compounds that could help study the toxicological properties of fire ant venom

Native to South America, imported fire ants have now spread to parts of North America and elsewhere around the world. These invasive pests have painful stings that, in some cases, can cause serious medical problems, such as hypersensitivity reactions, infections and even kidney failure.

17 Oct 2019

Study underlines the importance of composition of fatty acids in diet

Not all fats are equal in how they affect our skin, according to a new study in the Journal of Investigative Dermatology, published by Elsevier.

17 Oct 2019

ALS patients with commonly inherited genetic variation may experience more severe symptoms

A discovery made several years ago in a lab researching asthma at Wake Forest School of Medicine may now have implications for the treatment of amyotrophic lateral sclerosis (ALS), a disease with no known cure and only two FDA-approved drugs to treat its progression and severity.

16 Oct 2019

Study suggests new model of treatment for heart attack or stroke victims

Each year, heart attacks kill almost 10 million people in the world, and more than 6 million die from stroke. A heart attack is caused by a clot that blocks the artery blood flow. Unirrigated tissues are deprived from the oxygen that is carried by the blood. Under these conditions, the affected tissues undergo a rapid necrosis.

15 Oct 2019

New microfluidic test can detect Lyme disease within 15 minutes

Some 300,000 people in the U.S. are diagnosed with Lyme disease every year. Caused by Borrelia burgdorferi and transmitted by the bite of infected Ixodes ticks, the disease if left untreated can cause serious neurologic, cardiac, and/or rheumatologic complications.

11 Oct 2019

€7.6 million ERC Synergy grant to support research on molecular mechanisms of viral infection

The interdisciplinary team wants to investigate the molecular mechanisms of viral infection, which will contribute to fundamental knowledge about cellular regulation and new concepts for broad-spectrum anti-viral therapy. The funding amounts to 7.6 million euros.

11 Oct 2019

Genetic oscillator captures changes in gut microbiome growth patterns

For all the attention the human microbiome has been getting over the last few years, one aspect of such research rarely makes headlines: the difficulty of observing how it changes over time in response to various stimuli.

11 Oct 2019

New study finds genetic link for some forms of SIDS

A genetic link has now been found for some instances of Sudden Infant Death Syndrome, or SIDS. The new UW Medicine research study is the first to make an explainable link tracking the mechanism between a genetic anomaly and some forms of the devastating syndrome, which claims the lives of more than 3,000 infants a year.

11 Oct 2019

Scientists find new evidence on latent HIV reservoir

Antiretroviral therapy (ART) can suppress HIV to the point where the virus is nearly undetectable, and people on medication can live many years.

10 Oct 2019

Initial use of ART alters host environment to allow formation of long-lived HIV reservoir

Antiretroviral therapy (ART) can suppress HIV to the point where the virus is nearly undetectable, and people on medication can live many years. But therapy cannot completely eradicate the virus; it persists in reservoirs inside immune cells, a phenomenon called "latency."

9 Oct 2019

New antibiotic discovered in Mexican tropical forest

Scientists from Rutgers University and around the world have discovered an antibiotic produced by a soil bacterium from a Mexican tropical forest that may help lead to a "plant probiotic," more robust plants and other antibiotics.

8 Oct 2019

Using blood and plasma for earlier detection of Alzheimer's disease

The promise of earlier detection of diseases such as Alzheimer's is welcome news to the millions of families in the United States already affected by the various types of dementia. Emerging techniques such as spinal taps have shown success, but they are not effective for everyone.

8 Oct 2019

University of Notre Dame receives funding to help launch diabetic ulcer drug over 'Valley of Death'

Thousands of new chemical structures are tested in hopes of discovering a single drug meant to treat a single disease. Of the 5,000 to 10,000 that are prepared, only about 250 of those make it to the pre-clinical stage, and potentially as few as five make it to clinical trials in humans.

8 Oct 2019

Eye disease in infants detected using smartphone app

Examining eyes in babies is difficult to say the least. Researchers at the Baylor University in Waco, Texas, have come up with a smart phone app that could help ophthalmologists detect eye diseases in infants. The results of the testing of the app were published in the latest issue of the journal Science Advances.

8 Oct 2019

New link between two important products of nitric oxide discovered

Ever since three US-based researchers working independently unveiled the role of nitric oxide in mediating blood vessel dilation, endothelial cell contraction and smooth muscle relaxation, their discoveries have served as a basis for novel treatments for high blood pressure and erectile dysfunction, among other conditions.

4 Oct 2019

GW researchers show connection between bacteria in the microbiome and colon cancer

A mutant protein found in humans with colon cancer blocks a pathway that regulates proliferation and expansion of cells, increasing amounts of bacterial species associated with the development of colon cancer.

4 Oct 2019

Biochemistry News and Research

Keto diet may cause skin problems

Chemists find new way to synthesize most common molecule arrangement in medicine

Researchers obtain 3D structural snapshots of key regulator of cell biology

Wistar receives major NIH grant to advance research on new melanoma targeted therapies

Researchers identify compounds that could help study the toxicological properties of fire ant venom

Study underlines the importance of composition of fatty acids in diet

ALS patients with commonly inherited genetic variation may experience more severe symptoms

Study suggests new model of treatment for heart attack or stroke victims

New microfluidic test can detect Lyme disease within 15 minutes

€7.6 million ERC Synergy grant to support research on molecular mechanisms of viral infection

Genetic oscillator captures changes in gut microbiome growth patterns

New study finds genetic link for some forms of SIDS

Scientists find new evidence on latent HIV reservoir

Initial use of ART alters host environment to allow formation of long-lived HIV reservoir

New antibiotic discovered in Mexican tropical forest

Using blood and plasma for earlier detection of Alzheimer's disease

University of Notre Dame receives funding to help launch diabetic ulcer drug over 'Valley of Death'

Eye disease in infants detected using smartphone app

New link between two important products of nitric oxide discovered

GW researchers show connection between bacteria in the microbiome and colon cancer

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